PIPA5105075

Phospho-SLP76 (Tyr173) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5105075-Each-of-1 In Stock ₹ 44,705.10

PIPA5105075 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

Phospho-SLP76 (Tyr173)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

LCP2

Gene Alias

76 kDa tyrosine phosphoprotein; AI323664; BB161688; Lcp2; Lymphocyte cytosolic protein 2; lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa); lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76kD); SH2 domain-containing leukocyte protein of 76 kDa; SH2 domain-containing leukocyte protein of 76kD; SLP76; SLP-76; SLP-76 tyrosine phosphoprotein; twm

Host Species

Rabbit

Purification Method

sequential chromatography

Regulatory Status

RUO

Gene ID (Entrez)

155918, 16822, 3937

Content And Storage

-20°C

Form

Liquid

Applications

Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

Q13094, Q60787

Gene Symbols

LCP2

Immunogen

A synthesized peptide derived from human LCP2(Accession Q13094), corresponding to amino acid residues around phosphorylated Tyr173.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of SLP76 only when phosphorylated at Tyr173
  • SLP-76 was originally identified as a substrate of the ZAP-70 protein tyrosine kinase following T cell receptor (TCR) ligation in the leukemic T cell line Jurkat
  • The SLP-76 locus has been localized to human chromosome 5q33 and the gene structure has been partially characterized in mice
  • The human and murine cDNAs both encode 533 amino acid proteins that are 72% identical and comprised of three modular domains
  • The NH2-terminus contains an acidic region that includes a PEST domain and several tyrosine residues which are phosphorylated following TCR ligation
  • SLP-76 also contains a central proline-rich domain and a COOH-terminal SH2 domain
  • A number of additional proteins have been identified that associate with SLP-76 both constitutively and inducibly following receptor ligation, supporting the notion that SLP-76 functions as an adaptor or scaffold protein
  • Studies using SLP-76 deficient T cell lines or mice have provided strong evidence that SLP-76 plays a positive role in promoting T cell development and activation as well as mast cell and platelet function.

Compare Similar Items

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Img

Thermo Scientific

PIPA5105075

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Antigen:
Phospho-SLP76 (Tyr173)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
LCP2

Gene Alias:
76 kDa tyrosine phosphoprotein; AI323664; BB161688; Lcp2; Lymphocyte cytosolic protein 2; lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa); lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76kD); SH2 domain-containing leukocyte protein of 76 kDa; SH2 domain-containing leukocyte protein of 76kD; SLP76; SLP-76; SLP-76 tyrosine phosphoprotein; twm

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
155918, 16822, 3937

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q13094, Q60787

Gene Symbols:
LCP2

Immunogen:
A synthesized peptide derived from human LCP2(Accession Q13094), corresponding to amino acid residues around phosphorylated Tyr173.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5105078

--


Antigen:
Phospho-ITCH / AIP4 (Tyr420)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ITCH

Gene Alias:
6720481N21Rik; 8030492O04Rik; A130065M08; ADMFD; AIF4; AIP4; atrophin-1 interacting protein 4; Atrophin-1-interacting protein 4; C230047C07Rik; dJ468O1.1; E3 ubiquitin-protein ligase Itchy; E3 ubiquitin-protein ligase Itchy homolog; HECT-type E3 ubiquitin transferase Itchy homolog; ITCH; itch E3 ubiquitin ligase; itchy E3 ubiquitin protein ligase; itchy E3 ubiquitin protein ligase homolog; itchy, E3 ubiquitin protein ligase; NAPP1; NFE2-associated polypeptide 1

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16396, 83737

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q8C863, Q96J02

Gene Symbols:
ITCH

Immunogen:
A synthesized peptide derived from human ITCH(Accession Q96J02), corresponding to amino acid residues around phosphorylated Tyr420.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5105081

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Antigen:
Phospho-SAR1A (Thr139)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SAR1A

Gene Alias:
1600019H17Rik; COPII-associated small GTPase; GTP-binding protein SAR1a; masra2; SAR1; SAR1 gene homolog A; SAR1 gene homolog A (S. cerevisiae); SAR1 homolog A; SAR1A; SAR1a gene homolog 1; Sara; Sara1; secretion associated Ras related GTPase 1A; secretion associated, Ras related GTPase 1A

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20224, 361842, 56681

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P36536, Q9NR31

Gene Symbols:
SAR1A

Immunogen:
A synthesized peptide derived from human SAR1A(Accession Q9NR31), corresponding to amino acid residues around phosphorylated Thr139.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5105082

--


Antigen:
Phospho-PPAR delta (Thr256)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Ppard

Gene Alias:
FAAR; MGC3931; Nr1c2; NUC1; NUC-1; NUCI; NUCII; nuclear hormone receptor; nuclear hormone receptor 1; Nuclear receptor subfamily 1 group C member 2; OTTHUMP00000016256; OTTHUMP00000016257; peroxisome proliferative activated receptor delta; peroxisome proliferator; peroxisome proliferator activated receptor; peroxisome proliferator activated receptor beta; peroxisome proliferator activated receptor delta; peroxisome proliferator activator receptor beta; peroxisome proliferator activator receptor delta; peroxisome proliferator activator receptor, delta; peroxisome proliferator-activated nuclear receptor beta/delta variant 2; Peroxisome proliferator-activated receptor beta; Peroxisome proliferator-activated receptor delta; PPAR[b]; PPARB; Pparb/d; PPARbeta; PPAR-beta; Ppard; PPARdelta; PPAR-delta; PPARdelta/beta

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
19015, 25682, 397297, 5467

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P35396, Q03181

Gene Symbols:
Ppard

Immunogen:
A synthesized peptide derived from human PPARD(Accession Q03181), corresponding to amino acid residues around phosphorylated Thr256.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Porcine, Rat

Product Type:
Antibody

Isotype:
IgG