PIPA5105528
Phospho-ErbB3 (Ser686) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5105528-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA5105528 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
Phospho-ErbB3 (Ser686)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
ERBB3
Gene Alias
avian erythroblastosis oncogene B 3; avian erythroblastosis oncogene B 3 receptor; C76256; c-erbB3; c-erbB-3; C-errB-3; erb-b2 receptor tyrosine kinase 3; ERBB3; Erbb-3; Erbb3r; erbB3-S; glial growth factor receptor; HER3; human epidermal growth factor receptor 3; LCCS2; MDA BF 1; MDA-BF-1; MGC88033; nuc-ErbB3; p180 ErbB3; p180-ErbB3; p45 sErbB3; p45-sErbB3; p85 sErbB3; p85-sErbB3; proto-oncogene-like protein c-ErbB-3; receptor tyrosine kinase; receptor tyrosine-protein kinase erbB-3; receptor tyrosine-protein kinase erbB-3; LOW QUALITY PROTEIN: receptor tyrosine-protein kinase erbB-3; tyrosine kinase-type cell surface receptor HER3; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3; v-erb-b2 erythroblastic leukemia viral oncogene homolog 3; v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)
Host Species
Rabbit
Purification Method
sequential chromatography
Regulatory Status
RUO
Gene ID (Entrez)
13867, 2065, 29496
Content And Storage
-20°C
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
P21860, Q61526, Q62799
Gene Symbols
ERBB3
Immunogen
A synthesized peptide derived from human ERBB3(Accession P21860), corresponding to amino acid residues around phosphorylated Ser686.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of HER3/ErbB3 only when phosphorylated at Ser686
- ErbB3 (c-erbB-3/HER-3) is a member of the type I family of growth factor receptors and binds to ligands in the heregulin family
- ErbB3 is over-expressed in a variety of tumors in the prostate, bladder, breast, stomach, pancreas, and colon
- Heregulin and EGF stimulate tyrosine phosphorylation of c-erbB-3 to different extents
- The ErbB3 gene is located on the long arm of human chromosome 12 (12q13) and is transcribed into a 6
- 2kb mRNA which is translated into a 160/180 kDa glycoprotein
- The ErbB3 gene encodes a transmembrane receptor tyrosine kinase due to alternative splicing and forms heterodimers with other EGF receptor family members that have kinase activity
- Heterodimerization leads to the activation of pathways that lead to cell proliferation or differentiation
- Alternate transcriptional splice variants encoding different isoforms of ErbB3 have been characterized
- One ErbB3 isoform lacks the intermembrane region, is secreted outside the cell, and acts to modulate the activity of the membrane-bound form
- Additional splice variants have also been reported, but they have not been thoroughly characterized.
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Antigen: Phospho-ErbB3 (Ser686)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ERBB3
Gene Alias: avian erythroblastosis oncogene B 3; avian erythroblastosis oncogene B 3 receptor; C76256; c-erbB3; c-erbB-3; C-errB-3; erb-b2 receptor tyrosine kinase 3; ERBB3; Erbb-3; Erbb3r; erbB3-S; glial growth factor receptor; HER3; human epidermal growth factor receptor 3; LCCS2; MDA BF 1; MDA-BF-1; MGC88033; nuc-ErbB3; p180 ErbB3; p180-ErbB3; p45 sErbB3; p45-sErbB3; p85 sErbB3; p85-sErbB3; proto-oncogene-like protein c-ErbB-3; receptor tyrosine kinase; receptor tyrosine-protein kinase erbB-3; receptor tyrosine-protein kinase erbB-3; LOW QUALITY PROTEIN: receptor tyrosine-protein kinase erbB-3; tyrosine kinase-type cell surface receptor HER3; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3; v-erb-b2 erythroblastic leukemia viral oncogene homolog 3; v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)
Host Species: Rabbit
Purification Method: sequential chromatography
Regulatory Status: RUO
Gene ID (Entrez): 13867, 2065, 29496
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: P21860, Q61526, Q62799
Gene Symbols: ERBB3
Immunogen: A synthesized peptide derived from human ERBB3(Accession P21860), corresponding to amino acid residues around phosphorylated Ser686.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-ErbB3 (Ser686)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ERBB3
Gene Alias:
avian erythroblastosis oncogene B 3; avian erythroblastosis oncogene B 3 receptor; C76256; c-erbB3; c-erbB-3; C-errB-3; erb-b2 receptor tyrosine kinase 3; ERBB3; Erbb-3; Erbb3r; erbB3-S; glial growth factor receptor; HER3; human epidermal growth factor receptor 3; LCCS2; MDA BF 1; MDA-BF-1; MGC88033; nuc-ErbB3; p180 ErbB3; p180-ErbB3; p45 sErbB3; p45-sErbB3; p85 sErbB3; p85-sErbB3; proto-oncogene-like protein c-ErbB-3; receptor tyrosine kinase; receptor tyrosine-protein kinase erbB-3; receptor tyrosine-protein kinase erbB-3; LOW QUALITY PROTEIN: receptor tyrosine-protein kinase erbB-3; tyrosine kinase-type cell surface receptor HER3; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3; v-erb-b2 erythroblastic leukemia viral oncogene homolog 3; v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)
Host Species:
Rabbit
Purification Method:
sequential chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
13867, 2065, 29496
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
P21860, Q61526, Q62799
Gene Symbols:
ERBB3
Immunogen:
A synthesized peptide derived from human ERBB3(Accession P21860), corresponding to amino acid residues around phosphorylated Ser686.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-ErbB3 (Tyr1197)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ERBB3
Gene Alias: avian erythroblastosis oncogene B 3; avian erythroblastosis oncogene B 3 receptor; C76256; c-erbB3; c-erbB-3; C-errB-3; erb-b2 receptor tyrosine kinase 3; ERBB3; Erbb-3; Erbb3r; erbB3-S; glial growth factor receptor; HER3; human epidermal growth factor receptor 3; LCCS2; MDA BF 1; MDA-BF-1; MGC88033; nuc-ErbB3; p180 ErbB3; p180-ErbB3; p45 sErbB3; p45-sErbB3; p85 sErbB3; p85-sErbB3; proto-oncogene-like protein c-ErbB-3; receptor tyrosine kinase; receptor tyrosine-protein kinase erbB-3; receptor tyrosine-protein kinase erbB-3; LOW QUALITY PROTEIN: receptor tyrosine-protein kinase erbB-3; tyrosine kinase-type cell surface receptor HER3; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3; v-erb-b2 erythroblastic leukemia viral oncogene homolog 3; v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)
Host Species: Rabbit
Purification Method: sequential chromatography
Regulatory Status: RUO
Gene ID (Entrez): 13867, 2065, 29496
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: P21860, Q61526, Q62799
Gene Symbols: ERBB3
Immunogen: A synthesized peptide derived from human ERBB3(Accession P21860), corresponding to amino acid residues around phosphorylated Tyr1197.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-ErbB3 (Tyr1197)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ERBB3
Gene Alias:
avian erythroblastosis oncogene B 3; avian erythroblastosis oncogene B 3 receptor; C76256; c-erbB3; c-erbB-3; C-errB-3; erb-b2 receptor tyrosine kinase 3; ERBB3; Erbb-3; Erbb3r; erbB3-S; glial growth factor receptor; HER3; human epidermal growth factor receptor 3; LCCS2; MDA BF 1; MDA-BF-1; MGC88033; nuc-ErbB3; p180 ErbB3; p180-ErbB3; p45 sErbB3; p45-sErbB3; p85 sErbB3; p85-sErbB3; proto-oncogene-like protein c-ErbB-3; receptor tyrosine kinase; receptor tyrosine-protein kinase erbB-3; receptor tyrosine-protein kinase erbB-3; LOW QUALITY PROTEIN: receptor tyrosine-protein kinase erbB-3; tyrosine kinase-type cell surface receptor HER3; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3; v-erb-b2 erythroblastic leukemia viral oncogene homolog 3; v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)
Host Species:
Rabbit
Purification Method:
sequential chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
13867, 2065, 29496
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
P21860, Q61526, Q62799
Gene Symbols:
ERBB3
Immunogen:
A synthesized peptide derived from human ERBB3(Accession P21860), corresponding to amino acid residues around phosphorylated Tyr1197.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-FGFR4 (Tyr642)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Fgfr4
Gene Alias: CD334; CTLA-2-beta protein; FGF Receptor 4; Fgfr4; FGFR-4; Fibroblast growth factor receptor 4; fibroblast growth factor receptor 4 16 minus form; hydroxyaryl-protein kinase; JTK2; MGC20292; Mpk-11; protein-tyrosine kinase; protein-tyrosine kinase receptor MPK-11; TKF; tyrosine kinase related to fibroblast growth factor receptor; tyrosylprotein kinase
Host Species: Rabbit
Purification Method: sequential chromatography
Regulatory Status: RUO
Gene ID (Entrez): 14186, 2264, 25114
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: P22455, Q03142, Q498D6
Gene Symbols: Fgfr4
Immunogen: A synthesized peptide derived from human FGFR4(Accession P22455), corresponding to amino acid residues around phosphorylated Tyr642.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-FGFR4 (Tyr642)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Fgfr4
Gene Alias:
CD334; CTLA-2-beta protein; FGF Receptor 4; Fgfr4; FGFR-4; Fibroblast growth factor receptor 4; fibroblast growth factor receptor 4 16 minus form; hydroxyaryl-protein kinase; JTK2; MGC20292; Mpk-11; protein-tyrosine kinase; protein-tyrosine kinase receptor MPK-11; TKF; tyrosine kinase related to fibroblast growth factor receptor; tyrosylprotein kinase
Host Species:
Rabbit
Purification Method:
sequential chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
14186, 2264, 25114
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
P22455, Q03142, Q498D6
Gene Symbols:
Fgfr4
Immunogen:
A synthesized peptide derived from human FGFR4(Accession P22455), corresponding to amino acid residues around phosphorylated Tyr642.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-JAK1 (Tyr1125)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: JAK1
Gene Alias: AA960307; BAP004; C130039L05Rik; EC 2.7.10.2; Jak1; JAK-1; JAK1A; JAK1B; Janus kinase 1; Janus protein tyrosine kinase 1; JTK3; kinase Jak1; Tyrosine-protein kinase JAK1
Host Species: Rabbit
Purification Method: sequential chromatography
Regulatory Status: RUO
Gene ID (Entrez): 16451, 3716, 84598
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: P23458, P52332
Gene Symbols: JAK1
Immunogen: A synthesized peptide derived from human JAK1(Accession P23458), corresponding to amino acid residues around phosphorylated Tyr1125.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-JAK1 (Tyr1125)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
JAK1
Gene Alias:
AA960307; BAP004; C130039L05Rik; EC 2.7.10.2; Jak1; JAK-1; JAK1A; JAK1B; Janus kinase 1; Janus protein tyrosine kinase 1; JTK3; kinase Jak1; Tyrosine-protein kinase JAK1
Host Species:
Rabbit
Purification Method:
sequential chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
16451, 3716, 84598
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
P23458, P52332
Gene Symbols:
JAK1
Immunogen:
A synthesized peptide derived from human JAK1(Accession P23458), corresponding to amino acid residues around phosphorylated Tyr1125.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG