PIPA5105945

Phospho-CD22 (Tyr842) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA5105945-Each-of-1 In Stock ₹ 44,191.74

PIPA5105945 - Each of 1

₹ 44,191.74

In Stock

Quantity

1

Base Price: ₹ 44,191.74

GST (18%): ₹ 7,954.513

Total Price: ₹ 52,146.253

Antigen

Phospho-CD22 (Tyr842)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

CD22

Gene Alias

A530093D23; B-cell receptor CD22; BL-CAM; B-lymphocyte cell adhesion molecule; B-lymphocyte cell adhesion molecule (BL-CAM); Cd22; CD22 antigen; CD22 molecule; FLJ22814; Lectin 2; Leu-14; Lyb8; Lyb-8; MGC130020; sialic acid binding Ig-like lectin 2; sialic acid-binding Ig-like lectin 2; Sialic acid-binding Ig-like lectin 2 (Siglec-2); Siglec2; Siglec-2; T-cell surface antigen Leu-14

Host Species

Rabbit

Purification Method

sequential chromatography

Regulatory Status

RUO

Gene ID (Entrez)

12483, 308501, 933

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

P20273, P35329

Gene Symbols

CD22

Immunogen

A synthesized peptide derived from human CD22(Accession P20273), corresponding to amino acid residues around phosphorylated Tyr842.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of CD22 only when phosphorylated at Tyr842
  • CD22 (BL-CAM) is a type 1 integral membrane glycoprotein with molecular weight of 130 to 140 kDa
  • CD22 is expressed in both the cytoplasm and cell membrane of B-lymphocytes
  • CD22 antigen appears early in B-cell lymphocyte differentiation at approximately the same stage as the CD19 antigen
  • Unlike other B-cell markers, CD22 membrane expression is limited to the late differentiation stages comprised between mature B cells (CD22+) and plasma cells (CD22-), and may thus prove useful in phenotyping mature leukemias
  • CD22 is also strongly expressed in hairy cell leukemia
  • CD22 preferentially binds to alpha2,6-linked sialic acid
  • The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface
  • Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B cell antigen receptor signaling
  • CD22 plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules
  • CD22 is also strongly expressed in hairy cell leukemia
  • CD22 is also positive in diffuse large B-cell lymphoma and nodular lymphocyte predominance Hodgkin’s lymphoma, but negative in classical Hodgkin’s lymphoma.

Compare Similar Items

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PIPA5105945

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Antigen:
Phospho-CD22 (Tyr842)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CD22

Gene Alias:
A530093D23; B-cell receptor CD22; BL-CAM; B-lymphocyte cell adhesion molecule; B-lymphocyte cell adhesion molecule (BL-CAM); Cd22; CD22 antigen; CD22 molecule; FLJ22814; Lectin 2; Leu-14; Lyb8; Lyb-8; MGC130020; sialic acid binding Ig-like lectin 2; sialic acid-binding Ig-like lectin 2; Sialic acid-binding Ig-like lectin 2 (Siglec-2); Siglec2; Siglec-2; T-cell surface antigen Leu-14

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12483, 308501, 933

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P20273, P35329

Gene Symbols:
CD22

Immunogen:
A synthesized peptide derived from human CD22(Accession P20273), corresponding to amino acid residues around phosphorylated Tyr842.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA5105946

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Antigen:
Phospho-Androgen Receptor (Tyr269)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
AR

Gene Alias:
AIS; Andr; androgen nuclear receptor variant 2; androgen receptor; androgen receptor (Testicular feminization), same as Tfm; androgen receptor splice variant 4b; Ar; AR8; AR-A; AW320017; DHTR; dihydrotestosterone receptor; HUMARA; HYSP1; KD; NR3C4; Nuclear receptor subfamily 3 group C member 4; RP11-383C12.1; SBMA; SMAX1; TFM; Variant AR45

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11835, 24208, 367

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P10275, P15207, P19091

Gene Symbols:
AR

Immunogen:
A synthesized peptide derived from human AR(Accession P10275), corresponding to amino acid residues around phosphorylated Tyr269.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA5105950

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Antigen:
Phospho-EphB1/EphB3/EphB4 (Tyr778, Tyr792, Tyr774)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
EPHB3

Gene Alias:
9330129L11; AI042935; AW456895; AW488255; C130099E04Rik; Cek10; Cek6; Developmental kinase 2; developmental kinase 5; EK2; EK6; Elk; Elkh; ELK-related protein tyrosine kinase; Embryonic kinase 2; ENSMUSG00000074119; EPH receptor B1; Eph receptor B2 (ELK-related protein tyrosine kinase); Eph receptor B3; Eph receptor B4; eph tyrosine kinase 2; Ephb1; Ephb2; EPHB3; Ephb4; EPH-like kinase 2; EPH-like kinase 6; EPH-like tyrosine kinase 2; EPH-like tyrosine kinase-2; ephrin receptor EphB4; ephrin type-B receptor 1; Ephrin type-B receptor 3; ephrin type-B receptor 4; EPHT2; Epth2; Erk; ETK2; HEK2; Hek6; Hepatoma transmembrane kinase; HTK; human embryo kinase 2; MDK2; mDK-2; Mdk5; mDK-5; Myk1; NET; Neuronally-expressed EPH-related tyrosine kinase; Sek4; soluble EPHB1 variant 1; soluble EPHB4 variant 1; soluble EPHB4 variant 2; soluble EPHB4 variant 3; Tyro11; TYRO6; Tyrosine kinase MYK-1; tyrosine-protein kinase receptor EPH-2; tyrosine-protein kinase receptor HTK; tyrosine-protein kinase receptor SEK-4; Tyrosine-protein kinase TYRO11; tyrosine-protein kinase TYRO6

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
13845, 13846, 2047, 2049, 2050, 24338, 270190, 287989, 686310

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P09759, P54753, P54754, P54760, P54761, P54762, Q8CBF3

Gene Symbols:
EPHB1, EPHB3, EPHB4

Immunogen:
A synthesized peptide derived from human EPHB1(Accession P54762), corresponding to amino acid residues around phosphorylated Tyr778.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA5105951

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Antigen:
Phospho-Histone H2A (Ser2)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
H2AC11

Gene Alias:
1190022L06; Acetyl-Histone H2; AW228881; dJ160A22.4; dJ86C11.1; gammaH2ax; H2A; H2A 615 antibody; H2A GL101 antibody; H2A histone; H2A histone family member; H2A histone family member X; H2A histone family member Z; H2A histone family member Z L homeolog; H2A histone family, member A; H2A histone family, member C; H2A histone family, member E; H2A histone family, member G; H2A histone family, member M; H2A histone family, member P; H2A histone family, member Q; H2A histone family, member V; H2A histone family, member X; H2A histone family, member Z; H2A.1; H2A.1 antibody; H2A.1b; H2A.2; H2A.3; H2a.x; H2A.Z; H2A.Z1; H2a.z-1; H2A.Zl; h2a.zl1; h2a.zl2; H2A/a; H2A/c; H2A/d; H2A/E; H2A/g; H2A/m; H2A/p; H2A/q; H2A/S; H2A/X; H2A/z; H2a-291A; H2a-53; h2a-A; H2AC11; H2AC13; H2AC15; H2AC16; H2AC17; h2ad; H2ae; H2AFA; H2AFALii; H2AFC; H2AFD; H2AFE; H2AFG; H2AFI; H2AFM; H2AFN; H2AFP; H2AFQ; H2AFV; H2afx; H2afz; h2afz.L; H2AG; H2A-GL101; H2AH; h2ai; H2A-III; H2ak; H2AK5ac; H2AX; H2AX histone; H2Az;

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
15270, 221613, 24828, 24829, 255626, 3012, 3013, 3014, 3015, 319165, 319166, 319167, 319168, 319172, 319174, 319191, 500987, 51788, 58940, 680322, 8329, 8331, 8335, 85235, 8969

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
C0HKE1, C0HKE3, C0HKE4, C0HKE5, C0HKE6, P04908, P0C0S5, P0C0S6, P0C0S7, P0C0S8, P16104, P20671, P27661, Q00728, Q00729, Q8CGP6, Q96A08, Q96KK5, Q96QV6, Q99878

Gene Symbols:
H2ac1, H2AC11, H2AC12, H2AC13, H2AC14, H2AC4, H2AC7, H2AC8, H2AFX, H2AX, H2AZ1, H2bc1

Immunogen:
A synthesized peptide derived from human Histone H2A(Accession P04908), corresponding to amino acid residues around phosphorylated Ser2.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG