PIPA5105165

Phospho-IRS1 (Ser323) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5105165-Each-of-1 In Stock ₹ 44,705.10

PIPA5105165 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

Phospho-IRS1 (Ser323)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

IRS1

Gene Alias

G972R; HIRS-1; Insulin receptor substrate 1; IRS1; IRS-1; IRS1IRM; pp185

Host Species

Rabbit

Purification Method

sequential chromatography

Regulatory Status

RUO

Gene ID (Entrez)

16367, 25467, 3667

Content And Storage

-20°C

Form

Liquid

Applications

Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

P35568, P35569, P35570

Gene Symbols

IRS1

Immunogen

A synthesized peptide derived from human IRS1(Accession P35568), corresponding to amino acid residues around phosphorylated Ser323.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Related Products

Img

Thermo Scientific

PIPA5105164

--

Img

Thermo Scientific

PIPA5104877

--

Img

Thermo Scientific

PIPA5110129

--

Img

Thermo Scientific

PIPA5104831

--

Img

Thermo Scientific

PIPA5105092

--

Img

Thermo Scientific

PIPA5105121

--

Img

Thermo Scientific

PIPA5105150

--

Img

Thermo Scientific

PIPA5105233

--

Description

  • Antibody detects endogenous levels of IRS1 only when phosphorylated at Ser323, which site historically referenced as Ser318
  • IRS-1, a major substrate of the insulin receptor, is phosphorylated in response to stimulation of cells by insulin, insulin-like growth factor 1 (IGF-1) and interleukin 4 (IL-4)
  • IRS-1 is phosphorylated on serine, threonine and tyrosine residues in a variety of tissues
  • An insulin-sensitive serine/threonine kinase casein kinase II mediates a portion of the insulin-stimulated serine/threonine phosphorylation of overexpressed IRS-1 in vivo
  • Thr 502 is identified as the major casein kinase II-catalyzed phosphorylation site in rat IRS-1, and Ser 99 is an additional phosphorylation site catalyzed by casein kinase II
  • Thus, casein kinase II-catalyzed phosphorylation of IRS-1 may be a component of the intracellular insulin signaling cascade
  • IRS-1 contains three putative binding sites for 14-3-3 (Ser 270, Ser 374 and Ser 641) and the motif around Ser 270 is located in the phosphortyrosine binding domain of IRS-1, which is responsible for the interaction with the insulin receptor.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA5105165

--


Antigen:
Phospho-IRS1 (Ser323)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IRS1

Gene Alias:
G972R; HIRS-1; Insulin receptor substrate 1; IRS1; IRS-1; IRS1IRM; pp185

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16367, 25467, 3667

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P35568, P35569, P35570

Gene Symbols:
IRS1

Immunogen:
A synthesized peptide derived from human IRS1(Accession P35568), corresponding to amino acid residues around phosphorylated Ser323.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5105166

--


Antigen:
Phospho-MYH9 (Ser1943)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MYH9

Gene Alias:
BDPLT6; Cellular myosin heavy chain, type A; DFNA17; epsts; fi22c04; fj85e11; flectin; Fltn; FTNS; KLG/PTK7; LOC100911597; LOW QUALITY PROTEIN: myosin-9; MGC104539; MHA; Myh9; myh9.L; myh9a; myh9l2; Myhn1; Myhn-1; myosin; Myosin Heavy Chain 2A; myosin heavy chain 9; myosin heavy chain IX; myosin heavy chain, non-muscle IIa; myosin IIA; myosin, heavy chain 9, non-muscle; myosin, heavy chain 9, non-muscle L homeolog; myosin, heavy chain 9, non-muscle, like-2; myosin, heavy chain 9a, non-muscle; myosin, heavy polypeptide 9, non-muscle; myosin, heavy polypeptide 9a, non-muscle; myosin-2a; myosin9; Myosin-9; myosin-9; myosin-9a; myosin-9-like; NMHC II-A; NMHC-II A; NMHCIIA; NMHC-II-A; NMMHC IIA; NMMHC II-a; nmmhca; NMMHC-A; NMMHC-IIA; non-muscle myosin heavy chain 9; non-muscle myosin heavy chain A; non-muscle myosin heavy chain II A; non-muscle myosin heavy chain IIa; nonmuscle myosin heavy chain II-A; non-muscle myosin heavy polypeptide 9; nonmuscle myosin II heavy chain A; TU72.6; Unknown (protein for IMAGE:7151033); Unknown (protein for IMAGE:7177375); Unknown (protein for IMAGE:7268224); wu:fi22c04; wu:fi22c04 protein; wu:fj85e11; XELAEV_18023533mg; zgc:162029; zgc:66164; zNMHC-IIA

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100911597, 17886, 4627

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P35579, Q62812, Q8VDD5

Gene Symbols:
MYH9

Immunogen:
A synthesized peptide derived from human MYH9(Accession P35579), corresponding to amino acid residues around phosphorylated Ser1943.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5105168

--


Antigen:
Phospho-FLT3 (Tyr842)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
FLT3

Gene Alias:
B230315G04; CD135; CD135 antigen; fetal liver kinase 2; Fetal liver kinase-2; FL cytokine receptor; FLK2; Flk-2; FLT3; Flt-3; fms related tyrosine kinase 3; FMS-like tyrosine kinase 3; fms-related tyrosine kinase 3; growth factor receptor tyrosine kinase type III; Ly72; OTTHUMP00000214829; Receptor-type tyrosine-protein kinase FLT3; RP11-153M24.3; stem cell tyrosine kinase 1; STK1; STK-1; tyrosine-protein kinase FLT3; tyrosine-protein kinase receptor flk-2; wmfl

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
140635, 14255, 2322

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P36888, Q00342

Gene Symbols:
FLT3

Immunogen:
A synthesized peptide derived from human FLT3(Accession P36888), corresponding to amino acid residues around phosphorylated Tyr842.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5105169

--


Antigen:
Phospho-SREBP1 (Ser396)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SREBF1

Gene Alias:
ADD1; ADD-1; Adipocyte determination- and differentiation-dependent factor 1; bHLHd1; Class D basic helix-loop-helix protein 1; D630008H06; I79_010155; nt-SREBP1; Processed sterol regulatory element-binding protein 1; SREBF1; SREBP1; SREBP-1; SREBP1a; SREBP-1a; SREBP1c; SREBP-1c; sterol regulatory element binding protein 1; sterol regulatory element binding protein-1; sterol regulatory element binding transcription factor 1; sterol regulatory element binding-protein 1; sterol regulatory element-binding protein 1; Sterol regulatory element-binding transcription factor 1

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20787, 6720, 78968

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P36956, P56720, Q9WTN3

Gene Symbols:
SREBF1

Immunogen:
A synthesized peptide derived from human SREBF1(Accession P36956), corresponding to amino acid residues around phosphorylated Ser396.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG