PIPA5105863

Phospho-VEGF Receptor 1 (Tyr1242) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5105863-Each-of-1 In Stock ₹ 39,913.74

PIPA5105863 - Each of 1

₹ 39,913.74

In Stock

Quantity

1

Base Price: ₹ 39,913.74

GST (18%): ₹ 7,184.473

Total Price: ₹ 47,098.213

Antigen

Phospho-VEGF Receptor 1 (Tyr1242)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

FLT1

Gene Alias

AI323757, embryonic receptor kinase 2, Emrk2, FLT, FLT1, FLT-1, fms related tyrosine kinase 1, FMS-like tyrosine kinase 1, FMS-related tyrosine kinase 1, Fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor), FRT, i21, sFlt1, soluble VEGFR 1, sVEGFR 1, Tyrosine-protein kinase FRT, tyrosine-protein kinase receptor FLT, Vascular endothelial growth factor receptor 1, vascular endothelial growth factor receptor-1, vascular permeability factor receptor, VEGF R1, VEGFR1, VEGFR-1

Host Species

Rabbit

Purification Method

sequential chromatography

Regulatory Status

RUO

Gene ID (Entrez)

2321

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

P17948

Gene Symbols

FLT1

Immunogen

A synthesized peptide derived from human FLT1(Accession P17948), corresponding to amino acid residues around phosphorylated Tyr1242.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Non-human Primate

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of VEGFR1 only when phosphorylated at Tyr1242
  • FLT1 (VEGFR1) is a receptor tyrosine kinase which plays a critical role in angiogenesis
  • Active angiogenesis has been found to play important role in many pathological and physiological processes, such as tumor progression, diabetic retinopathy, rheumatoid arthritis and wound healing
  • May play an essential role as a negative regulator of embryonic angiogenesis by inhibiting excessive proliferation of endothelial cells
  • Can promote endothelial cell proliferation, survival and angiogenesis in adulthood
  • Its function in promoting cell proliferation seems to be cell-type specific
  • Promotes PGF-mediated proliferation of endothelial cells, proliferation of some types of cancer cells, but does not promote proliferation of normal fibroblasts (in vitro)
  • Has very high affinity for VEGFA and relatively low protein kinase activity; may function as a negative regulator of VEGFA signaling by limiting the amount of free VEGFA and preventing its binding to KDR.

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Thermo Scientific

PIPA5105863

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Antigen:
Phospho-VEGF Receptor 1 (Tyr1242)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
FLT1

Gene Alias:
AI323757, embryonic receptor kinase 2, Emrk2, FLT, FLT1, FLT-1, fms related tyrosine kinase 1, FMS-like tyrosine kinase 1, FMS-related tyrosine kinase 1, Fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor), FRT, i21, sFlt1, soluble VEGFR 1, sVEGFR 1, Tyrosine-protein kinase FRT, tyrosine-protein kinase receptor FLT, Vascular endothelial growth factor receptor 1, vascular endothelial growth factor receptor-1, vascular permeability factor receptor, VEGF R1, VEGFR1, VEGFR-1

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2321

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P17948

Gene Symbols:
FLT1

Immunogen:
A synthesized peptide derived from human FLT1(Accession P17948), corresponding to amino acid residues around phosphorylated Tyr1242.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Non-human Primate

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5105864

--


Antigen:
Phospho-ABL1/ABL2 (Tyr70, Tyr116)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ABL2

Gene Alias:
AA536808; Abelson murine leukemia oncogene; Abelson murine leukemia viral (v-abl) oncogene homolog 1; Abelson murine leukemia viral (v-abl) oncogene homolog 2; abelson murine leukemia viral oncogene homolog 1; Abelson murine leukemia viral oncogene homolog 2; Abelson tyrosine-protein kinase 1; Abelson tyrosine-protein kinase 2; Abelson-related gene protein; Abl; ABL proto-oncogene 1, non-receptor tyrosine kinase; ABL proto-oncogene 2, non-receptor tyrosine kinase; ABL1; Abl1-related gene product; abl2; ABLL; AI325092; Arg; arg tyrosine kinase; bcr/abl; bcr/c-abl oncogene protein; c-Abl; c-abl oncogene 1, non-receptor tyrosine kinase; c-abl oncogene 1, receptor tyrosine kinase; c-abl oncogene 2, non-receptor tyrosine kinase; c-ABL1; E430008G22Rik; JTK7; p150; Proto-oncogene c-Abl; proto-oncogene tyrosine-protein kinase ABL1; tyrosine kinase ARG; tyrosine-protein kinase ABL1; Tyrosine-protein kinase ABL2; tyrosine-protein kinase ARG; v-abl; v-abl Abelson murine leukemia oncogene 1; v-abl Abelson murine leukemia viral oncogene 1; v-abl Abelson murine leukemia viral oncogene 2; v-abl Abelson murine leukemia viral oncogene 2 (arg, Abelson-related gene); v-abl Abelson murine leukemia viral oncogene homolog 1; v-abl Abelson murine leukemia viral oncogene homolog 2; v-abl Abelson murine leukemia viral oncogene homolog 2 (arg, Abelson-related gene)

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11350, 11352, 25, 27, 304883, 311860

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P00519, P00520, P42684, Q4JIM5

Gene Symbols:
ABL1, ABL2

Immunogen:
A synthesized peptide derived from human ABL1(Accession P00519), corresponding to amino acid residues around phosphorylated Tyr70.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5105866

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Antigen:
Phospho-BLK (Tyr389)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
BLK

Gene Alias:
B lymphocyte kinase; B lymphoid kinase; B lymphoid tyrosine kinase; Blk; BLK nonreceptor tyrosine kinase; BLK proto-oncogene, Src family tyrosine kinase; MGC10442; MODY11; p55-Blk; tyrosine-protein kinase Blk

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12143, 364403, 640

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P16277, P51451

Gene Symbols:
BLK

Immunogen:
A synthesized peptide derived from human BLK(Accession P51451), corresponding to amino acid residues around phosphorylated Tyr389.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA5105867

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Antigen:
Phospho-BRK (Tyr342)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PTK6

Gene Alias:
ALT-PTK6; breast tumor kinase; BRK; deltam5; FLJ42088; protein tyrosine kinase 6; protein-tyrosine kinase 6; protein-tyrosine kinase BRK; Ptk6; PTK6 protein tyrosine kinase 6; Sik; SRC-related intestinal kinase; tks; Tksk; tyrosine kinase identified from skin; tyrosine-protein kinase BRK

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20459, 366275, 5753

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q13882, Q64434

Gene Symbols:
PTK6

Immunogen:
A synthesized peptide derived from human PTK6(Accession Q13882), corresponding to amino acid residues around phosphorylated Tyr342.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG