PIPA5105343

Phospho-TAB1 (Tyr481) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5105343-Each-of-1 In Stock ₹ 44,705.10

PIPA5105343 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

Phospho-TAB1 (Tyr481)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

TAB1

Gene Alias

2310012M03Rik; 3'-Tab1; b2b449Clo; beta activated kinase-1 binding protein-1; MAP3K7IP1; MGC57664; mitogen activated protein kinase kinase kinase 7 interacting protein 1; mitogen-activated protein kinase kinase kinase 7 interacting protein 1; mitogen-activated protein kinase kinase kinase 7-interacting protein 1; RP3-407F17.2; TAB1; TAB1beta; TAK1-binding protein 1; TGF-beta activated kinase 1/MAP3K7 binding protein 1; TGF-beta-activated kinase 1 and MAP3K7-binding protein 1; TGF-beta-activated kinase 1-binding protein 1; transforming growth factor beta-activated kinase-binding protein 1

Host Species

Rabbit

Purification Method

sequential chromatography

Regulatory Status

RUO

Gene ID (Entrez)

10454, 315139, 66513

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

Q15750, Q8CF89

Gene Symbols

TAB1

Immunogen

A synthesized peptide derived from human TAB1(Accession Q15750), corresponding to amino acid residues around phosphorylated Tyr481.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of TAB1 only when phosphorylated at Tyr481
  • TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 (TAB1) is a regulator of the MAP kinase kinase kinase MAP3K7/TAK1, which is known to mediate various intracellular signaling pathways, such as those induced by TGF beta, interleukin 1, and WNT-1
  • TAB1 interacts and thus activates TAK1 kinase
  • It has been shown that the C-terminal portion of TAB1 is sufficient for binding and activation of TAK1, while a portion of the N-terminus acts as a dominant-negative inhibitor of TGF beta, suggesting that this protein may function as a mediator between TGF beta receptors and TAK1
  • It can also interact with and activate the mitogen-activated protein kinase 14 (MAPK14/p38alpha), and thus represents an alternative activation pathway, in addition to the MAPKK pathways, which contributes to the biological responses of MAPK14 to various stimuli.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA5105343

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Antigen:
Phospho-TAB1 (Tyr481)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TAB1

Gene Alias:
2310012M03Rik; 3'-Tab1; b2b449Clo; beta activated kinase-1 binding protein-1; MAP3K7IP1; MGC57664; mitogen activated protein kinase kinase kinase 7 interacting protein 1; mitogen-activated protein kinase kinase kinase 7 interacting protein 1; mitogen-activated protein kinase kinase kinase 7-interacting protein 1; RP3-407F17.2; TAB1; TAB1beta; TAK1-binding protein 1; TGF-beta activated kinase 1/MAP3K7 binding protein 1; TGF-beta-activated kinase 1 and MAP3K7-binding protein 1; TGF-beta-activated kinase 1-binding protein 1; transforming growth factor beta-activated kinase-binding protein 1

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10454, 315139, 66513

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q15750, Q8CF89

Gene Symbols:
TAB1

Immunogen:
A synthesized peptide derived from human TAB1(Accession Q15750), corresponding to amino acid residues around phosphorylated Tyr481.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5105344

--


Antigen:
Phospho-Occludin (Tyr287)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
OCLN

Gene Alias:
AI503564; BLCPMG; Occludin; occludin 1B; Ocl; Ocln; phosphatase 1, regulatory subunit 115; PPP1R115; tight junction protein occludin; tight junction structural protein

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100506658, 18260, 83497

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q16625, Q61146, Q6P6T5

Gene Symbols:
OCLN

Immunogen:
A synthesized peptide derived from human OCLN(Accession Q16625), corresponding to amino acid residues around phosphorylated Tyr287.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5105345

--


Antigen:
Phospho-GLI1 (Thr1074)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GLI1

Gene Alias:
AV235269; GLI; GLI family zinc finger 1; Gli1; GLI-Kruppel family member GLI1; Glioma-associated oncogene; glioma-associated oncogene 1; glioma-associated oncogene homolog; glioma-associated oncogene homolog 1 (zinc finger protein); oncogene GLI; Zfp5; Zfp-5; zinc finger protein 5; zinc finger protein GLI1

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
14632, 2735

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P08151, P47806

Gene Symbols:
GLI1

Immunogen:
A synthesized peptide derived from human GLI1(Accession P08151), corresponding to amino acid residues around phosphorylated Thr1074.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5105346

--


Antigen:
Phospho-GLI1 (Ser1071)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GLI1

Gene Alias:
AV235269; GLI; GLI family zinc finger 1; Gli1; GLI-Kruppel family member GLI1; Glioma-associated oncogene; glioma-associated oncogene 1; glioma-associated oncogene homolog; glioma-associated oncogene homolog 1 (zinc finger protein); oncogene GLI; Zfp5; Zfp-5; zinc finger protein 5; zinc finger protein GLI1

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
14632, 2735

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P08151, P47806

Gene Symbols:
GLI1

Immunogen:
A synthesized peptide derived from human GLI1(Accession P08151), corresponding to amino acid residues around phosphorylated Ser1071.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG