PIPA5105356

Phospho-PINK1 (Ser228) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5105356-Each-of-1 In Stock ₹ 49,753.14

PIPA5105356 - Each of 1

₹ 49,753.14

In Stock

Quantity

1

Base Price: ₹ 49,753.14

GST (18%): ₹ 8,955.565

Total Price: ₹ 58,708.705

Antigen

Phospho-PINK1 (Ser228)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

PINK1

Gene Alias

1190006F07Rik; AU042772; AW557854; BRPK; FLJ27236; mFLJ00387; PARK6; PINK 1; Pink1; PINK-1; protein kinase BRPK; PTEN induced putative kinase 1; PTEN-induced putative kinase protein 1; Serine/threonine-protein kinase PINK1, mitochondrial

Host Species

Rabbit

Purification Method

sequential chromatography

Regulatory Status

RUO

Gene ID (Entrez)

298575, 65018, 68943

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

B5DFG1, Q99MQ3, Q9BXM7

Gene Symbols

PINK1

Immunogen

A synthesized peptide derived from human PINK1(Accession Q9BXM7), corresponding to amino acid residues around phosphorylated Ser228.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of PINK1 only when phosphorylated at Ser228
  • PINK1 (PTEN-induced putative kinase 1) protects from mitochondrial dysfunction in cells by conferring different autophosphorylation activity to mitochondrial genes
  • The kinase domain of PINK1 appears to be critical in its protective effects
  • Mitochondrial proteins are critical for the regulation of cellular energy and adaptation to stress
  • Particularly in brain cells, mitochondrial demand is extraordinarily high, in order to accommodate aerobic and anaerobic support of high energy processes
  • When mitochondrial structure and/or function is disrupted in the brain, neurodegenerative diseases like Parkinson's disease are triggered.

Compare Similar Items

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Img

Thermo Scientific

PIPA5105356

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Antigen:
Phospho-PINK1 (Ser228)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PINK1

Gene Alias:
1190006F07Rik; AU042772; AW557854; BRPK; FLJ27236; mFLJ00387; PARK6; PINK 1; Pink1; PINK-1; protein kinase BRPK; PTEN induced putative kinase 1; PTEN-induced putative kinase protein 1; Serine/threonine-protein kinase PINK1, mitochondrial

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
298575, 65018, 68943

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
B5DFG1, Q99MQ3, Q9BXM7

Gene Symbols:
PINK1

Immunogen:
A synthesized peptide derived from human PINK1(Accession Q9BXM7), corresponding to amino acid residues around phosphorylated Ser228.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5105361

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Antigen:
Phospho-Annexin A4 (Tyr255)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ANXA4

Gene Alias:
35-beta calcimedin; 36 kDa zymogen granule membrane-associated protein; AI265406; AIV; annexin 4; annexin A4; Annexin IV; annexin IV (placental anticoagulant protein II); annexin-4; ANX IV; ANX4; ANXA 4; Anxa4; ANXIV; AW106930; Carbohydrate-binding protein p33/p41; chromobindin-4; endonexin; endonexin I; epididymis secretory protein Li 274; HEL-S-274; Lipocortin IV; P32.5; p33/41 (annexin IV); PAP-II; PIG28; Placental anticoagulant protein II; PP4-X; proliferation-inducing gene 28; proliferation-inducing protein 28; Protein II; unnamed protein product; Xanx-4; ZAP 36/annexin IV; ZAP36; zymogen granule membrane associated protein

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11746, 307

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P09525, P97429

Gene Symbols:
ANXA4

Immunogen:
A synthesized peptide derived from human ANXA4(Accession P09525), corresponding to amino acid residues around phosphorylated Tyr255.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

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PIPA5105362

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Antigen:
Phospho-ATG3 (Tyr18)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ATG3

Gene Alias:
2610016C12Rik; APG3; Apg3l; APG3-like; Apg3p; atg3; ATG3 autophagy related 3 homolog; atg3.S; Atg3l; autophagy related 3; autophagy related 3 S homeolog; autophagy-related 3; autophagy-related protein 3; DKFZp564M1178; EGK_11288; FLJ22125; hApg3; MGC15201; PC3-96; Pig1; PIG-1; preconditioning-inducible gene 1 protein; Protein PC3-96; Ubiquitin-like-conjugating enzyme ATG3; XELAEV_18014721mg

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
171415, 64422, 67841

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q6AZ50, Q9CPX6, Q9NT62

Gene Symbols:
ATG3

Immunogen:
A synthesized peptide derived from human ATG3(Accession Q9NT62), corresponding to amino acid residues around phosphorylated Tyr18.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5105364

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Antigen:
Phospho-BACH1 (Ser445)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
BACH1

Gene Alias:
6230421P05Rik; AI323795; BACH1; BACH-1; basic region leucine zipper transcriptional regulator BACH1; BTB and CNC homolog 1; BTB and CNC homology 1; BTB and CNC homology 1 transcription factor; BTB and CNC homology 1, basic leucine zipper transcription factor 1; BTB domain and CNC homolog 1; BTBD24; HA2303; Transcription regulator protein BACH1

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12013, 304127, 571

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O14867, P97302

Gene Symbols:
BACH1

Immunogen:
A synthesized peptide derived from human BACH1(Accession O14867), corresponding to amino acid residues around phosphorylated Ser445.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG