PIPA5105864

Phospho-ABL1/ABL2 (Tyr70, Tyr116) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA5105864-Each-of-1 In Stock ₹ 39,999.30

PIPA5105864 - Each of 1

₹ 39,999.30

In Stock

Quantity

1

Base Price: ₹ 39,999.30

GST (18%): ₹ 7,199.874

Total Price: ₹ 47,199.174

Antigen

Phospho-ABL1/ABL2 (Tyr70, Tyr116)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ABL2

Gene Alias

AA536808; Abelson murine leukemia oncogene; Abelson murine leukemia viral (v-abl) oncogene homolog 1; Abelson murine leukemia viral (v-abl) oncogene homolog 2; abelson murine leukemia viral oncogene homolog 1; Abelson murine leukemia viral oncogene homolog 2; Abelson tyrosine-protein kinase 1; Abelson tyrosine-protein kinase 2; Abelson-related gene protein; Abl; ABL proto-oncogene 1, non-receptor tyrosine kinase; ABL proto-oncogene 2, non-receptor tyrosine kinase; ABL1; Abl1-related gene product; abl2; ABLL; AI325092; Arg; arg tyrosine kinase; bcr/abl; bcr/c-abl oncogene protein; c-Abl; c-abl oncogene 1, non-receptor tyrosine kinase; c-abl oncogene 1, receptor tyrosine kinase; c-abl oncogene 2, non-receptor tyrosine kinase; c-ABL1; E430008G22Rik; JTK7; p150; Proto-oncogene c-Abl; proto-oncogene tyrosine-protein kinase ABL1; tyrosine kinase ARG; tyrosine-protein kinase ABL1; Tyrosine-protein kinase ABL2; tyrosine-protein kinase ARG; v-abl; v-abl Abelson murine leukemia oncogene 1; v-abl Abelson murine leukemia viral oncogene 1; v-abl Abelson murine leukemia viral oncogene 2; v-abl Abelson murine leukemia viral oncogene 2 (arg, Abelson-related gene); v-abl Abelson murine leukemia viral oncogene homolog 1; v-abl Abelson murine leukemia viral oncogene homolog 2; v-abl Abelson murine leukemia viral oncogene homolog 2 (arg, Abelson-related gene)

Host Species

Rabbit

Purification Method

sequential chromatography

Regulatory Status

RUO

Gene ID (Entrez)

11350, 11352, 25, 27, 304883, 311860

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

P00519, P00520, P42684, Q4JIM5

Gene Symbols

ABL1, ABL2

Immunogen

A synthesized peptide derived from human ABL1(Accession P00519), corresponding to amino acid residues around phosphorylated Tyr70.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Non-human Primate, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detectsAntibody detects endogenous levels of ABL1 when phosphorylated at Tyr70 or ABL2 when phosphorylated at Tyr116
  • The Abl oncogene was initially identified as the viral transforming gene of Abelson murine leukemia virus (A-MuLV)
  • The major translational product of c-Abl has been identified as a protein with tyrosine kinase activity and an SH2 domain
  • The Abl oncogene is implicated in several human leukemias including 90-95% of chronic myelocytic leukemia (CML), 20-25% of adult acute lymphoblastic leukemia (ALL) and 2-5% of pediatric ALL
  • In these leukemias the c-Abl proto-oncogene undergoes a (9;22) chromosomal translocation producing the Philadelphia (Ph1) chromosome
  • The molecular consequence of this translocation is the generation of a chimeric Bcr/c-Abl mRNA encoding activated Abl protein-tyrosine kinase.

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PIPA5105864

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Antigen:
Phospho-ABL1/ABL2 (Tyr70, Tyr116)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ABL2

Gene Alias:
AA536808; Abelson murine leukemia oncogene; Abelson murine leukemia viral (v-abl) oncogene homolog 1; Abelson murine leukemia viral (v-abl) oncogene homolog 2; abelson murine leukemia viral oncogene homolog 1; Abelson murine leukemia viral oncogene homolog 2; Abelson tyrosine-protein kinase 1; Abelson tyrosine-protein kinase 2; Abelson-related gene protein; Abl; ABL proto-oncogene 1, non-receptor tyrosine kinase; ABL proto-oncogene 2, non-receptor tyrosine kinase; ABL1; Abl1-related gene product; abl2; ABLL; AI325092; Arg; arg tyrosine kinase; bcr/abl; bcr/c-abl oncogene protein; c-Abl; c-abl oncogene 1, non-receptor tyrosine kinase; c-abl oncogene 1, receptor tyrosine kinase; c-abl oncogene 2, non-receptor tyrosine kinase; c-ABL1; E430008G22Rik; JTK7; p150; Proto-oncogene c-Abl; proto-oncogene tyrosine-protein kinase ABL1; tyrosine kinase ARG; tyrosine-protein kinase ABL1; Tyrosine-protein kinase ABL2; tyrosine-protein kinase ARG; v-abl; v-abl Abelson murine leukemia oncogene 1; v-abl Abelson murine leukemia viral oncogene 1; v-abl Abelson murine leukemia viral oncogene 2; v-abl Abelson murine leukemia viral oncogene 2 (arg, Abelson-related gene); v-abl Abelson murine leukemia viral oncogene homolog 1; v-abl Abelson murine leukemia viral oncogene homolog 2; v-abl Abelson murine leukemia viral oncogene homolog 2 (arg, Abelson-related gene)

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11350, 11352, 25, 27, 304883, 311860

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P00519, P00520, P42684, Q4JIM5

Gene Symbols:
ABL1, ABL2

Immunogen:
A synthesized peptide derived from human ABL1(Accession P00519), corresponding to amino acid residues around phosphorylated Tyr70.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA5105866

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Antigen:
Phospho-BLK (Tyr389)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
BLK

Gene Alias:
B lymphocyte kinase; B lymphoid kinase; B lymphoid tyrosine kinase; Blk; BLK nonreceptor tyrosine kinase; BLK proto-oncogene, Src family tyrosine kinase; MGC10442; MODY11; p55-Blk; tyrosine-protein kinase Blk

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12143, 364403, 640

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P16277, P51451

Gene Symbols:
BLK

Immunogen:
A synthesized peptide derived from human BLK(Accession P51451), corresponding to amino acid residues around phosphorylated Tyr389.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA5105867

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Antigen:
Phospho-BRK (Tyr342)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PTK6

Gene Alias:
ALT-PTK6; breast tumor kinase; BRK; deltam5; FLJ42088; protein tyrosine kinase 6; protein-tyrosine kinase 6; protein-tyrosine kinase BRK; Ptk6; PTK6 protein tyrosine kinase 6; Sik; SRC-related intestinal kinase; tks; Tksk; tyrosine kinase identified from skin; tyrosine-protein kinase BRK

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20459, 366275, 5753

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q13882, Q64434

Gene Symbols:
PTK6

Immunogen:
A synthesized peptide derived from human PTK6(Accession Q13882), corresponding to amino acid residues around phosphorylated Tyr342.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA5105868

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Antigen:
Phospho-BRSK2 (Thr260)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Brsk2

Gene Alias:
4833424K13Rik; BR serine/threonine kinase 2; BR serine/threonine-protein kinase 2; brain serine/threonine kinase 2; brain-selective kinase 2; Brain-specific serine/threonine-protein kinase 2; BRSK2; C11orf7; HUSSY-12; Kiaa4256; PEN11B; protein kinase SAD1B; SAD1; SAD1B; Sada; SAD-A; serine/threonine-protein kinase 29; Serine/threonine-protein kinase BRSK2; serine/threonine-protein kinase SAD-A; STK29; testicular tissue protein Li 30

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
75770, 9024

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q69Z98, Q8IWQ3

Gene Symbols:
Brsk2

Immunogen:
A synthesized peptide derived from human BRSK2(Accession Q8IWQ3), corresponding to amino acid residues around phosphorylated Thr260.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG