PIPA5105060
Phospho-TSC1 (Ser505) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5105060-Each-of-1 | In Stock | ₹ 43,592.82 |
PIPA5105060 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 43,592.82
GST (18%): ₹ 7,846.708
Total Price: ₹ 51,439.528
Antigen
Phospho-TSC1 (Ser505)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
TSC1
Gene Alias
hamartin; HGNC:12362; Kiaa0243; LAM; MGC86987; OTTHUMP00000022439; OTTHUMP00000198378; TSC; Tsc1; tuberous sclerosis 1; tuberous sclerosis 1 protein; Tuberous sclerosis 1 protein homolog; tumor suppressor
Host Species
Rabbit
Purification Method
sequential chromatography
Regulatory Status
RUO
Gene ID (Entrez)
60445, 64930, 7248
Content And Storage
-20°C
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
Q92574, Q9EP53, Q9Z136
Gene Symbols
TSC1
Immunogen
A synthesized peptide derived from human TSC1(Accession Q92574), corresponding to amino acid residues around phosphorylated Ser505.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of TSC1 only when phosphorylated at Ser505
- Tuberous sclerosis complex (TSC) is an autosomal dominant tumor syndrome caused by mutations in either of the TSC1 or TSC2 tumor suppressor genes
- The products of these genes form a protein complex that indirectly decreases the signaling of the mammalian Target of Rapamycin (TOR), an evolutionarily conserved serine/threonine kinase that regulates cell growth and cell cycle through its ability to integrate signals from nutrient levels and growth factors
- TOR activity is stimulated by Rheb, a member of the Ras superfamily of G-proteins, when the GTP/GDP ratio bound to Rheb is high
- Immunoprecipitated TSC1/TSC2 has been shown to stimulate Rheb GTPase activity in vitro, suggesting that the TSC1/TSC2 decreases the ability of Rheb to stimulate TOR activity
- This is supported by experiments showing overexpression of TSC1 and TSC2 results in a significant decrease in the GTP/GDP ratio bound to Rheb and the inhibition of cell growth
- A shorter 40 kDa isoform of TSC1 has been shown to exist but its function is unknown.
Compare Similar Items
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Antigen: Phospho-TSC1 (Ser505)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TSC1
Gene Alias: hamartin; HGNC:12362; Kiaa0243; LAM; MGC86987; OTTHUMP00000022439; OTTHUMP00000198378; TSC; Tsc1; tuberous sclerosis 1; tuberous sclerosis 1 protein; Tuberous sclerosis 1 protein homolog; tumor suppressor
Host Species: Rabbit
Purification Method: sequential chromatography
Regulatory Status: RUO
Gene ID (Entrez): 60445, 64930, 7248
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: Q92574, Q9EP53, Q9Z136
Gene Symbols: TSC1
Immunogen: A synthesized peptide derived from human TSC1(Accession Q92574), corresponding to amino acid residues around phosphorylated Ser505.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-TSC1 (Ser505)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TSC1
Gene Alias:
hamartin; HGNC:12362; Kiaa0243; LAM; MGC86987; OTTHUMP00000022439; OTTHUMP00000198378; TSC; Tsc1; tuberous sclerosis 1; tuberous sclerosis 1 protein; Tuberous sclerosis 1 protein homolog; tumor suppressor
Host Species:
Rabbit
Purification Method:
sequential chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
60445, 64930, 7248
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
Q92574, Q9EP53, Q9Z136
Gene Symbols:
TSC1
Immunogen:
A synthesized peptide derived from human TSC1(Accession Q92574), corresponding to amino acid residues around phosphorylated Ser505.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-CK1 alpha (Thr321)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CSNK1A1
Gene Alias: 2610208K14Rik; 4632404G05Rik; 5430427P18Rik; casein kinase 1 alpha 1; casein kinase 1 alpha 1 like; casein kinase 1 alpha 1 S homeolog; casein kinase 1 alpha 1 S homeolog; casein kinase 1, alpha 1; casein kinase 1 alpha isoform; casein kinase 1, alpha 1; casein kinase 1alpha S; casein kinase 1-alphaL; casein kinase 1-alphaLS; casein kinase I; casein kinase I alpha; casein kinase I alpha L isoform; casein kinase I alpha LS; casein kinase I alpha S; Casein kinase I isoform alpha; casein kinase I isoform alpha; casein kinase I; casein kinase I-alpha; CHUNP6894; CK I alpha; CK1; ck1 alpha; CK1a; ck1alpha; CK1alphaS; CKI alpha; CK-I alpha; CKIa; CKI-alpha; clock regulator kinase; Csnk1a; csnk1a1; CSNK1A1 protein; csnk1a1.S; CSNK1A1/CK1; CSNK1A1L; down-regulated in lung cancer; epididymis secretory sperm binding protein Li 77p; HEL-S-77p; HLCDGP1; OTTHUMP00000224000; OTTHUMP00000224001; OTTHUMP00000224003; PRO2975; protein kinase; sb:eu866; wu:fb65a02; wu:fi30h04; wu:fj19c11; XELAEV_18021437
Host Species: Rabbit
Purification Method: sequential chromatography
Regulatory Status: RUO
Gene ID (Entrez): 113927, 1452, 93687
Content And Storage: -20°C
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: P48729, P97633, Q8BK63
Gene Symbols: CSNK1A1
Immunogen: A synthesized peptide derived from human CSNK1A1(Accession P48729), corresponding to amino acid residues around phosphorylated Thr321.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-CK1 alpha (Thr321)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CSNK1A1
Gene Alias:
2610208K14Rik; 4632404G05Rik; 5430427P18Rik; casein kinase 1 alpha 1; casein kinase 1 alpha 1 like; casein kinase 1 alpha 1 S homeolog; casein kinase 1 alpha 1 S homeolog; casein kinase 1, alpha 1; casein kinase 1 alpha isoform; casein kinase 1, alpha 1; casein kinase 1alpha S; casein kinase 1-alphaL; casein kinase 1-alphaLS; casein kinase I; casein kinase I alpha; casein kinase I alpha L isoform; casein kinase I alpha LS; casein kinase I alpha S; Casein kinase I isoform alpha; casein kinase I isoform alpha; casein kinase I; casein kinase I-alpha; CHUNP6894; CK I alpha; CK1; ck1 alpha; CK1a; ck1alpha; CK1alphaS; CKI alpha; CK-I alpha; CKIa; CKI-alpha; clock regulator kinase; Csnk1a; csnk1a1; CSNK1A1 protein; csnk1a1.S; CSNK1A1/CK1; CSNK1A1L; down-regulated in lung cancer; epididymis secretory sperm binding protein Li 77p; HEL-S-77p; HLCDGP1; OTTHUMP00000224000; OTTHUMP00000224001; OTTHUMP00000224003; PRO2975; protein kinase; sb:eu866; wu:fb65a02; wu:fi30h04; wu:fj19c11; XELAEV_18021437
Host Species:
Rabbit
Purification Method:
sequential chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
113927, 1452, 93687
Content And Storage:
-20°C
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
P48729, P97633, Q8BK63
Gene Symbols:
CSNK1A1
Immunogen:
A synthesized peptide derived from human CSNK1A1(Accession P48729), corresponding to amino acid residues around phosphorylated Thr321.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-RyR3 (Ser160)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: RYR3
Gene Alias: AI851294; Brain ryanodine receptor-calcium release channel; brain-type ryanodine receptor; C230090H21; calcium release channel; HBRR; Ryanodine receptor 3; RYR3; RYR-3; Type 3 ryanodine receptor
Host Species: Rabbit
Purification Method: sequential chromatography
Regulatory Status: RUO
Gene ID (Entrez): 20192, 6263
Content And Storage: -20°C
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: A2AGL3, Q15413
Gene Symbols: RYR3
Immunogen: A synthesized peptide derived from human RYR3(Accession Q15413), corresponding to amino acid residues around phosphorylated Ser160.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-RyR3 (Ser160)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
RYR3
Gene Alias:
AI851294; Brain ryanodine receptor-calcium release channel; brain-type ryanodine receptor; C230090H21; calcium release channel; HBRR; Ryanodine receptor 3; RYR3; RYR-3; Type 3 ryanodine receptor
Host Species:
Rabbit
Purification Method:
sequential chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
20192, 6263
Content And Storage:
-20°C
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
A2AGL3, Q15413
Gene Symbols:
RYR3
Immunogen:
A synthesized peptide derived from human RYR3(Accession Q15413), corresponding to amino acid residues around phosphorylated Ser160.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-MST2 (Ser316)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: STK3
Gene Alias: 0610042I06Rik; KB-1458E12.1; KRS1; Mammalian STE20-like protein kinase 2; mess1; MST; Mst2; MST-2; MST2/C; MST2/N; Mst3; protein kinase homolog; serine/threonine kinase 3; serine/threonine kinase 3 (STE20 homolog, yeast); serine/threonine kinase 3 (Ste20, yeast homolog); serine/threonine-protein kinase 3; Serine/threonine-protein kinase 3 20kDa subunit; Serine/threonine-protein kinase 3 36kDa subunit; Serine/threonine-protein kinase Krs-1; Ste20; STE20-like kinase MST2; STK3; wu:fc19e11; zgc:55383
Host Species: Rabbit
Purification Method: sequential chromatography
Regulatory Status: RUO
Gene ID (Entrez): 56274, 65189, 6788
Content And Storage: -20°C
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: O54748, Q13188, Q9JI10
Gene Symbols: STK3
Immunogen: A synthesized peptide derived from human STK3(Accession Q13188), corresponding to amino acid residues around phosphorylated Ser316.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-MST2 (Ser316)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
STK3
Gene Alias:
0610042I06Rik; KB-1458E12.1; KRS1; Mammalian STE20-like protein kinase 2; mess1; MST; Mst2; MST-2; MST2/C; MST2/N; Mst3; protein kinase homolog; serine/threonine kinase 3; serine/threonine kinase 3 (STE20 homolog, yeast); serine/threonine kinase 3 (Ste20, yeast homolog); serine/threonine-protein kinase 3; Serine/threonine-protein kinase 3 20kDa subunit; Serine/threonine-protein kinase 3 36kDa subunit; Serine/threonine-protein kinase Krs-1; Ste20; STE20-like kinase MST2; STK3; wu:fc19e11; zgc:55383
Host Species:
Rabbit
Purification Method:
sequential chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
56274, 65189, 6788
Content And Storage:
-20°C
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
O54748, Q13188, Q9JI10
Gene Symbols:
STK3
Immunogen:
A synthesized peptide derived from human STK3(Accession Q13188), corresponding to amino acid residues around phosphorylated Ser316.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG