PIPA5105974
Phospho-Bora (Ser497) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5105974-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5105974 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
Phospho-Bora (Ser497)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
BORA
Gene Alias
6720463M24Rik; AI317232; aurora borealis; BORA; bora, aurora kinase A activator; C13orf34; HsBora; Protein aurora borealis; RGD1309522; RP11-342J4.2
Host Species
Rabbit
Purification Method
sequential chromatography
Regulatory Status
RUO
Gene ID (Entrez)
306102, 79866
Content And Storage
-20°C
Form
Liquid
Applications
Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
Q5M864, Q6PGQ7
Gene Symbols
BORA
Immunogen
A synthesized peptide derived from human BORA(Accession Q6PGQ7), corresponding to amino acid residues around phosphorylated Ser497.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of BORA only when phosphorylated at Ser497
- Bora (Protein aurora borealis) is a key activator of Aurora Related Protein Kinase A (ARK-1), which is a centrosome-associated serine/threonine kinase that regulates centrosome maturation, bipolar spindle assembly and chromosome segregation during mitosis
- Bora is localized to the nucleus until mitosis is initiated, then translocates to the cytoplasm in a Cdc2 dependent manner
- Activation of Cdc2 initiates the release of Bora into the cytoplasm where it can bind and activate ARK-1
- PLK1 (polo-like kinase-1) interacts with Bora to control the accessibility of its activation loop for phosphorylation and activation by ARK-1
- Bora and ARK-1 cooperatively activate PLK1 and control mitotic entry
- Bora mutants result in multipolar spindles in mitosis identical to those observed when ARK-1 function is blocked
- Thus, the ARK1-Bora-PLK1 regulatory circuit in mammalian cells elucidates a key mechanism in cell cycle regulation
- At least three isoforms of Bora are known to exist.
Compare Similar Items
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Antigen: Phospho-Bora (Ser497)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: BORA
Gene Alias: 6720463M24Rik; AI317232; aurora borealis; BORA; bora, aurora kinase A activator; C13orf34; HsBora; Protein aurora borealis; RGD1309522; RP11-342J4.2
Host Species: Rabbit
Purification Method: sequential chromatography
Regulatory Status: RUO
Gene ID (Entrez): 306102, 79866
Content And Storage: -20°C
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: Q5M864, Q6PGQ7
Gene Symbols: BORA
Immunogen: A synthesized peptide derived from human BORA(Accession Q6PGQ7), corresponding to amino acid residues around phosphorylated Ser497.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-Bora (Ser497)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
BORA
Gene Alias:
6720463M24Rik; AI317232; aurora borealis; BORA; bora, aurora kinase A activator; C13orf34; HsBora; Protein aurora borealis; RGD1309522; RP11-342J4.2
Host Species:
Rabbit
Purification Method:
sequential chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
306102, 79866
Content And Storage:
-20°C
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
Q5M864, Q6PGQ7
Gene Symbols:
BORA
Immunogen:
A synthesized peptide derived from human BORA(Accession Q6PGQ7), corresponding to amino acid residues around phosphorylated Ser497.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-Calpain 2 (Ser50)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CAPN2
Gene Alias: 80 kDa M-calpain subunit; AI326419; Calcium-activated neutral proteinase 2; calcium-dependent protease; CALP80; calpain 2; calpain 2, (m/II) large subunit; calpain 2, large [catalytic] subunit; calpain 2, large subunit; calpain II; calpain large polypeptide L2; Calpain M-type; calpain, large polypeptide L2; calpain-2 catalytic subunit; Calpain-2 large subunit; CANP 2; CANP2; CANPL2; CANPml; Capa2; Capa-2; CAPN2; cysteine proteinase; m-calpain; m-calpain 80 kDa large subunit; m-calpain large subunit; m-calpin; mCANP; millimolar-calpain
Host Species: Rabbit
Purification Method: sequential chromatography
Regulatory Status: RUO
Gene ID (Entrez): 12334, 29154, 824
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: O08529, P17655, Q07009
Gene Symbols: CAPN2
Immunogen: A synthesized peptide derived from human CAPN2(Accession P17655), corresponding to amino acid residues around phosphorylated Ser50.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-Calpain 2 (Ser50)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CAPN2
Gene Alias:
80 kDa M-calpain subunit; AI326419; Calcium-activated neutral proteinase 2; calcium-dependent protease; CALP80; calpain 2; calpain 2, (m/II) large subunit; calpain 2, large [catalytic] subunit; calpain 2, large subunit; calpain II; calpain large polypeptide L2; Calpain M-type; calpain, large polypeptide L2; calpain-2 catalytic subunit; Calpain-2 large subunit; CANP 2; CANP2; CANPL2; CANPml; Capa2; Capa-2; CAPN2; cysteine proteinase; m-calpain; m-calpain 80 kDa large subunit; m-calpain large subunit; m-calpin; mCANP; millimolar-calpain
Host Species:
Rabbit
Purification Method:
sequential chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
12334, 29154, 824
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
O08529, P17655, Q07009
Gene Symbols:
CAPN2
Immunogen:
A synthesized peptide derived from human CAPN2(Accession P17655), corresponding to amino acid residues around phosphorylated Ser50.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-CDX2 (Ser283)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CDX2
Gene Alias: caudal type homeo box 2; caudal type homeo box transcription factor 2; caudal type homeobox 2; caudal type homeobox transcription factor 2; caudal-type homeobox protein 2; CDX2; Cdx-2; CDX2/AS; CDX3; CDX-3; HGNC:1806; homeobox protein CDX-2; homeobox protein miniCDX2; homeobox transcription factor
Host Species: Rabbit
Purification Method: sequential chromatography
Regulatory Status: RUO
Gene ID (Entrez): 1045, 12591, 66019
Content And Storage: -20°C
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: P43241, Q99626
Gene Symbols: CDX2
Immunogen: A synthesized peptide derived from human CDX2(Accession Q99626), corresponding to amino acid residues around phosphorylated Ser283.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-CDX2 (Ser283)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CDX2
Gene Alias:
caudal type homeo box 2; caudal type homeo box transcription factor 2; caudal type homeobox 2; caudal type homeobox transcription factor 2; caudal-type homeobox protein 2; CDX2; Cdx-2; CDX2/AS; CDX3; CDX-3; HGNC:1806; homeobox protein CDX-2; homeobox protein miniCDX2; homeobox transcription factor
Host Species:
Rabbit
Purification Method:
sequential chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
1045, 12591, 66019
Content And Storage:
-20°C
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
P43241, Q99626
Gene Symbols:
CDX2
Immunogen:
A synthesized peptide derived from human CDX2(Accession Q99626), corresponding to amino acid residues around phosphorylated Ser283.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-Claudin 1 (Tyr210)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CLDN1
Gene Alias: AI596271; claudin 1; claudin-1; CLD1; CLDN1; hypothetical protein; ILVASC; SEMP1; Senescence-associated epithelial membrane protein; senescence-associated epithelial membrane protein 1; tight junction protein; UNQ481/PRO944
Host Species: Rabbit
Purification Method: sequential chromatography
Regulatory Status: RUO
Gene ID (Entrez): 12737, 65129, 9076
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: O88551, O95832, P56745
Gene Symbols: CLDN1
Immunogen: A synthesized peptide derived from human CLDN1(Accession O95832), corresponding to amino acid residues around phosphorylated Tyr210.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-Claudin 1 (Tyr210)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CLDN1
Gene Alias:
AI596271; claudin 1; claudin-1; CLD1; CLDN1; hypothetical protein; ILVASC; SEMP1; Senescence-associated epithelial membrane protein; senescence-associated epithelial membrane protein 1; tight junction protein; UNQ481/PRO944
Host Species:
Rabbit
Purification Method:
sequential chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
12737, 65129, 9076
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
O88551, O95832, P56745
Gene Symbols:
CLDN1
Immunogen:
A synthesized peptide derived from human CLDN1(Accession O95832), corresponding to amino acid residues around phosphorylated Tyr210.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG