PIPA5105507

Phospho-PLCG2 (Tyr1245) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5105507-Each-of-1 In Stock ₹ 43,592.82

PIPA5105507 - Each of 1

₹ 43,592.82

In Stock

Quantity

1

Base Price: ₹ 43,592.82

GST (18%): ₹ 7,846.708

Total Price: ₹ 51,439.528

Antigen

Phospho-PLCG2 (Tyr1245)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Plcg2

Gene Alias

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2; APLAID; FCAS3; phosphoinositide phospholipase C; phosphoinositide phospholipase C-gamma-2; phospholipase C gamma 2; phospholipase C, gamma 2; phospholipase C, gamma 2 (phosphatidylinositol-specific); phospholipase C-gamma-2; Phospholipase C-IV; PLC gamma 2; PLC gamma2; PLC- gamma2; PLC gamma-2; PLCG2; Plcg-2; PLC-gamma; PLCgamma2; PLC-gamma-2; PLC-IV

Host Species

Rabbit

Purification Method

sequential chromatography

Regulatory Status

RUO

Gene ID (Entrez)

234779, 29337, 5336

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

P16885, P24135, Q8CIH5

Gene Symbols

Plcg2

Immunogen

A synthesized peptide derived from human PLCG2(Accession P16885), corresponding to amino acid residues around phosphorylated Tyr1245.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of PLCG2 only when phosphorylated at Tyr1245
  • Phosphoinositide-specific phospholipase C (PLC) plays a crucial role in the initiation of receptor mediated signal transduction through the generation of the two second messengers, inositol 1,4,5-triphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate
  • There are many mammalian PLC isozymes, including PLC beta1, PLC beta2, PLC beta3, PLC beta4, PLC gamma1, PLC gamma2, PLC delta1, PLC delta2 and PLCe
  • PLC delta exists as four different isoforms
  • PLC delta1, a calcium signal amplifier, is activated by an atypical GTP-binding protein
  • In addition, PLC delta1 is an effector for GTP-binding protein transglutaminase II-mediated oxytocin receptor and alpha1B-adrenoreceptor signaling
  • Mouse PLC delta1 is highly expressed in brain, heart, lung and testis
  • PLC delta is abnormally accumulated in autopsied brains with Alzheimer's disease (AD), suggesting that it may play a role in the pathology of AD
  • PLC delta2 is markedly expressed in type II intestinal metaplasia and in the adenocarcinoma
  • When PLC delta2 is expressed in type I intestinal metaplasia, the metaplasia is generally considered benignant, yet evolves toward neoplastic transformation
  • Thus, PLC delta2 expression may be a possible marker of gastric malignant transformation.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA5105507

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Antigen:
Phospho-PLCG2 (Tyr1245)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Plcg2

Gene Alias:
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2; APLAID; FCAS3; phosphoinositide phospholipase C; phosphoinositide phospholipase C-gamma-2; phospholipase C gamma 2; phospholipase C, gamma 2; phospholipase C, gamma 2 (phosphatidylinositol-specific); phospholipase C-gamma-2; Phospholipase C-IV; PLC gamma 2; PLC gamma2; PLC- gamma2; PLC gamma-2; PLCG2; Plcg-2; PLC-gamma; PLCgamma2; PLC-gamma-2; PLC-IV

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
234779, 29337, 5336

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P16885, P24135, Q8CIH5

Gene Symbols:
Plcg2

Immunogen:
A synthesized peptide derived from human PLCG2(Accession P16885), corresponding to amino acid residues around phosphorylated Tyr1245.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA5105509

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Antigen:
Phospho-PKC alpha (Tyr195)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PRKCA

Gene Alias:
AAG6; aging-associated gene 6; AI875142; EC 2.7.11.13; FHC; FTH; FTHL6; im:7139045; kinase PKC-alpha; KPCA; MGC104426; PIG15; PKC III; Pkca; PKC-A; PKC-alpha; PKC-III; PKRCA; PLIF; PRKACA; Prkca; prkcaa; protein kinase C; protein kinase C alpha; protein kinase C alpha type; protein kinase C alpha type; protein kinase C, alpha, a; protein kinase C, alpha; protein kinase C, alpha, a; protein kinase c-alpha; si:dkey-8l19.1; Unknown (protein for IMAGE:7139045); unnamed protein product

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18750, 24680, 5578

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P05696, P17252, P20444

Gene Symbols:
PRKCA

Immunogen:
A synthesized peptide derived from human PRKCA(Accession P17252), corresponding to amino acid residues around phosphorylated Tyr195.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA5105511

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Antigen:
Phospho-JunB (Ser259)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Junb

Gene Alias:
activator protein 1; AP-1; Jun B; jun B proto-oncogene; Junb; Jun-b; Jun-B oncogene; JunB proto-oncogene, AP-1 transcription factor subunit; myD21; Oncogene Jun-B; Transcription factor jun-B

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16477, 24517, 3726

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P09450, P17275, P24898

Gene Symbols:
Junb

Immunogen:
A synthesized peptide derived from human JUNB(Accession P17275), corresponding to amino acid residues around phosphorylated Ser259.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA5105514

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Antigen:
Phospho-Synapsin 1 (Ser427)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SYN1

Gene Alias:
Brain protein 4.1; SYN1; Syn-1; SYN1a; SYN1b; Syn1-S; synapsin 1; synapsin I; synapsin Ia; synapsin Ib; synapsin-1; SYNI; truncated synapsin 1-S

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20964, 24949, 6853

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O88935, P09951, P17600

Gene Symbols:
SYN1

Immunogen:
A synthesized peptide derived from human SYN1(Accession P17600), corresponding to amino acid residues around phosphorylated Ser427.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG