PIPA5105895
Phospho-LATS1/LATS2 (Ser909, Ser872) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5105895-Each-of-1 | In Stock | ₹ 42,394.98 |
PIPA5105895 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 42,394.98
GST (18%): ₹ 7,631.096
Total Price: ₹ 50,026.076
Antigen
Phospho-LATS1/LATS2 (Ser909, Ser872)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Lats1
Gene Alias
4932411G09Rik; AV277261; AW208599; AW228608; h-warts; kinase phosphorylated during mitosis protein; KPM; large tumor suppressor; large tumor suppressor 2; large tumor suppressor homolog 1; Large tumor suppressor homolog 2; large tumor suppressor kinase 1; large tumor suppressor kinase 2; large tumor suppressor, homolog 2; large tumor supressor, homolog 1; LATS (large tumor suppressor, Drosophila) homolog 1; LATS (large tumor suppressor, Drosophila) homolog 2; LATS, large tumor suppressor, homolog 1; LATS, large tumor suppressor, homolog 2; lats1; Lats2; RGD1564085; serine/threonine kinase KPM; serine/threonine-protein kinase kpm; Serine/threonine-protein kinase LATS1; serine/threonine-protein kinase LATS2; WARTS; WARTS protein kinase; warts-like kinase; wts
Host Species
Rabbit
Purification Method
sequential chromatography
Regulatory Status
RUO
Gene ID (Entrez)
16798, 26524, 305922, 308265, 50523, 9113
Content And Storage
-20°C
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
O95835, Q7TSJ6, Q8BYR2, Q9NRM7
Gene Symbols
Lats1, Lats2
Immunogen
A synthesized peptide derived from human LATS1(Accession O95835), corresponding to amino acid residues around phosphorylated Ser872.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of LATS1/2 only when phosphorylated at Ser909/872
- The protein encoded by this gene is a putative serine/threonine kinase that localizes to the mitotic apparatus and complexes with cell cycle controller CDC2 kinase in early mitosis
- The protein is phosphorylated in a cell-cycle dependent manner, with late prophase phosphorylation remaining through metaphase
- The N-terminal region of the protein binds CDC2 to form a complex showing reduced H1 histone kinase activity, indicating a role as a negative regulator of CDC2/cyclin A
- In addition, the C-terminal kinase domain binds to its own N-terminal region, suggesting potential negative regulation through interference with complex formation via intramolecular binding
- Biochemical and genetic data suggest a role as a tumor suppressor
- This is supported by studies in knockout mice showing development of soft-tissue sarcomas, ovarian stromal cell tumors and a high sensitivity to carcinogenic treatments.
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Antigen: Phospho-LATS1/LATS2 (Ser909, Ser872)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Lats1
Gene Alias: 4932411G09Rik; AV277261; AW208599; AW228608; h-warts; kinase phosphorylated during mitosis protein; KPM; large tumor suppressor; large tumor suppressor 2; large tumor suppressor homolog 1; Large tumor suppressor homolog 2; large tumor suppressor kinase 1; large tumor suppressor kinase 2; large tumor suppressor, homolog 2; large tumor supressor, homolog 1; LATS (large tumor suppressor, Drosophila) homolog 1; LATS (large tumor suppressor, Drosophila) homolog 2; LATS, large tumor suppressor, homolog 1; LATS, large tumor suppressor, homolog 2; lats1; Lats2; RGD1564085; serine/threonine kinase KPM; serine/threonine-protein kinase kpm; Serine/threonine-protein kinase LATS1; serine/threonine-protein kinase LATS2; WARTS; WARTS protein kinase; warts-like kinase; wts
Host Species: Rabbit
Purification Method: sequential chromatography
Regulatory Status: RUO
Gene ID (Entrez): 16798, 26524, 305922, 308265, 50523, 9113
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: O95835, Q7TSJ6, Q8BYR2, Q9NRM7
Gene Symbols: Lats1, Lats2
Immunogen: A synthesized peptide derived from human LATS1(Accession O95835), corresponding to amino acid residues around phosphorylated Ser872.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-LATS1/LATS2 (Ser909, Ser872)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Lats1
Gene Alias:
4932411G09Rik; AV277261; AW208599; AW228608; h-warts; kinase phosphorylated during mitosis protein; KPM; large tumor suppressor; large tumor suppressor 2; large tumor suppressor homolog 1; Large tumor suppressor homolog 2; large tumor suppressor kinase 1; large tumor suppressor kinase 2; large tumor suppressor, homolog 2; large tumor supressor, homolog 1; LATS (large tumor suppressor, Drosophila) homolog 1; LATS (large tumor suppressor, Drosophila) homolog 2; LATS, large tumor suppressor, homolog 1; LATS, large tumor suppressor, homolog 2; lats1; Lats2; RGD1564085; serine/threonine kinase KPM; serine/threonine-protein kinase kpm; Serine/threonine-protein kinase LATS1; serine/threonine-protein kinase LATS2; WARTS; WARTS protein kinase; warts-like kinase; wts
Host Species:
Rabbit
Purification Method:
sequential chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
16798, 26524, 305922, 308265, 50523, 9113
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
O95835, Q7TSJ6, Q8BYR2, Q9NRM7
Gene Symbols:
Lats1, Lats2
Immunogen:
A synthesized peptide derived from human LATS1(Accession O95835), corresponding to amino acid residues around phosphorylated Ser872.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-LKB1 (Ser334)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: STK11
Gene Alias: AA408040; CAMK group; CAMKL family; hLKB1; liver kinase B1; Liver kinase B1 homolog; LKB 1; LKB1; LKB-1; LKB1(S); Par-4; PJS; polarization-related protein LKB1; R75140; renal carcinoma antigen NY-REN-19; serine/threonine kinase 11; serine/threonine-protein kinase 11; serine/threonine-protein kinase LKB1; serine/threonine-protein kinase STK11; STK11
Host Species: Rabbit
Purification Method: sequential chromatography
Regulatory Status: RUO
Gene ID (Entrez): 20869, 314621, 6794
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: D4AE59, Q15831, Q9WTK7
Gene Symbols: STK11
Immunogen: A synthesized peptide derived from human STK11(Accession Q15831), corresponding to amino acid residues around phosphorylated Ser334.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-LKB1 (Ser334)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
STK11
Gene Alias:
AA408040; CAMK group; CAMKL family; hLKB1; liver kinase B1; Liver kinase B1 homolog; LKB 1; LKB1; LKB-1; LKB1(S); Par-4; PJS; polarization-related protein LKB1; R75140; renal carcinoma antigen NY-REN-19; serine/threonine kinase 11; serine/threonine-protein kinase 11; serine/threonine-protein kinase LKB1; serine/threonine-protein kinase STK11; STK11
Host Species:
Rabbit
Purification Method:
sequential chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
20869, 314621, 6794
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
D4AE59, Q15831, Q9WTK7
Gene Symbols:
STK11
Immunogen:
A synthesized peptide derived from human STK11(Accession Q15831), corresponding to amino acid residues around phosphorylated Ser334.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-MEKK2 (Ser520)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Map3k2
Gene Alias: 2.7.11.25; 9630061B06Rik; AI585793; MAP/ERK kinase kinase 2; MAP3K2; MAPK/ERK kinase kinase 2; MAPKKK2; MEK kinase 2; MEKK 2; MEKK2; MEKK2B; mitogen activated protein kinase kinase kinase 2; mitogen-activated protein kinase kinase kinase 2; protein kinase MEKK2b
Host Species: Rabbit
Purification Method: sequential chromatography
Regulatory Status: RUO
Gene ID (Entrez): 10746, 171492, 26405
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: Q61083, Q9Y2U5
Gene Symbols: Map3k2
Immunogen: A synthesized peptide derived from human MAP3K2(Accession Q9Y2U5), corresponding to amino acid residues around phosphorylated Ser520.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-MEKK2 (Ser520)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Map3k2
Gene Alias:
2.7.11.25; 9630061B06Rik; AI585793; MAP/ERK kinase kinase 2; MAP3K2; MAPK/ERK kinase kinase 2; MAPKKK2; MEK kinase 2; MEKK 2; MEKK2; MEKK2B; mitogen activated protein kinase kinase kinase 2; mitogen-activated protein kinase kinase kinase 2; protein kinase MEKK2b
Host Species:
Rabbit
Purification Method:
sequential chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
10746, 171492, 26405
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
Q61083, Q9Y2U5
Gene Symbols:
Map3k2
Immunogen:
A synthesized peptide derived from human MAP3K2(Accession Q9Y2U5), corresponding to amino acid residues around phosphorylated Ser520.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-MEK5 (Thr315)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MAP2K5
Gene Alias: AI324775; AI428457; Dual specificity mitogen-activated protein kinase kinase 5; HsT17454; MAP kinase kinase 5; MAP kinase kinase MEK5b; MAP2K5; MAPK/ERK kinase 5; MAPK/ERK kinese 5; MAPKK 5; Mapkk5; MEK 5; MEK5; mitogen activated protein kinase kinase 5; mitogen-activated protein kinase kinase 5; Mkk5; PRKMK5
Host Species: Rabbit
Purification Method: sequential chromatography
Regulatory Status: RUO
Gene ID (Entrez): 23938, 29568, 5607
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: Q13163, Q62862, Q9WVS7
Gene Symbols: MAP2K5
Immunogen: A synthesized peptide derived from human MAP2K5(Accession Q13163), corresponding to amino acid residues around phosphorylated Thr315.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-MEK5 (Thr315)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MAP2K5
Gene Alias:
AI324775; AI428457; Dual specificity mitogen-activated protein kinase kinase 5; HsT17454; MAP kinase kinase 5; MAP kinase kinase MEK5b; MAP2K5; MAPK/ERK kinase 5; MAPK/ERK kinese 5; MAPKK 5; Mapkk5; MEK 5; MEK5; mitogen activated protein kinase kinase 5; mitogen-activated protein kinase kinase 5; Mkk5; PRKMK5
Host Species:
Rabbit
Purification Method:
sequential chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
23938, 29568, 5607
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
Q13163, Q62862, Q9WVS7
Gene Symbols:
MAP2K5
Immunogen:
A synthesized peptide derived from human MAP2K5(Accession Q13163), corresponding to amino acid residues around phosphorylated Thr315.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG