PIPA5105868

Phospho-BRSK2 (Thr260) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5105868-Each-of-1 In Stock ₹ 44,705.10

PIPA5105868 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

Phospho-BRSK2 (Thr260)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Brsk2

Gene Alias

4833424K13Rik; BR serine/threonine kinase 2; BR serine/threonine-protein kinase 2; brain serine/threonine kinase 2; brain-selective kinase 2; Brain-specific serine/threonine-protein kinase 2; BRSK2; C11orf7; HUSSY-12; Kiaa4256; PEN11B; protein kinase SAD1B; SAD1; SAD1B; Sada; SAD-A; serine/threonine-protein kinase 29; Serine/threonine-protein kinase BRSK2; serine/threonine-protein kinase SAD-A; STK29; testicular tissue protein Li 30

Host Species

Rabbit

Purification Method

sequential chromatography

Regulatory Status

RUO

Gene ID (Entrez)

75770, 9024

Content And Storage

-20°C

Form

Liquid

Applications

Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

Q69Z98, Q8IWQ3

Gene Symbols

Brsk2

Immunogen

A synthesized peptide derived from human BRSK2(Accession Q8IWQ3), corresponding to amino acid residues around phosphorylated Thr260.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

Related Products

Img

Thermo Scientific

PIPA5105631

--

Img

Thermo Scientific

PIPA5105918

--

Img

Thermo Scientific

PIPA5105665

--

Img

Thermo Scientific

PIPA5105905

--

Img

Thermo Scientific

PIPA5105896

--

Img

Thermo Scientific

PIPA5105901

--

Img

Thermo Scientific

PIPA5106513

--

Img

Thermo Scientific

PIPA5105640

--

Description

  • Antibody detects endogenous levels of BRSK2 only when phosphorylated at Thr260
  • BRSK2 is a brain-selective serine/threonine kinase 2 that is mainly expressed in the brain, with weaker expression in testis and pancreas
  • BRSK2 expressed in insect cells specifically phosphorylates WEE1A, CDC25C and CDC25B in an in vitro assay
  • DNA damage induced by μgtraviolet (UV) irradiation or methyl methane sulfonate, but not by ionizing radiation, enhanced endogenous BRSK2 kinase activity in a caffeine-sensitive manner and caused translocation of BRSK2 from the cytoplasm to the nucleus
  • Overexpression of BRSK2 in HeLa cells results in increased phosphorylation of CDC25C
  • DNA damage induced by μgtraviolet (UV) irradiation or methyl methane sulfonate, but not by ionizing radiation, enhances endogenous BRSK2 kinase activity in a caffeine-sensitive manner and causes translocation of BRSK2 from the cytoplasm to the nucleus
  • Overexpression of BRSK2 induces G2/M arrest in HeLa cells
  • Small interfering RNA against BRSK2 partly abrogates UV-induced G2/M arrest
  • BRSK2 may act as a checkpoint kinase upon DNA damage induced by UV irradiation or methyl methane sulfonate.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA5105868

--


Antigen:
Phospho-BRSK2 (Thr260)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Brsk2

Gene Alias:
4833424K13Rik; BR serine/threonine kinase 2; BR serine/threonine-protein kinase 2; brain serine/threonine kinase 2; brain-selective kinase 2; Brain-specific serine/threonine-protein kinase 2; BRSK2; C11orf7; HUSSY-12; Kiaa4256; PEN11B; protein kinase SAD1B; SAD1; SAD1B; Sada; SAD-A; serine/threonine-protein kinase 29; Serine/threonine-protein kinase BRSK2; serine/threonine-protein kinase SAD-A; STK29; testicular tissue protein Li 30

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
75770, 9024

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q69Z98, Q8IWQ3

Gene Symbols:
Brsk2

Immunogen:
A synthesized peptide derived from human BRSK2(Accession Q8IWQ3), corresponding to amino acid residues around phosphorylated Thr260.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5105871

--


Antigen:
Phospho-CSK (Tyr304)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CSK

Gene Alias:
AW212630; CSK; CSK, non-receptor tyrosine kinase; C-SRC kinase; c-src tyrosine kinase; C-terminal Src kinase; MGC117393; p50CSK; protein-tyrosine kinase (CSK); protein-tyrosine kinase CYL; Protein-tyrosine kinase MPK-2; Tyrosine-protein kinase CSK

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12988, 1445, 315707

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P32577, P41240, P41241

Gene Symbols:
CSK

Immunogen:
A synthesized peptide derived from human CSK(Accession P41240), corresponding to amino acid residues around phosphorylated Tyr304.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5105872

--


Antigen:
Phospho-DAPK1 (Ser734)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DAPK1

Gene Alias:
D13Ucla1; DAP kinase 1; DAPK; DAPK1; DAP-Kinase; death associated protein kinase 1; death-associated protein kinase 1; DKFZp781I035; OTTHUMP00000216193

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1612, 306722, 69635

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P53355, Q80YE7

Gene Symbols:
DAPK1

Immunogen:
A synthesized peptide derived from human DAPK1(Accession P53355), corresponding to amino acid residues around phosphorylated Ser734.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5105874

--


Antigen:
Phospho-DYRK1A/DYRK1B (Tyr321, Tyr273)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DYRK1A

Gene Alias:
2310043O08Rik; AOMS3; D16Ertd272e; D16Ertd493e; dual specificity tyrosine phosphorylation regulated kinase 1A; dual specificity tyrosine phosphorylation regulated kinase 1B; dual specificity tyrosine-(Y)-phosphorylation regulated kinase 1A; dual specificity tyrosine-(Y)-phosphorylation regulated kinase 1B; dual specificity tyrosine-phosphorylation-regulated kinase 1A; Dual specificity tyrosine-phosphorylation-regulated kinase 1B; Dual Specificity Yak1-related kinase; dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A; dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b; Dyrk; DYRK1; Dyrk1a; Dyrk1b; ENSMUSG00000074897; Gm10783; hMNB; HP86; Minibrain-related kinase; MIRK; Mirk protein kinase; mmb; MNB; mnb protein kinase homolog hp86; MNB/DYRK protein kinase; MNBH; MP86; MRD7; protein kinase minibrain homolog; PSK47; RP86; serine/threonine kinase MNB; serine/threonine-specific protein kinase

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
13548, 13549, 1859, 25255, 308468, 9149

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q13627, Q61214, Q63470, Q9Y463, Q9Z188

Gene Symbols:
DYRK1A, DYRK1B

Immunogen:
A synthesized peptide derived from human DYRK1A(Accession Q13627), corresponding to amino acid residues around phosphorylated Tyr321.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG