PIPA5106085

Phospho-ErbB4 (Tyr1056) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5106085-Each-of-1 In Stock ₹ 44,705.10

PIPA5106085 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

Phospho-ErbB4 (Tyr1056)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ERBB4

Gene Alias

4ICD; ALS19; avian erythroblastic leukemia viral (v-erb-b2) oncogene homolog 4; avian erythroblastosis oncogene B 4; c-erbB-4; erb-b2 receptor tyrosine kinase 4; Erbb4; ERBB4 intracellular domain; ERBB4 transcript variant I12DEL; ERBB4 transcript variant I20DEL; Her4; human epidermal growth factor receptor 4; Mer4; OTTHUMP00000209432; p180erbB4; proto-oncogene-like protein c-ErbB-4; receptor tyrosine kinase; receptor tyrosine-protein kinase erbB-4; s80HER4; Tyro-2; Tyrosine kinase-type cell surface receptor HER4; v-erb-a erythroblastic leukemia viral oncogene homolog 4; v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian); v-erb-b2 avian erythroblastic leukemia viral oncogene 4; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4

Host Species

Rabbit

Purification Method

sequential chromatography

Regulatory Status

RUO

Gene ID (Entrez)

13869, 2066, 59323

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

Q15303, Q61527, Q62956

Gene Symbols

ERBB4

Immunogen

A synthesized peptide derived from human ERBB4(Accession Q15303), corresponding to amino acid residues around phosphorylated Tyr1056.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Related Products

Img

Thermo Scientific

PIPA5106143

--

Img

Thermo Scientific

PIPA5105792

--

Img

Thermo Scientific

PIPA5105529

--

Img

Thermo Scientific

PIPA5105528

--

Img

Thermo Scientific

PIPA5105790

--

Img

Thermo Scientific

PIPA5105791

--

Img

Thermo Scientific

PIPA5106145

--

Img

Thermo Scientific

PIPA5105915

--

Description

  • Antibody detects endogenous levels of HER4 only when phosphorylated at Tyr1056
  • Oncogene ERBB4 (HER4) is a member of the type I receptor protein tyrosine subfamily that includes EGFR, ERBB2, and ERBB3
  • ERBB4 binds and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation
  • ErbB 4 is activated by neuregulins and NTAK (neural and thymus derived activator for ErbB kinases)
  • ErbB 4 is a receptor for heregulin and is capable of mediating HGL-stimulated tyrosine phosphorylation of itself
  • Like other protein kinases, ErbB 4 mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation
  • ErbB 4 is most predominantly expressed in several breast carcinoma cell lines, and in normal skeletal muscle, heart, pituitary, brain, and cerebellum
  • Breast tumor cell lines T47-D, MDA-MB-453, BT-474 and H3396 are found to have the highest levels of mRNA, and intermediate levels are seen in MCF-7, MDAMB-330 and MDA-MB-361
  • Expression of ErbB 4 is low or absent in some breast tumor cell lines such as MDA-MB-231, MDA-MB-157, MDA-MB-468, and SKBR-3
  • ErbB 4 levels have been found to be elevated in certain human tumor cell lines suggesting that it may play a role in some malignancies.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA5106085

--


Antigen:
Phospho-ErbB4 (Tyr1056)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ERBB4

Gene Alias:
4ICD; ALS19; avian erythroblastic leukemia viral (v-erb-b2) oncogene homolog 4; avian erythroblastosis oncogene B 4; c-erbB-4; erb-b2 receptor tyrosine kinase 4; Erbb4; ERBB4 intracellular domain; ERBB4 transcript variant I12DEL; ERBB4 transcript variant I20DEL; Her4; human epidermal growth factor receptor 4; Mer4; OTTHUMP00000209432; p180erbB4; proto-oncogene-like protein c-ErbB-4; receptor tyrosine kinase; receptor tyrosine-protein kinase erbB-4; s80HER4; Tyro-2; Tyrosine kinase-type cell surface receptor HER4; v-erb-a erythroblastic leukemia viral oncogene homolog 4; v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian); v-erb-b2 avian erythroblastic leukemia viral oncogene 4; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
13869, 2066, 59323

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q15303, Q61527, Q62956

Gene Symbols:
ERBB4

Immunogen:
A synthesized peptide derived from human ERBB4(Accession Q15303), corresponding to amino acid residues around phosphorylated Tyr1056.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5106086

--


Antigen:
Phospho-GABBR2 (Ser884)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GABBR2

Gene Alias:
FLJ36928; G protein-coupled receptor 51; GABA BR; GABA-B R2 receptor; GABA-B receptor 2; GABA-B receptor, R2 subunit; GABABR2; GABA-BR2; GABA-B-R2; Gabbr2; gamma-aminobutyric acid; gamma-aminobutyric acid (GABA) B receptor 2; gamma-aminobutyric acid (GABA) B receptor, 2; gamma-aminobutyric acid B receptor 2; gamma-aminobutyric acid type B receptor subunit 2; gamma-aminobutyric acid type B receptor, subunit 2; gb2; Gm425; Gpr51; GPRC3B; G-protein coupled receptor 51; HG20; HRIHFB2099; MGC119386; MGC119388; MGC119389; ortholog of human G protein-coupled receptor 51 GPR51; RP23-337N2.1

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
242425, 83633, 9568

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O75899, O88871, Q80T41

Gene Symbols:
GABBR2

Immunogen:
A synthesized peptide derived from human GABBR2(Accession O75899), corresponding to amino acid residues around phosphorylated Ser884.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5106089

--


Antigen:
Phospho-GRK2 (Tyr86)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GRK2

Gene Alias:
ADRBK1; Adrbk-1; adrenergic beta receptor kinase 1; adrenergic receptor kinase, beta 1; adrenergic, beta, receptor kinase 1; BARK; BARK1; Bark-1; beta ARK; Beta-adrenergic receptor kinase 1; beta-adrenergic receptor kinase 1 beta ARK1; beta-AR kinase-1; betaARK1; BETA-ARK1; beta-ARK-1; EC 2.7.1.126; G protein-coupled receptor kinase 2; G-protein coupled receptor kinase 2; G-protein-coupled receptor kinase 2; grk 2; Grk2; GRK-2

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
110355, 156, 25238

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P25098, P26817, Q99MK8

Gene Symbols:
GRK2

Immunogen:
A synthesized peptide derived from human GRK2(Accession P25098), corresponding to amino acid residues around phosphorylated Tyr86.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5106090

--


Antigen:
Phospho-HDAC7 (Ser486)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
HDAC7

Gene Alias:
5830434K02Rik; HD7; HD7a; hdac4l; Hdac7; hdac-7; Hdac7a; histone deacetylase 7; Histone deacetylase 7A; mFLJ00062

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
51564, 56233

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q8C2B3, Q8WUI4

Gene Symbols:
HDAC7

Immunogen:
A synthesized peptide derived from human HDAC7(Accession Q8WUI4), corresponding to amino acid residues around phosphorylated Ser486.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG