PIPA5105331

Phospho-HFE2 (Ser48) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5105331-Each-of-1 In Stock ₹ 44,705.10

PIPA5105331 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

Phospho-HFE2 (Ser48)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

HFE2

Gene Alias

2310035L15Rik; 5230400G09Rik; AI414844; AI789733; DL M; DL-M; Fidgetin; haemojuvelin; HEMOCHROMATOSIS; hemochromatosis type 2 (juvenile); hemochromatosis type 2 (juvenile) (human homolog); hemochromatosis type 2 protein; Hemochromatosis type 2 protein homolog; hemojuvelin; Hemojuvelin BMP coreceptor; HFE 2; HFE2; HFE2A; HJV; JH; MGC23953; OTTHUMP00000059680; repulsive guidance molecule c; RGM C; RGM domain family member C; RGMC

Host Species

Rabbit

Purification Method

sequential chromatography

Regulatory Status

RUO

Gene ID (Entrez)

148738, 310681, 69585

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

Q6ZVN8, Q7TQ32, Q8N7M5

Gene Symbols

HFE2

Immunogen

A synthesized peptide derived from human HFE2(Accession Q6ZVN8), corresponding to amino acid residues around phosphorylated Ser48.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of HFE2 only when phosphorylated at Ser48
  • HFE2 is involved in iron metabolism
  • It may be a component of the signaling pathway which activates hepcidin or it may act as a modulator of hepcidin expression
  • It could also represent the cellular receptor for hepcidin
  • Alternatively spliced transcript variants encoding different isoforms have been identified for this gene
  • Defects in this gene are the cause of hemochromatosis type 2A, also called juvenile hemochromatosis (JH)
  • JH is an early-onset autosomal recessive disorder due to severe iron overload resulting in hypogonadotrophic hypogonadism, hepatic fibrosis or cirrhosis and cardiomyopathy, occurring typically before age of 30.

Compare Similar Items

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Img

Thermo Scientific

PIPA5105331

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Antigen:
Phospho-HFE2 (Ser48)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
HFE2

Gene Alias:
2310035L15Rik; 5230400G09Rik; AI414844; AI789733; DL M; DL-M; Fidgetin; haemojuvelin; HEMOCHROMATOSIS; hemochromatosis type 2 (juvenile); hemochromatosis type 2 (juvenile) (human homolog); hemochromatosis type 2 protein; Hemochromatosis type 2 protein homolog; hemojuvelin; Hemojuvelin BMP coreceptor; HFE 2; HFE2; HFE2A; HJV; JH; MGC23953; OTTHUMP00000059680; repulsive guidance molecule c; RGM C; RGM domain family member C; RGMC

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
148738, 310681, 69585

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q6ZVN8, Q7TQ32, Q8N7M5

Gene Symbols:
HFE2

Immunogen:
A synthesized peptide derived from human HFE2(Accession Q6ZVN8), corresponding to amino acid residues around phosphorylated Ser48.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5105333

--


Antigen:
Phospho-EED (Thr55)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
EED

Gene Alias:
EED; embryonic ectoderm development; Embryonic ectoderm development protein; ENSMUSG00000039373; HEED; l(7)5Rn; l7Rn5; lethal, Chr 7, Rinchik 5; lusk; Polycomb protein EED; WAIT1; WAIT-1; WD protein associating with integrin cytoplasmic tails 1

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
13626, 293104, 8726

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O75530, Q921E6

Gene Symbols:
EED

Immunogen:
A synthesized peptide derived from human EED(Accession O75530), corresponding to amino acid residues around phosphorylated Thr55.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5105337

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Antigen:
Phospho-PFKM (Ser74)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PFKM

Gene Alias:
6-phosphofructo-1-kinase; 6-phosphofructokinase type A; 6-phosphofructokinase, muscle type; AI131669; ATP-dependent 6-phosphofructokinase, muscle type; ATP-dependent 6-phosphofructokinase, muscle type {ECO:0000255; ATP-PFK; ATP-PFK {ECO:0000255; GSD7; HAMAP-Rule:MF_03184}; PFK; PFK1; PFK-1; Pfk4; Pfk-4; Pfka; PFK-A; PFKM; Pfk-m; PFKX; Phosphofructo-1-kinase isozyme A; phosphofructokinase 1; phosphofructokinase 4; phosphofructokinase M variant 3/4; phosphofructokinase muscle; phosphofructokinase, muscle; phosphofructokinase, polypeptide X; phosphofructokinase-1 A isozyme; phosphofructokinase-A; phosphofructokinase-M; phosphofructokinase-M (connecting peptide); phosphohexokinase; phosphohexokinase {ECO:0000255; PPP1R122; protein phosphatase 1, regulatory subunit 122

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18642, 5213, 65152

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P08237, P47857, P47858

Gene Symbols:
PFKM

Immunogen:
A synthesized peptide derived from human PFKM(Accession P08237), corresponding to amino acid residues around phosphorylated Ser74.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5105340

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Antigen:
Phospho-FKBP4 (Tyr220)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
FKBP4

Gene Alias:
51 kDa FK506-binding protein; 52 kDa FK506-binding protein; 52 kDa FKBP; 59 kDa immunophilin; 59kDa; AL022792; AW208983; FK506 binding protein 4; FK506 binding protein 4, 59kDa; FK506 binding protein 52; FK506-binding protein 4; FK506-binding protein 4 (59kD); FKBP prolyl isomerase 4; Fkbp4; FKBP-4; FKBP51; FKBP52; FKBP-52; FKBP52 protein; FKBP59; Fkpb52; HBI; HSP binding immunophilin; Hsp56; hsp90 binding protein; HSP-binding immunophilin; immunophilin FKBP52; p52; P59; p59 protein; peptidylprolyl cis-trans isomerase; peptidyl-prolyl cis-trans isomerase FKBP4; Peptidyl-prolyl cis-trans isomerase FKBP4, N-terminally processed; PPIase; PPIase FKBP4; rotamase; T-cell FK506-binding protein, 59kD

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
14228, 2288, 260321

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P30416, Q02790, Q9QVC8

Gene Symbols:
FKBP4

Immunogen:
A synthesized peptide derived from human FKBP4(Accession Q02790), corresponding to amino acid residues around phosphorylated Tyr220.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG