PIPA5106040

Phospho-SPHK1 (Ser225) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA5106040-Each-of-1 In Stock ₹ 44,705.10

PIPA5106040 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

Phospho-SPHK1 (Ser225)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

SPHK1

Gene Alias

1110006G24Rik; Acetyltransferase SPHK1; RP23-193A16.4; SK 1; Sk1; SKase; Sphingosine kinase 1; SPHK; SPHK1; SPK; SPK 1; Spk1

Host Species

Rabbit

Purification Method

sequential chromatography

Regulatory Status

RUO

Gene ID (Entrez)

8877

Content And Storage

-20°C

Form

Liquid

Applications

Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

Q9NYA1

Gene Symbols

SPHK1

Immunogen

A synthesized peptide derived from human SPHK1(Accession Q9NYA1), corresponding to amino acid residues around phosphorylated Ser225.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of SPHK1 only when phosphorylated at Ser225
  • SPHK1, along with SPHK2, catalyzes the phosphorylation of sphingosine producing the signaling molecule sphingosine-1-phosphate (S1P)
  • S1P signals through G-protein coupled receptors and controls diverse cellular processes
  • Inhibitors of SPHKs are viewed as potential therapeutics for the treatment of cancer
  • SPHK1 catalyzes the phosphorylation of sphingosine to sphingosine 1 phosphate (S1P), an important signaling molecule with intra- and extracellular functions
  • Inside the cell S1P acts as a signaling molecule like other sphingolipid metabolites like ceramide and sphingosine
  • S1P has been implicated in regulating cell differentiation, calcium mobilization from intracellular stores, and apoptosis
  • The cell surface receptors for S1P are the EDG family of G protein-coupled receptors (S1P Receptors).

Compare Similar Items

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Thermo Scientific

PIPA5106040

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Antigen:
Phospho-SPHK1 (Ser225)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SPHK1

Gene Alias:
1110006G24Rik; Acetyltransferase SPHK1; RP23-193A16.4; SK 1; Sk1; SKase; Sphingosine kinase 1; SPHK; SPHK1; SPK; SPK 1; Spk1

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
8877

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q9NYA1

Gene Symbols:
SPHK1

Immunogen:
A synthesized peptide derived from human SPHK1(Accession Q9NYA1), corresponding to amino acid residues around phosphorylated Ser225.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA5106042

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Antigen:
Phospho-SREBP2 (Ser455)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SREBF2

Gene Alias:
AI608257; bHLHd2; Class D basic helix-loop-helix protein 2; EMBL:AAI01903.1}; lop13; nuc; Processed sterol regulatory element-binding protein 2; srebf2; srebf2 {ECO:0000312; Srebf2_retired; SREBP2; SREBP-2; SREBP2gc; sterol regulatory element binding factor 2; sterol regulatory element binding protein 2; sterol regulatory element binding transcription factor 2; sterol regulatory element-binding protein 2; Sterol regulatory element-binding transcription factor 2; zgc:158371

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20788, 300095, 6721

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q12772, Q3T1I5, Q3U1N2

Gene Symbols:
SREBF2

Immunogen:
A synthesized peptide derived from human SREBF2(Accession Q12772), corresponding to amino acid residues around phosphorylated Ser455.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5106044

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Antigen:
Phospho-NR5A1 (Ser203)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Nr5a1

Gene Alias:
Ad4BP; Ad4BP/SF-1; adrenal 4 binding protein; Adrenal 4 binding protein (AD4BP); adrenal 4-binding protein; ELP; ELP-3; Embryonal long terminal repeat-binding protein; embryonal LTR-binding protein; FTZ1; FTZF1; Ftz-F1; fushi tarazu 1 factor homolog; fushi tarazu factor homolog 1; Fushi tarazu factor homolog 1 (FTZ1); hSF-1; Nr5a1; nuclear receptor AdBP4; nuclear receptor subfamily 5 group A member 1; Nuclear receptor subfamily 5 group A member 1 (NR5A1); nuclear receptor subfamily 5, group A, member 1; POF7; SF1; SF-1; SPGF8; SRXY3; Steroid hormone receptor Ad4BP; steroid hydroxylase positive regulator; Steroidogenic factor 1; Steroidogenic factor 1 (SF1); steroidogenic factor 1 nuclear receptor; steroidogenic factor-1; STF1; STF-1

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2516, 26423, 83826

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P33242, P50569, Q13285

Gene Symbols:
Nr5a1

Immunogen:
A synthesized peptide derived from human NR5A1(Accession Q13285), corresponding to amino acid residues around phosphorylated Ser203.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5106049

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Antigen:
Phospho-TLR5 (Tyr798)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TLR5

Gene Alias:
FLJ10052; MELIOS; MGC126430; MGC126431; RP11-239E10.1; SLE1; SLEB1; systemic lupus erythematosus susceptibility 1; TIL3; Tlr5; toll like receptor 5; Toll/interleukin-1 receptor-like protein 3; toll-like receptor 5

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
53791, 7100

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O60602, Q9JLF7

Gene Symbols:
TLR5

Immunogen:
A synthesized peptide derived from human TLR5(Accession O60602), corresponding to amino acid residues around phosphorylated Tyr798.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG