PIPA5105806

Phospho-HSF1 (Ser307) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5105806-Each-of-1 In Stock ₹ 43,592.82

PIPA5105806 - Each of 1

₹ 43,592.82

In Stock

Quantity

1

Base Price: ₹ 43,592.82

GST (18%): ₹ 7,846.708

Total Price: ₹ 51,439.528

Antigen

Phospho-HSF1 (Ser307)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Hsf1

Gene Alias

AA960185; heat shock factor 1; heat shock factor 2; Heat shock factor protein 1; Heat shock transcription factor 1; heat shock transcription factor 1 alpha isoform; heat shock transcription factor 1 beta isoform; heat shock transcription factor 1 gammaalpha isoform; heat shock transcription factor 1 gammabeta isoform; HSF; HSF 1; Hsf1; Hsf1alpha; Hsf1beta; Hsf1gammaalpha; Hsf1gammabeta; HSTF 1; HSTF1

Host Species

Rabbit

Purification Method

sequential chromatography

Regulatory Status

RUO

Gene ID (Entrez)

15499, 3297, 79245

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

P38532, Q00613

Gene Symbols

Hsf1

Immunogen

A synthesized peptide derived from human HSF1(Accession Q00613), corresponding to amino acid residues around phosphorylated Ser307.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Related Products

Img

Thermo Scientific

PIPA5105521

--

Img

Thermo Scientific

PIPA5106234

--

Img

Thermo Scientific

PIPA5106084

--

Img

Thermo Scientific

PIPA5105861

--

Img

Thermo Scientific

PIPA5105826

--

Img

Thermo Scientific

PIPA5105490

--

Img

Thermo Scientific

PIPA5106788

--

Img

Thermo Scientific

PIPA5105942

--

Description

  • Antibody detects endogenous levels of HSF1 only when phosphorylated at Ser307
  • All organisms respond to elevated temperatures and a variety of environmental stresses by rapid synthesis of heat shock RNAs and proteins
  • The regulation of heat shock gene transcription is mediated by the transcriptional activator, heat shock factor (HSF), which binds to heat shock response elements (HSEs)
  • These HSEs are found as three repeats of a 5-nucleotide {nGAAn} module, arranged in alternating orientation and present upstream of all heat shock genes
  • The HSEs are highly conserved among species yet HSF purified from yeast, Drosophila and human have different molecular weights and the proteins do not show significant immunological cross reaction
  • Two HSFs have been identified in human cells, HSF1 and HSF2, which bind to the same HSEs and have 38% sequence identity
  • These factors are activated by distinct stimuli, HSF1 is responsive to classical stress signals such as heat, heavy metals and oxidative reagents, whereas HSF2 is activated during hemin-mediated differentiation of human erythroleukemia cells
  • HSF1 exists constitutively in the cytoplasm and the nucleus of unstressed cells as a monomer which lacks DNA binding activity
  • Through an unknown signal generated during stress, HSF1 becomes activated to a nuclear localized, trimeric state which binds to DNA
  • The phosphorylation of HSF1 is necessary for maximal transcription of heat shock genes.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA5105806

--


Antigen:
Phospho-HSF1 (Ser307)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Hsf1

Gene Alias:
AA960185; heat shock factor 1; heat shock factor 2; Heat shock factor protein 1; Heat shock transcription factor 1; heat shock transcription factor 1 alpha isoform; heat shock transcription factor 1 beta isoform; heat shock transcription factor 1 gammaalpha isoform; heat shock transcription factor 1 gammabeta isoform; HSF; HSF 1; Hsf1; Hsf1alpha; Hsf1beta; Hsf1gammaalpha; Hsf1gammabeta; HSTF 1; HSTF1

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
15499, 3297, 79245

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P38532, Q00613

Gene Symbols:
Hsf1

Immunogen:
A synthesized peptide derived from human HSF1(Accession Q00613), corresponding to amino acid residues around phosphorylated Ser307.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5105808

--


Antigen:
Phospho-IL1R1 (Tyr496)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Il1r1

Gene Alias:
antigen CD121a; CD121 alpha; CD121 antigen-like family member A; CD121a; CD121b; D2S1473; il1 receptor; il-1 receptor; IL-1 receptor alpha chain; IL1R; il-1r; IL1R1; IL-1R1; IL-1R-1; Il1r-1; IL1RA; IL-1R-alpha; IL1RT1; IL-1RT1; IL-1RT-1; IL-iR; interleukin 1 beta receptor type 1 short transmembrane form; interleukin 1 beta receptor type 1 soluble form; interleukin 1 bete receptor type 1 long transmembrane form; interleukin 1 receptor alpha, type I; interleukin 1 receptor type 1; interleukin 1 receptor, type I; interleukin-1 receptor; interleukin-1 receptor alpha; Interleukin-1 receptor type 1; Interleukin-1 receptor type 1, membrane form; Interleukin-1 receptor type 1, soluble form; Interleukin-1 receptor type I; mIL-1R1; p80; sIL-1R1

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16177, 25663, 3554

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P13504, P14778, Q02955

Gene Symbols:
Il1r1

Immunogen:
A synthesized peptide derived from human IL1R1(Accession P14778), corresponding to amino acid residues around phosphorylated Tyr496.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5105809

--


Antigen:
Phospho-ITGA4 (Ser1027)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ITGA4

Gene Alias:
269C wild type; alpha 4 subunit of VLA-4 receptor; antigen CD49D, alpha-4 subunit of VLA-4 receptor; CD49 antigen-like family member D; CD49d; IA4; integrin alpha 4; integrin alpha-4; integrin alpha4B; Integrin alpha-IV; integrin subunit alpha 4; integrin, alpha 4; integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor); Itga4; Itga4B; ITGA-IV; LPAM subunit alpha; lymphocyte Peyer patch adhesion molecules subunit alpha; very late activation protein 4 receptor, alpha 4 subunit; VLA-4 receptor, alpha 4 subunit; VLA-4 subunit alpha

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16401, 311144, 3676

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P13612, Q00651

Gene Symbols:
ITGA4

Immunogen:
A synthesized peptide derived from human ITGA4(Accession P13612), corresponding to amino acid residues around phosphorylated Ser1027.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5105812

--


Antigen:
Phospho-KV4.2 (KCND2) (Ser616)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
KCND2

Gene Alias:
AI839615; AW555701; KCND2; KIAA1044; KV4.2; mKIAA1044; MNCb-7013; potassium channel alpha subunit Kv4.2; potassium channel Kv4.2; potassium channel, voltage gated Shal related subfamily D, member 2; potassium channel, voltage-gated Shal-related subfamily D, member 2; potassium voltage gated channel, Shal-related family, member 2; potassium voltage-gated channel subfamily D member 2; potassium voltage-gated channel, Shal-related family, member 2; potassium voltage-gated channel, Shal-related subfamily, member 2; R75121; RK5; Shal1; voltage-gated potassium channel; voltage-gated potassium channel subunit Kv4.2; voltage-sensitive potassium channel

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16508, 3751, 65180

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q63881, Q9NZV8, Q9Z0V2

Gene Symbols:
KCND2

Immunogen:
A synthesized peptide derived from human KCND2(Accession Q9NZV8), corresponding to amino acid residues around phosphorylated Ser616.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG