PIPA5105092

Phospho-KSR1 (Thr425) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA5105092-Each-of-1 In Stock ₹ 44,705.10

PIPA5105092 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

Phospho-KSR1 (Thr425)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

KSR1

Gene Alias

AW492498; B-KSR1; CAP kinase; D11Bhm183e; D11Bhm184e; hb; HB protein; kinase KSR1; Kinase suppressor of Ras 1; Ksr; KSR1; mKSR1; OTTHUMP00000162931; protein Hb; RSU2

Host Species

Rabbit

Purification Method

sequential chromatography

Regulatory Status

RUO

Gene ID (Entrez)

16706, 360573, 8844

Content And Storage

-20°C

Form

Liquid

Applications

Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

Q61097, Q8IVT5

Gene Symbols

KSR1

Immunogen

A synthesized peptide derived from human KSR1(Accession Q8IVT5), corresponding to amino acid residues around phosphorylated Thr425.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of KSR1 only when phosphorylated at Thr425
  • Part of a multiprotein signaling complex which promotes phosphorylation of Raf family members and activation of downstream MAP kinases
  • Independently of its kinase activity, acts as MAP2K1/MEK1 and MAP2K2/MEK2-dependent allosteric activator of BRAF; upon binding to MAP2K1/MEK1 or MAP2K2/MEK2, dimerizes with BRAF and promotes BRAF-mediated phosphorylation of MAP2K1/MEK1 and/or MAP2K2/MEK2 (PubMed:29433126)
  • Promotes activation of MAPK1 and/or MAPK3, both in response to EGF and to cAMP
  • Its kinase activity is unsure
  • Some protein kinase activity has been detected in vitro, however the physiological relevance of this activity is unknown
  • [UniProt]

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Img

Thermo Scientific

PIPA5105092

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Antigen:
Phospho-KSR1 (Thr425)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
KSR1

Gene Alias:
AW492498; B-KSR1; CAP kinase; D11Bhm183e; D11Bhm184e; hb; HB protein; kinase KSR1; Kinase suppressor of Ras 1; Ksr; KSR1; mKSR1; OTTHUMP00000162931; protein Hb; RSU2

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16706, 360573, 8844

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q61097, Q8IVT5

Gene Symbols:
KSR1

Immunogen:
A synthesized peptide derived from human KSR1(Accession Q8IVT5), corresponding to amino acid residues around phosphorylated Thr425.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5105095

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Antigen:
Phospho-PAR1 (Tyr420)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
F2R

Gene Alias:
AI482343; C HTR; Cf2r; coagulation factor II (thrombin) receptor; coagulation factor II receptor; coagulation factor II thrombin receptor; F2R; HTR; PAR1; PAR-1; protease activated receptor 1; protease-activated receptor 1; proteinase-activated receptor 1; Thrombin receptor; ThrR; TR; TRGPC

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
14062, 2149, 25439

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P25116, P26824, P30558

Gene Symbols:
F2R

Immunogen:
A synthesized peptide derived from human F2R(Accession P25116), corresponding to amino acid residues around phosphorylated Tyr420.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5105098

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Antigen:
Phospho-Naked2 (Tyr247)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Nkd2

Gene Alias:
2210403L10Rik; AW212591; Dvl-binding protein NKD2; hNkd2; mNkd2; naked cuticle 1 homolog; naked cuticle 2 homolog; naked cuticle 2 homolog (Drosophila); naked cuticle homolog 2; naked cuticle homolog 2 (Drosophila); naked cuticle-2; Naked2; naked-2; Nkd2; Protein naked cuticle homolog 2

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
308068, 72293, 85409

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q8VE28, Q969F2

Gene Symbols:
Nkd2

Immunogen:
A synthesized peptide derived from human NKD2(Accession Q969F2), corresponding to amino acid residues around phosphorylated Tyr247.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5105100

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Antigen:
Phospho-CD79b (Tyr207)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Cd79b

Gene Alias:
AGM6; B29; B-cell antigen receptor complex-associated protein beta chain; B-cell-specific glycoprotein B29; CD79; CD79b; CD79B antigen; CD79b molecule; Cd79b molecule, immunoglobulin-associated beta; Ig beta; IGB; Igbeta; Ig-beta; Immunoglobulin-associated B29 protein; immunoglobulin-associated beta; RP23-418O11.7

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
15985, 171055, 974

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P15530, P40259

Gene Symbols:
Cd79b

Immunogen:
A synthesized peptide derived from human CD79B(Accession P40259), corresponding to amino acid residues around phosphorylated Tyr207.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG