PIPA5105235

Phospho-RAD18 (Ser403) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA5105235-Each-of-1 In Stock ₹ 44,705.10

PIPA5105235 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

Phospho-RAD18 (Ser403)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Rad18

Gene Alias

2810024C04Rik; E3 ubiquitin-protein ligase RAD18; hHR18; hRAD18; mRAD18Sc; postreplication repair protein hRAD18p; postreplication repair protein RAD18; post-replication repair protein RAD18SC; Rad18; RAD18 E3 ubiquitin protein ligase; RAD18 homolog; RAD18 homolog (S. cerevisiae); RAD18, E3 ubiquitin protein ligase; RAD18, S. cerevisiae, homolog; Rad18sc; RING finger protein 73; RING-type E3 ubiquitin transferase RAD18; RNF73

Host Species

Rabbit

Purification Method

sequential chromatography

Regulatory Status

RUO

Gene ID (Entrez)

56852, 58186

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

Q9NS91, Q9QXK2

Gene Symbols

Rad18

Immunogen

A synthesized peptide derived from human RAD18(Accession Q9NS91), corresponding to amino acid residues around phosphorylated Ser403.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of RAD18 only when phosphorylated at Ser403
  • Human Rad18 (hRad18) is homologue of the S
  • pombe Rad18 (3,4)
  • In yeast, Rad6 and Rad18 play a crucial role in post-replication repair functions in gap-filling of a daughter strand on replication of damaged DNA (2)
  • Furthermore, Rad6-Rad18 interaction is thought to be critical at an early step during lesion bypass in yeast
  • In vivo, Rad18 protein forms a tight complex with Rad6 through a conserved ring-finger motif (3,4)
  • It has been suggested that Rad18-Rad6 complex binds to the damaged sites by the single-stranded DNA binding property of Rad 18
  • This is followed by degradation of the stalled components of DNA replication by ubiquitin-conjugating enzyme activity of Rad6 (1)
  • The human Rad18 maps on chromosome 3p24-25, the region which is often deleted in lung, breast, ovary, and testis cancers
  • The human RAD18 gene codes for a protein of 495 amino acids with a predicted molecular weight of 56 kDa
  • The human Rad18 is ubiquitously expressed in various human tissues.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA5105235

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Antigen:
Phospho-RAD18 (Ser403)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Rad18

Gene Alias:
2810024C04Rik; E3 ubiquitin-protein ligase RAD18; hHR18; hRAD18; mRAD18Sc; postreplication repair protein hRAD18p; postreplication repair protein RAD18; post-replication repair protein RAD18SC; Rad18; RAD18 E3 ubiquitin protein ligase; RAD18 homolog; RAD18 homolog (S. cerevisiae); RAD18, E3 ubiquitin protein ligase; RAD18, S. cerevisiae, homolog; Rad18sc; RING finger protein 73; RING-type E3 ubiquitin transferase RAD18; RNF73

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
56852, 58186

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q9NS91, Q9QXK2

Gene Symbols:
Rad18

Immunogen:
A synthesized peptide derived from human RAD18(Accession Q9NS91), corresponding to amino acid residues around phosphorylated Ser403.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5105236

--


Antigen:
Phospho-BABAM1 (Ser29)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
BABAM1

Gene Alias:
5430437P03Rik; BABAM1; BRCA1-A complex subunit MERIT40; BRISC and BRCA1 A complex member 1; BRISC and BRCA1-A complex member 1; C19orf62; HSPC142; mediator of Rap80 interactions and targeting 40 kDa; mediator of RAP80 interactions and targeting subunit of 40 kDa; MERIT40; NBA1; new component of the BRCA1 A complex; new component of the BRCA1-A complex; new component of the BRCAA1 A complex

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
290631, 29086, 68251

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q3UI43, Q5XIJ6, Q9NWV8

Gene Symbols:
BABAM1

Immunogen:
A synthesized peptide derived from human BABAM1(Accession Q9NWV8), corresponding to amino acid residues around phosphorylated Ser29.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5105237

--


Antigen:
Phospho-PERK (Ser1096)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
EIF2AK3

Gene Alias:
2.7.11.1; AI427929; EIF2AK3; eukaryotic translation initiation factor 2 alpha kinase 3; eukaryotic translation initiation factor 2-alpha kinase 3; HsPEK; OTTHUMP00000207187; OTTHUMP00000207188; Pancreatic eIF2-alpha kinase; PEK; Perk; PRKR-like endoplasmic reticulum kinase; WRS

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
13666, 29702, 9451

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q9NZJ5, Q9Z1Z1, Q9Z2B5

Gene Symbols:
EIF2AK3

Immunogen:
A synthesized peptide derived from human EIF2AK3(Accession Q9NZJ5), corresponding to amino acid residues around phosphorylated Ser1096.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5105238

--


Antigen:
Phospho-ALK (Tyr1096)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ALK

Gene Alias:
Alk; ALK tyrosine kinase receptor; ALK/NPM1 fusion gene; anaplastic lymphoma kinase; Anaplastic lymphoma kinase Ki1; Anaplastic Lymphoma Kinase p80; anaplastic lymphoma receptor tyrosine kinase; CD246; CD246 antigen; EC 2.7.10.1; kinase ALK; mutant anaplastic lymphoma kinase; NBLST3; npm-alk; p80; Tcrz; TFG/ALK

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11682, 238, 266802

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P97793, Q9UM73

Gene Symbols:
ALK

Immunogen:
A synthesized peptide derived from human ALK(Accession Q9UM73), corresponding to amino acid residues around phosphorylated Tyr1096.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG