PIPA5105691

Phospho-NEDD4L (Ser479) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA5105691-Each-of-1 In Stock ₹ 44,705.10

PIPA5105691 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

Phospho-NEDD4L (Ser479)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

NEDD4L

Gene Alias

1300012C07Rik; E3 ubiquitin-protein ligase NEDD4-like; FLJ33870; HECT-type E3 ubiquitin transferase NED4L; hNEDD4-2; KIAA0439; NEDD4; NEDD4 like E3 ubiquitin protein ligase; NEDD4.2; Nedd4-2; nedd4b; NEDD4L; NEDL3; neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase; neural precursor cell expressed, developmentally down-regulated gene 4b; neural precursor cell expressed, developmentally down-regulated gene 4-like; RSP5; ubiquitin-protein ligase Nedd4-2; ubiquitin-protein ligase Rsp5; Unknown (protein for IMAGE:7986262)

Host Species

Rabbit

Purification Method

sequential chromatography

Regulatory Status

RUO

Gene ID (Entrez)

23327, 291553

Content And Storage

-20°C

Form

Liquid

Applications

Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

Q96PU5

Gene Symbols

NEDD4L

Immunogen

A synthesized peptide derived from human NEDD4L(Accession Q96PU5), corresponding to amino acid residues around phosphorylated Ser479.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of NEDD4L only when phosphorylated at Ser479
  • NEDD4L is an E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates
  • NEDD4L inhibits TGF-beta signaling by triggering SMAD2 and TGFR1 ubiquitination and proteasome-dependent degradation
  • NEDD4L promotes ubiquitination and internalization of various plasma membrane channels such as ENaC, Nav1.2, Nav1.3, Nav1.5, Nav1.7, Nav1.8, Kv1.3, EAAT1 or CLC5
  • NEDD4L also promotes ubiquitination and degradation of SGK.

Compare Similar Items

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Thermo Scientific

PIPA5105691

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Antigen:
Phospho-NEDD4L (Ser479)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NEDD4L

Gene Alias:
1300012C07Rik; E3 ubiquitin-protein ligase NEDD4-like; FLJ33870; HECT-type E3 ubiquitin transferase NED4L; hNEDD4-2; KIAA0439; NEDD4; NEDD4 like E3 ubiquitin protein ligase; NEDD4.2; Nedd4-2; nedd4b; NEDD4L; NEDL3; neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase; neural precursor cell expressed, developmentally down-regulated gene 4b; neural precursor cell expressed, developmentally down-regulated gene 4-like; RSP5; ubiquitin-protein ligase Nedd4-2; ubiquitin-protein ligase Rsp5; Unknown (protein for IMAGE:7986262)

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
23327, 291553

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q96PU5

Gene Symbols:
NEDD4L

Immunogen:
A synthesized peptide derived from human NEDD4L(Accession Q96PU5), corresponding to amino acid residues around phosphorylated Ser479.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA5105697

--


Antigen:
Phospho-LATS2 (Ser380)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
LATS2

Gene Alias:
4932411G09Rik, AV277261, AW228608, h-warts, Kinase phosphorylated during mitosis protein, KPM, large tumor suppressor 2, large tumor suppressor homolog 2, large tumor suppressor kinase 2, large tumor suppressor, homolog 2, LATS (large tumor suppressor, Drosophila) homolog 2, LATS, large tumor suppressor, homolog 2, LATS2, serine/threonine kinase KPM, serine/threonine-protein kinase kpm, Serine/threonine-protein kinase LATS2, si:ch211-173o4.2, Warts-like kinase

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
26524, 50523

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q7TSJ6, Q9NRM7

Gene Symbols:
LATS2

Immunogen:
A synthesized peptide derived from human LATS2(Accession Q9NRM7), corresponding to amino acid residues around phosphorylated Ser380.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

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PIPA5105699

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Antigen:
Phospho-PERK (Ser555)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
EIF2AK3

Gene Alias:
2.7.11.1; AI427929; EIF2AK3; eukaryotic translation initiation factor 2 alpha kinase 3; eukaryotic translation initiation factor 2-alpha kinase 3; HsPEK; OTTHUMP00000207187; OTTHUMP00000207188; Pancreatic eIF2-alpha kinase; PEK; Perk; PRKR-like endoplasmic reticulum kinase; WRS

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
9451

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q9NZJ5

Gene Symbols:
EIF2AK3

Immunogen:
A synthesized peptide derived from human EIF2AK3(Accession Q9NZJ5), corresponding to amino acid residues around phosphorylated Ser555.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA5105702

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Antigen:
Phospho-TACC3 (Tyr560)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TACC3

Gene Alias:
Aint; Arnt interacting protein; ARNT-interacting protein; C86661; ERIC1; ERIC-1; Tacc3; transforming acidic coiled coil 3; transforming acidic coiled-coil containing protein 3; transforming acidic coiled-coil-containing protein 3; transforming, acidic coiled-coil containing protein 3

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10460, 21335, 360962

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q9JJ11, Q9Y6A5

Gene Symbols:
TACC3

Immunogen:
A synthesized peptide derived from human TACC3(Accession Q9Y6A5), corresponding to amino acid residues around phosphorylated Tyr560.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG