PIPA5105200

Phospho-SLP76 (Ser376) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5105200-Each-of-1 In Stock ₹ 43,592.82

PIPA5105200 - Each of 1

₹ 43,592.82

In Stock

Quantity

1

Base Price: ₹ 43,592.82

GST (18%): ₹ 7,846.708

Total Price: ₹ 51,439.528

Antigen

Phospho-SLP76 (Ser376)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

LCP2

Gene Alias

76 kDa tyrosine phosphoprotein; AI323664; BB161688; Lcp2; Lymphocyte cytosolic protein 2; lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa); lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76kD); SH2 domain-containing leukocyte protein of 76 kDa; SH2 domain-containing leukocyte protein of 76kD; SLP76; SLP-76; SLP-76 tyrosine phosphoprotein; twm

Host Species

Rabbit

Purification Method

sequential chromatography

Regulatory Status

RUO

Gene ID (Entrez)

16822, 3937

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

Q13094, Q60787

Gene Symbols

LCP2

Immunogen

A synthesized peptide derived from human LCP2(Accession Q13094), corresponding to amino acid residues around phosphorylated Ser376.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of SLP76 only when phosphorylated at Ser376
  • SLP-76 was originally identified as a substrate of the ZAP-70 protein tyrosine kinase following T cell receptor (TCR) ligation in the leukemic T cell line Jurkat
  • The SLP-76 locus has been localized to human chromosome 5q33 and the gene structure has been partially characterized in mice
  • The human and murine cDNAs both encode 533 amino acid proteins that are 72% identical and comprised of three modular domains
  • The NH2-terminus contains an acidic region that includes a PEST domain and several tyrosine residues which are phosphorylated following TCR ligation
  • SLP-76 also contains a central proline-rich domain and a COOH-terminal SH2 domain
  • A number of additional proteins have been identified that associate with SLP-76 both constitutively and inducibly following receptor ligation, supporting the notion that SLP-76 functions as an adaptor or scaffold protein
  • Studies using SLP-76 deficient T cell lines or mice have provided strong evidence that SLP-76 plays a positive role in promoting T cell development and activation as well as mast cell and platelet function.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA5105200

--


Antigen:
Phospho-SLP76 (Ser376)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
LCP2

Gene Alias:
76 kDa tyrosine phosphoprotein; AI323664; BB161688; Lcp2; Lymphocyte cytosolic protein 2; lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa); lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76kD); SH2 domain-containing leukocyte protein of 76 kDa; SH2 domain-containing leukocyte protein of 76kD; SLP76; SLP-76; SLP-76 tyrosine phosphoprotein; twm

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16822, 3937

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q13094, Q60787

Gene Symbols:
LCP2

Immunogen:
A synthesized peptide derived from human LCP2(Accession Q13094), corresponding to amino acid residues around phosphorylated Ser376.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5105201

--


Antigen:
Phospho-SLP76 (Tyr145)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
LCP2

Gene Alias:
76 kDa tyrosine phosphoprotein; AI323664; BB161688; Lcp2; Lymphocyte cytosolic protein 2; lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa); lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76kD); SH2 domain-containing leukocyte protein of 76 kDa; SH2 domain-containing leukocyte protein of 76kD; SLP76; SLP-76; SLP-76 tyrosine phosphoprotein; twm

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
155918, 16822, 3937

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q13094, Q60787

Gene Symbols:
LCP2

Immunogen:
A synthesized peptide derived from human LCP2(Accession Q13094), corresponding to amino acid residues around phosphorylated Tyr145.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5105204

--


Antigen:
Phospho-PLD1 (Thr147)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PLD1

Gene Alias:
AA536939; C85393; choline phosphatase 1; hPLD1; mPLD1; phophatidylcholine-specific; Phoshpolipase D gene 1 probably with two splicing variants A and B; phosphatidylcholine-hydrolyzing phospholipase D1; phospholipase D gene 1, probably with two splicing variants A and B; phospholipase D1; phospholipase D1, phosphatidylcholine-specific; PLD 1; Pld1; Pld1a; Pld1b; Plda; Pldb; rPLD1

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18805, 25096, 5337

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P70496, Q13393, Q9Z280

Gene Symbols:
PLD1

Immunogen:
A synthesized peptide derived from human PLD1(Accession Q13393), corresponding to amino acid residues around phosphorylated Thr147.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5105206

--


Antigen:
Phospho-ATR (Thr1989)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ATR

Gene Alias:
2310008J16Rik; 2810405N18Rik; ataxia telangiectasia and Rad3 related; ataxia telangiectasia and Rad3-related protein; ATR; ATR serine/threonine kinase; EC 2.7.11.1; FCTCS; FRAP-related protein 1; FRAP-related protein-1; FRP1; I79_000761; kinase ATR; MEC1; MEC1, mitosis entry checkpoint 1, homolog; protein kinase ATR; SCKL; SCKL1; Serine/threonine-protein kinase ATR; TEM8

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
245000, 545

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q13535, Q9JKK8

Gene Symbols:
ATR

Immunogen:
A synthesized peptide derived from human ATR(Accession Q13535), corresponding to amino acid residues around phosphorylated Thr1989.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG