PIPA5105861
Phospho-STAT4 (Ser721) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5105861-Each-of-1 | In Stock | ₹ 44,191.74 |
PIPA5105861 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,191.74
GST (18%): ₹ 7,954.513
Total Price: ₹ 52,146.253
Antigen
Phospho-STAT4 (Ser721)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
STAT4
Gene Alias
CIS4; HSPC060; OTTHUMP00000163553; Signal transducer and activator of transcription 4; SLEB11; SOCS4; SOCS6; SSI4; STAI4; STAT; Stat4; STATI4
Host Species
Rabbit
Purification Method
sequential chromatography
Regulatory Status
RUO
Gene ID (Entrez)
20849, 367264, 6775
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
P42228, Q14765
Gene Symbols
STAT4
Immunogen
A synthesized peptide derived from human STAT4(Accession Q14765), corresponding to amino acid residues around phosphorylated Ser721.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of STAT4 only when phosphorylated at Ser721
- STAT4 was originally identified using degenerate primers complementary to sequences encoding conserved regions of other STAT proteins
- The STAT4 protein is most similar to STAT1 (52%) and STAT3 (47%)
- Functionally, STAT4 is similar to other STAT family members in that it can be tyrosine phosphorylated by Jak1 or Jak2
- STAT4 forms homodimers and heterodimers with related STAT family members
- Tyrosine phosphorylated STAT4 can bind the IFN-gamma activated site (GAS)
- Serine phosphorylation of STAT is also required for maximal transcriptional activity
- STAT4 expression is restricted to the thymus, spleen and testis
- Until recently the cytokine(s) responsible for activation of STAT4 had not been identified
- STAT4 is now known to be activated by the cytokine interleukin 12 (IL-12)
- IL-12 is required for the T-cell independent induction of IFN-gamma which is a key step in the initial suppression of bacterial and parasitic infections
- In addition, IL-12 is required for the development of a Th1 response which is necessary for effective host defense against intracellular pathogens
- STAT4-deficient mice display impaired IL-12 development of Th1 cells and enhanced development of Th2 cells
- A recent study in mouse has shown that in response to viral infection IFN-a/b activation of STAT4 is required for IFN-g production.
Compare Similar Items
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Antigen: Phospho-STAT4 (Ser721)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: STAT4
Gene Alias: CIS4; HSPC060; OTTHUMP00000163553; Signal transducer and activator of transcription 4; SLEB11; SOCS4; SOCS6; SSI4; STAI4; STAT; Stat4; STATI4
Host Species: Rabbit
Purification Method: sequential chromatography
Regulatory Status: RUO
Gene ID (Entrez): 20849, 367264, 6775
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: P42228, Q14765
Gene Symbols: STAT4
Immunogen: A synthesized peptide derived from human STAT4(Accession Q14765), corresponding to amino acid residues around phosphorylated Ser721.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-STAT4 (Ser721)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
STAT4
Gene Alias:
CIS4; HSPC060; OTTHUMP00000163553; Signal transducer and activator of transcription 4; SLEB11; SOCS4; SOCS6; SSI4; STAI4; STAT; Stat4; STATI4
Host Species:
Rabbit
Purification Method:
sequential chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
20849, 367264, 6775
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
P42228, Q14765
Gene Symbols:
STAT4
Immunogen:
A synthesized peptide derived from human STAT4(Accession Q14765), corresponding to amino acid residues around phosphorylated Ser721.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-VEGF Receptor 1 (Tyr1242)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: FLT1
Gene Alias: AI323757, embryonic receptor kinase 2, Emrk2, FLT, FLT1, FLT-1, fms related tyrosine kinase 1, FMS-like tyrosine kinase 1, FMS-related tyrosine kinase 1, Fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor), FRT, i21, sFlt1, soluble VEGFR 1, sVEGFR 1, Tyrosine-protein kinase FRT, tyrosine-protein kinase receptor FLT, Vascular endothelial growth factor receptor 1, vascular endothelial growth factor receptor-1, vascular permeability factor receptor, VEGF R1, VEGFR1, VEGFR-1
Host Species: Rabbit
Purification Method: sequential chromatography
Regulatory Status: RUO
Gene ID (Entrez): 2321
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: P17948
Gene Symbols: FLT1
Immunogen: A synthesized peptide derived from human FLT1(Accession P17948), corresponding to amino acid residues around phosphorylated Tyr1242.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Non-human Primate
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-VEGF Receptor 1 (Tyr1242)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
FLT1
Gene Alias:
AI323757, embryonic receptor kinase 2, Emrk2, FLT, FLT1, FLT-1, fms related tyrosine kinase 1, FMS-like tyrosine kinase 1, FMS-related tyrosine kinase 1, Fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor), FRT, i21, sFlt1, soluble VEGFR 1, sVEGFR 1, Tyrosine-protein kinase FRT, tyrosine-protein kinase receptor FLT, Vascular endothelial growth factor receptor 1, vascular endothelial growth factor receptor-1, vascular permeability factor receptor, VEGF R1, VEGFR1, VEGFR-1
Host Species:
Rabbit
Purification Method:
sequential chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
2321
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
P17948
Gene Symbols:
FLT1
Immunogen:
A synthesized peptide derived from human FLT1(Accession P17948), corresponding to amino acid residues around phosphorylated Tyr1242.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Non-human Primate
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-ABL1/ABL2 (Tyr70, Tyr116)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ABL2
Gene Alias: AA536808; Abelson murine leukemia oncogene; Abelson murine leukemia viral (v-abl) oncogene homolog 1; Abelson murine leukemia viral (v-abl) oncogene homolog 2; abelson murine leukemia viral oncogene homolog 1; Abelson murine leukemia viral oncogene homolog 2; Abelson tyrosine-protein kinase 1; Abelson tyrosine-protein kinase 2; Abelson-related gene protein; Abl; ABL proto-oncogene 1, non-receptor tyrosine kinase; ABL proto-oncogene 2, non-receptor tyrosine kinase; ABL1; Abl1-related gene product; abl2; ABLL; AI325092; Arg; arg tyrosine kinase; bcr/abl; bcr/c-abl oncogene protein; c-Abl; c-abl oncogene 1, non-receptor tyrosine kinase; c-abl oncogene 1, receptor tyrosine kinase; c-abl oncogene 2, non-receptor tyrosine kinase; c-ABL1; E430008G22Rik; JTK7; p150; Proto-oncogene c-Abl; proto-oncogene tyrosine-protein kinase ABL1; tyrosine kinase ARG; tyrosine-protein kinase ABL1; Tyrosine-protein kinase ABL2; tyrosine-protein kinase ARG; v-abl; v-abl Abelson murine leukemia oncogene 1; v-abl Abelson murine leukemia viral oncogene 1; v-abl Abelson murine leukemia viral oncogene 2; v-abl Abelson murine leukemia viral oncogene 2 (arg, Abelson-related gene); v-abl Abelson murine leukemia viral oncogene homolog 1; v-abl Abelson murine leukemia viral oncogene homolog 2; v-abl Abelson murine leukemia viral oncogene homolog 2 (arg, Abelson-related gene)
Host Species: Rabbit
Purification Method: sequential chromatography
Regulatory Status: RUO
Gene ID (Entrez): 11350, 11352, 25, 27, 304883, 311860
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: P00519, P00520, P42684, Q4JIM5
Gene Symbols: ABL1, ABL2
Immunogen: A synthesized peptide derived from human ABL1(Accession P00519), corresponding to amino acid residues around phosphorylated Tyr70.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Non-human Primate, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-ABL1/ABL2 (Tyr70, Tyr116)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ABL2
Gene Alias:
AA536808; Abelson murine leukemia oncogene; Abelson murine leukemia viral (v-abl) oncogene homolog 1; Abelson murine leukemia viral (v-abl) oncogene homolog 2; abelson murine leukemia viral oncogene homolog 1; Abelson murine leukemia viral oncogene homolog 2; Abelson tyrosine-protein kinase 1; Abelson tyrosine-protein kinase 2; Abelson-related gene protein; Abl; ABL proto-oncogene 1, non-receptor tyrosine kinase; ABL proto-oncogene 2, non-receptor tyrosine kinase; ABL1; Abl1-related gene product; abl2; ABLL; AI325092; Arg; arg tyrosine kinase; bcr/abl; bcr/c-abl oncogene protein; c-Abl; c-abl oncogene 1, non-receptor tyrosine kinase; c-abl oncogene 1, receptor tyrosine kinase; c-abl oncogene 2, non-receptor tyrosine kinase; c-ABL1; E430008G22Rik; JTK7; p150; Proto-oncogene c-Abl; proto-oncogene tyrosine-protein kinase ABL1; tyrosine kinase ARG; tyrosine-protein kinase ABL1; Tyrosine-protein kinase ABL2; tyrosine-protein kinase ARG; v-abl; v-abl Abelson murine leukemia oncogene 1; v-abl Abelson murine leukemia viral oncogene 1; v-abl Abelson murine leukemia viral oncogene 2; v-abl Abelson murine leukemia viral oncogene 2 (arg, Abelson-related gene); v-abl Abelson murine leukemia viral oncogene homolog 1; v-abl Abelson murine leukemia viral oncogene homolog 2; v-abl Abelson murine leukemia viral oncogene homolog 2 (arg, Abelson-related gene)
Host Species:
Rabbit
Purification Method:
sequential chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
11350, 11352, 25, 27, 304883, 311860
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
P00519, P00520, P42684, Q4JIM5
Gene Symbols:
ABL1, ABL2
Immunogen:
A synthesized peptide derived from human ABL1(Accession P00519), corresponding to amino acid residues around phosphorylated Tyr70.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Non-human Primate, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-BLK (Tyr389)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: BLK
Gene Alias: B lymphocyte kinase; B lymphoid kinase; B lymphoid tyrosine kinase; Blk; BLK nonreceptor tyrosine kinase; BLK proto-oncogene, Src family tyrosine kinase; MGC10442; MODY11; p55-Blk; tyrosine-protein kinase Blk
Host Species: Rabbit
Purification Method: sequential chromatography
Regulatory Status: RUO
Gene ID (Entrez): 12143, 364403, 640
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: P16277, P51451
Gene Symbols: BLK
Immunogen: A synthesized peptide derived from human BLK(Accession P51451), corresponding to amino acid residues around phosphorylated Tyr389.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Non-human Primate, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-BLK (Tyr389)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
BLK
Gene Alias:
B lymphocyte kinase; B lymphoid kinase; B lymphoid tyrosine kinase; Blk; BLK nonreceptor tyrosine kinase; BLK proto-oncogene, Src family tyrosine kinase; MGC10442; MODY11; p55-Blk; tyrosine-protein kinase Blk
Host Species:
Rabbit
Purification Method:
sequential chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
12143, 364403, 640
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
P16277, P51451
Gene Symbols:
BLK
Immunogen:
A synthesized peptide derived from human BLK(Accession P51451), corresponding to amino acid residues around phosphorylated Tyr389.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Non-human Primate, Rat
Product Type:
Antibody
Isotype:
IgG