PIPA5105473
Phospho-NPM1 (Ser10) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5105473-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA5105473 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
Phospho-NPM1 (Ser10)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
NPM1
Gene Alias
B23; B23 antibody; B23NP; MGC104254; mNPM antibody; mNPM1 antibody; NO38; NO38 antibody; Npm; npm1; npm1.L; Nucleolar phosphoprotein B23; nucleolar protein B23.1; nucleolar protein B23/No38; nucleolar protein NO38; Nucleophosmin; nucleophosmin (nucleolar phosphoprotein B23, numatrin); nucleophosmin (nucleolar phosphoprotein B23, numatrin) L homeolog; nucleophosmin 1; nucleophosmin/nucleoplasmin family, member 1; nucleoplasmin; numatrin; numatrin antibody; testicular tissue protein Li 128; unnamed protein product; XELAEV_18020022mg
Host Species
Rabbit
Purification Method
sequential chromatography
Regulatory Status
RUO
Gene ID (Entrez)
18148, 25498, 4869
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
P06748, P13084, Q61937
Gene Symbols
NPM1
Immunogen
A synthesized peptide derived from human NPM1(Accession P06748), corresponding to amino acid residues around phosphorylated Ser10.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of Nucleophosmin only when phosphorylated at Ser10
- NPM1 (Nucleophosmin 1, B23, nutramin, NO38) is a ubiquitously expressed phosphoprotein involved in ribosome assembly/transport, cytoplasmic/nuclear trafficking, regulation of DNA polymerase alpha activity, centrosome duplication, and regulation of p53
- NPM1 continuously shuttles between the nucleus, cytoplasm, nucleolus and chaperoning core histones from the nucleus to the cytoplasm
- NPM1 has been shown to bind nucleic acid, prevent protein aggregation via its chaperon activities, protect enzymes during thermal denaturation, and facilitate renaturation of chemically denatured proteins
- In its cellular structure role, there is evidence suggesting NPM1 is associated with the centrosome, and is the substrate of CDK2/cyclin E during duplication of centrosomes (cellular division)
- Due to the NPM1 gene interaction with several tumor-associated chromosome translocations, NPM1 is thought to be a portion of several fusion proteins: NPM-ALK, NPM-RAR, and NPM-MLF1
- While it is not thought to be part of the transforming potential of these fusion proteins, NPM1 is believed to act as the interface for oligomerization and oncogenic conversion of these tumor promoting fusion proteins
- Further, NPM1 is also known to sequester the tumor suppressor RF in the nucleolus, protecting it from degradation until it is necessary
- Dysfunction of the NPM1 protein is associated with diseases such as acute myeloid leukemia and lymphomatoid papulosis.
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Antigen: Phospho-NPM1 (Ser10)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: NPM1
Gene Alias: B23; B23 antibody; B23NP; MGC104254; mNPM antibody; mNPM1 antibody; NO38; NO38 antibody; Npm; npm1; npm1.L; Nucleolar phosphoprotein B23; nucleolar protein B23.1; nucleolar protein B23/No38; nucleolar protein NO38; Nucleophosmin; nucleophosmin (nucleolar phosphoprotein B23, numatrin); nucleophosmin (nucleolar phosphoprotein B23, numatrin) L homeolog; nucleophosmin 1; nucleophosmin/nucleoplasmin family, member 1; nucleoplasmin; numatrin; numatrin antibody; testicular tissue protein Li 128; unnamed protein product; XELAEV_18020022mg
Host Species: Rabbit
Purification Method: sequential chromatography
Regulatory Status: RUO
Gene ID (Entrez): 18148, 25498, 4869
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: P06748, P13084, Q61937
Gene Symbols: NPM1
Immunogen: A synthesized peptide derived from human NPM1(Accession P06748), corresponding to amino acid residues around phosphorylated Ser10.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-NPM1 (Ser10)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
NPM1
Gene Alias:
B23; B23 antibody; B23NP; MGC104254; mNPM antibody; mNPM1 antibody; NO38; NO38 antibody; Npm; npm1; npm1.L; Nucleolar phosphoprotein B23; nucleolar protein B23.1; nucleolar protein B23/No38; nucleolar protein NO38; Nucleophosmin; nucleophosmin (nucleolar phosphoprotein B23, numatrin); nucleophosmin (nucleolar phosphoprotein B23, numatrin) L homeolog; nucleophosmin 1; nucleophosmin/nucleoplasmin family, member 1; nucleoplasmin; numatrin; numatrin antibody; testicular tissue protein Li 128; unnamed protein product; XELAEV_18020022mg
Host Species:
Rabbit
Purification Method:
sequential chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
18148, 25498, 4869
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
P06748, P13084, Q61937
Gene Symbols:
NPM1
Immunogen:
A synthesized peptide derived from human NPM1(Accession P06748), corresponding to amino acid residues around phosphorylated Ser10.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-beta-2 Adrenergic Receptor (Thr68)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Adrb2
Gene Alias: Adrb2; Adrb-2; ADRB2R; ADRBR; Adrenergic beta 2- receptor surface; adrenergic receptor beta 2; adrenergic receptor, beta 2; adrenergic, beta-2, receptor, surface; adrenergic, beta-2-, receptor, surface; adrenoceptor beta 2; adrenoceptor beta 2 surface; adrenoceptor beta 2, surface; AR beta2; B2AR; Badm; BAR; beta 2-AR; beta-2 adrenergic receptor; Beta-2 adrenoceptor; beta-2 adrenoreceptor; beta-2-adrenergic receptor; beta2-adrenergic receptor; beta2-Adrenoreceptor; BETA2AR; catecholamine receptor; Gpcr7; HGNC:286
Host Species: Rabbit
Purification Method: sequential chromatography
Regulatory Status: RUO
Gene ID (Entrez): 11555, 154, 24176
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: P07550, P10608, P18762
Gene Symbols: Adrb2
Immunogen: A synthesized peptide derived from human ADRB2(Accession P07550), corresponding to amino acid residues around phosphorylated Thr68.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-beta-2 Adrenergic Receptor (Thr68)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Adrb2
Gene Alias:
Adrb2; Adrb-2; ADRB2R; ADRBR; Adrenergic beta 2- receptor surface; adrenergic receptor beta 2; adrenergic receptor, beta 2; adrenergic, beta-2, receptor, surface; adrenergic, beta-2-, receptor, surface; adrenoceptor beta 2; adrenoceptor beta 2 surface; adrenoceptor beta 2, surface; AR beta2; B2AR; Badm; BAR; beta 2-AR; beta-2 adrenergic receptor; Beta-2 adrenoceptor; beta-2 adrenoreceptor; beta-2-adrenergic receptor; beta2-adrenergic receptor; beta2-Adrenoreceptor; BETA2AR; catecholamine receptor; Gpcr7; HGNC:286
Host Species:
Rabbit
Purification Method:
sequential chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
11555, 154, 24176
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
P07550, P10608, P18762
Gene Symbols:
Adrb2
Immunogen:
A synthesized peptide derived from human ADRB2(Accession P07550), corresponding to amino acid residues around phosphorylated Thr68.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-HSP90 alpha (Tyr197)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Hsp90aa1
Gene Alias: 86kDa; 89kDa; 90-kDa heat shock protein; 90-kDa heat shock protein alpha; akineto; AL024080; AL024147; EL52; epididymis luminal secretory protein 52; epididymis secretory sperm binding protein Li 65p; fb17b01; heat shock 86 kDa; heat shock 90kD protein 1, alpha; heat shock 90kD protein 1, alpha-like 4; heat shock 90kD protein, alpha-like 4; heat shock 90kDa protein 1, alpha; heat shock 90kDa protein 1, beta; Heat shock protein; heat shock protein 1, alpha; heat shock protein 86; heat shock protein 90; heat shock protein 90 alpha family class A member 1; heat shock protein 90, alpha (cytosolic), class A member 1; heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 1; heat shock protein 90-alpha 1; heat shock protein 90kDa alpha (cytosolic), class A member 1; heat shock protein 90kDa alpha family class A member 1; heat shock protein alpha; Heat shock protein HSP 90-alpha; Heat shock protein HSP 90-alpha 1; heat shock protein HSP90 alpha; heat shock protein hsp90a
Host Species: Rabbit
Purification Method: sequential chromatography
Regulatory Status: RUO
Gene ID (Entrez): 15519, 299331, 3320
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: P07900, P07901, P82995
Gene Symbols: Hsp90aa1
Immunogen: A synthesized peptide derived from human HSP90AA1(Accession P07900), corresponding to amino acid residues around phosphorylated Tyr197.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-HSP90 alpha (Tyr197)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Hsp90aa1
Gene Alias:
86kDa; 89kDa; 90-kDa heat shock protein; 90-kDa heat shock protein alpha; akineto; AL024080; AL024147; EL52; epididymis luminal secretory protein 52; epididymis secretory sperm binding protein Li 65p; fb17b01; heat shock 86 kDa; heat shock 90kD protein 1, alpha; heat shock 90kD protein 1, alpha-like 4; heat shock 90kD protein, alpha-like 4; heat shock 90kDa protein 1, alpha; heat shock 90kDa protein 1, beta; Heat shock protein; heat shock protein 1, alpha; heat shock protein 86; heat shock protein 90; heat shock protein 90 alpha family class A member 1; heat shock protein 90, alpha (cytosolic), class A member 1; heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 1; heat shock protein 90-alpha 1; heat shock protein 90kDa alpha (cytosolic), class A member 1; heat shock protein 90kDa alpha family class A member 1; heat shock protein alpha; Heat shock protein HSP 90-alpha; Heat shock protein HSP 90-alpha 1; heat shock protein HSP90 alpha; heat shock protein hsp90a
Host Species:
Rabbit
Purification Method:
sequential chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
15519, 299331, 3320
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
P07900, P07901, P82995
Gene Symbols:
Hsp90aa1
Immunogen:
A synthesized peptide derived from human HSP90AA1(Accession P07900), corresponding to amino acid residues around phosphorylated Tyr197.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-IGF1R alpha (Thr1163)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Igf1r
Gene Alias: A330103N21Rik; CD221; D930020L01; hyft; IGF-1 receptor; Igf1r; IGF-1R; IGF-I receptor; IGFIR; IGFIRC; IGFR; Igfr1; insulin like growth factor 1 receptor; insulin-like growth factor 1 receptor; Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain; insulin-like growth factor 1 receptor beta subunit; insulin-like growth factor I receptor; insulin-like growth factor receptor 1; insulin-like growth factor-I receptor; insulin-like growth factor-I receptor precursor; JTK13; line 186; soluble IGF1R variant 1; soluble IGF1R variant 2
Host Species: Rabbit
Purification Method: sequential chromatography
Regulatory Status: RUO
Gene ID (Entrez): 16001, 25718, 3480
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: P08069, P24062, Q60751
Gene Symbols: Igf1r
Immunogen: A synthesized peptide derived from human IGF1R(Accession P08069), corresponding to amino acid residues around phosphorylated Thr1163.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-IGF1R alpha (Thr1163)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Igf1r
Gene Alias:
A330103N21Rik; CD221; D930020L01; hyft; IGF-1 receptor; Igf1r; IGF-1R; IGF-I receptor; IGFIR; IGFIRC; IGFR; Igfr1; insulin like growth factor 1 receptor; insulin-like growth factor 1 receptor; Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain; insulin-like growth factor 1 receptor beta subunit; insulin-like growth factor I receptor; insulin-like growth factor receptor 1; insulin-like growth factor-I receptor; insulin-like growth factor-I receptor precursor; JTK13; line 186; soluble IGF1R variant 1; soluble IGF1R variant 2
Host Species:
Rabbit
Purification Method:
sequential chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
16001, 25718, 3480
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
P08069, P24062, Q60751
Gene Symbols:
Igf1r
Immunogen:
A synthesized peptide derived from human IGF1R(Accession P08069), corresponding to amino acid residues around phosphorylated Thr1163.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG