PIPA5105226
Phospho-MNK1 (Thr250, Thr255) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5105226-Each-of-1 | In Stock | ₹ 45,218.46 |
PIPA5105226 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,218.46
GST (18%): ₹ 8,139.323
Total Price: ₹ 53,357.783
Antigen
Phospho-MNK1 (Thr250, Thr255)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
MKNK1
Gene Alias
2410048M24Rik; MAP kinase interacting serine/threonine kinase 1; MAP kinase signal-integrating kinase 1; MAP kinase-interacting serine/threonine kinase 1; MAP kinase-interacting serine/threonine-protein kinase 1; MAPK signal-integrating kinase 1; MKNK1; Mnk1; OTTHUMP00000009675; OTTHUMP00000009676
Host Species
Rabbit
Purification Method
sequential chromatography
Regulatory Status
RUO
Gene ID (Entrez)
17346, 8569
Content And Storage
-20°C
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
O08605, Q9BUB5
Gene Symbols
MKNK1
Immunogen
A synthesized peptide derived from human MKNK1(Accession Q9BUB5), corresponding to amino acid residues around phosphorylated Thr250.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of Mnk1 only when phosphorylated at Thr250/255
- The Map kinase-interacting kinases (MKNK1 and MKNK2) are activated by Map kinases, regulate protein synthesis by phosphroylation eIF4E on Ser209, and may contribute to tumorigenesis
- Overexpression of Mnk2 results in increased phosphorylation of endogenous eIF-4E, showing that it can act as an eIF-4E kinase in vivo
- Mnk2 may play a role in the response to environmental stress and cytokines
- Expression of active mutants of MNK1 and MNK2 in 293 cells diminishes cap-dependent translation relative to cap-independent translation in a transient reporter assay
- Human Mnk2 is homologous to murine Mnk2 (approximately 94% identical) and human Mnk1 (71% identical)
- In vitro phosphorylation studies show that Mnk2 is a significantly better substrate than Mnk1 for extracellular signal-regulated kinase 2 (Erk2), p38MAPKalpha, and p38MAPKbeta.
Compare Similar Items
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Antigen: Phospho-MNK1 (Thr250, Thr255)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MKNK1
Gene Alias: 2410048M24Rik; MAP kinase interacting serine/threonine kinase 1; MAP kinase signal-integrating kinase 1; MAP kinase-interacting serine/threonine kinase 1; MAP kinase-interacting serine/threonine-protein kinase 1; MAPK signal-integrating kinase 1; MKNK1; Mnk1; OTTHUMP00000009675; OTTHUMP00000009676
Host Species: Rabbit
Purification Method: sequential chromatography
Regulatory Status: RUO
Gene ID (Entrez): 17346, 8569
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: O08605, Q9BUB5
Gene Symbols: MKNK1
Immunogen: A synthesized peptide derived from human MKNK1(Accession Q9BUB5), corresponding to amino acid residues around phosphorylated Thr250.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-MNK1 (Thr250, Thr255)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MKNK1
Gene Alias:
2410048M24Rik; MAP kinase interacting serine/threonine kinase 1; MAP kinase signal-integrating kinase 1; MAP kinase-interacting serine/threonine kinase 1; MAP kinase-interacting serine/threonine-protein kinase 1; MAPK signal-integrating kinase 1; MKNK1; Mnk1; OTTHUMP00000009675; OTTHUMP00000009676
Host Species:
Rabbit
Purification Method:
sequential chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
17346, 8569
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
O08605, Q9BUB5
Gene Symbols:
MKNK1
Immunogen:
A synthesized peptide derived from human MKNK1(Accession Q9BUB5), corresponding to amino acid residues around phosphorylated Thr250.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-CARD11 (Ser652)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CARD11
Gene Alias: 0610008L17Rik; 2410011D02Rik; bcl10-interacting maguk protein 3; BENTA; BIMP3; Card11; CARD-containing MAGUK protein 1; Carma 1; CARMA1; caspase recruitment domain family member 11; caspase recruitment domain family, member 11; caspase recruitment domain-containing protein 11; IMD11; LOC100363332; MGC133069; PPBL
Host Species: Rabbit
Purification Method: sequential chromatography
Regulatory Status: RUO
Gene ID (Entrez): 100363332, 108723, 84433
Content And Storage: -20°C
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: Q8CIS0, Q9BXL7
Gene Symbols: CARD11
Immunogen: A synthesized peptide derived from human CARD11(Accession Q9BXL7), corresponding to amino acid residues around phosphorylated Ser652.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-CARD11 (Ser652)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CARD11
Gene Alias:
0610008L17Rik; 2410011D02Rik; bcl10-interacting maguk protein 3; BENTA; BIMP3; Card11; CARD-containing MAGUK protein 1; Carma 1; CARMA1; caspase recruitment domain family member 11; caspase recruitment domain family, member 11; caspase recruitment domain-containing protein 11; IMD11; LOC100363332; MGC133069; PPBL
Host Species:
Rabbit
Purification Method:
sequential chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
100363332, 108723, 84433
Content And Storage:
-20°C
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
Q8CIS0, Q9BXL7
Gene Symbols:
CARD11
Immunogen:
A synthesized peptide derived from human CARD11(Accession Q9BXL7), corresponding to amino acid residues around phosphorylated Ser652.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-PINK1 (Thr313)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PINK1
Gene Alias: 1190006F07Rik; AU042772; AW557854; BRPK; FLJ27236; mFLJ00387; PARK6; PINK 1; Pink1; PINK-1; protein kinase BRPK; PTEN induced putative kinase 1; PTEN-induced putative kinase protein 1; Serine/threonine-protein kinase PINK1, mitochondrial
Host Species: Rabbit
Purification Method: sequential chromatography
Regulatory Status: RUO
Gene ID (Entrez): 65018, 68943
Content And Storage: -20°C
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: Q99MQ3, Q9BXM7
Gene Symbols: PINK1
Immunogen: A synthesized peptide derived from human PINK1(Accession Q9BXM7), corresponding to amino acid residues around phosphorylated Thr313.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-PINK1 (Thr313)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PINK1
Gene Alias:
1190006F07Rik; AU042772; AW557854; BRPK; FLJ27236; mFLJ00387; PARK6; PINK 1; Pink1; PINK-1; protein kinase BRPK; PTEN induced putative kinase 1; PTEN-induced putative kinase protein 1; Serine/threonine-protein kinase PINK1, mitochondrial
Host Species:
Rabbit
Purification Method:
sequential chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
65018, 68943
Content And Storage:
-20°C
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
Q99MQ3, Q9BXM7
Gene Symbols:
PINK1
Immunogen:
A synthesized peptide derived from human PINK1(Accession Q9BXM7), corresponding to amino acid residues around phosphorylated Thr313.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-CDCP1 (Tyr707)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Cdcp1
Gene Alias: 9030022E12Rik; AA409659; CD318; CDCP1; CUB domain containing protein 1; CUB domain-containing protein 1; E030027H19Rik; gp140; Membrane glycoprotein gp140; RGD1305578; SIMA135; Subtractive immunization M plus HEp3-associated 135 kDa protein; transmembrane and associated with src kinases; TRASK; UNQ2486/PRO5773
Host Species: Rabbit
Purification Method: sequential chromatography
Regulatory Status: RUO
Gene ID (Entrez): 109332, 301082, 64866
Content And Storage: -20°C
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: Q5U462, Q9H5V8
Gene Symbols: Cdcp1
Immunogen: A synthesized peptide derived from human CDCP1(Accession Q9H5V8), corresponding to amino acid residues around phosphorylated Tyr707.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-CDCP1 (Tyr707)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Cdcp1
Gene Alias:
9030022E12Rik; AA409659; CD318; CDCP1; CUB domain containing protein 1; CUB domain-containing protein 1; E030027H19Rik; gp140; Membrane glycoprotein gp140; RGD1305578; SIMA135; Subtractive immunization M plus HEp3-associated 135 kDa protein; transmembrane and associated with src kinases; TRASK; UNQ2486/PRO5773
Host Species:
Rabbit
Purification Method:
sequential chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
109332, 301082, 64866
Content And Storage:
-20°C
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
Q5U462, Q9H5V8
Gene Symbols:
Cdcp1
Immunogen:
A synthesized peptide derived from human CDCP1(Accession Q9H5V8), corresponding to amino acid residues around phosphorylated Tyr707.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG