PIPA5106055

Phospho-VHL (Ser68) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5106055-Each-of-1 In Stock ₹ 44,705.10

PIPA5106055 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

Phospho-VHL (Ser68)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

VHL

Gene Alias

elongin binding protein; HRCA1; Protein G7; pVHL; RCA1; VHL; VHL1; VHL19; Vhlh; VHLp18(MEA); Von Hippel Lindau; von hippel-lindau; von Hippel-Lindau disease tumor suppressor; von Hippel-Lindau syndrome homolog; von Hippel-Lindau syndrome protein homolog; von Hippel-Lindau tumor suppressor; von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase

Host Species

Rabbit

Purification Method

sequential chromatography

Regulatory Status

RUO

Gene ID (Entrez)

22346, 24874, 7428

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

P40337, P40338, Q64259

Gene Symbols

VHL

Immunogen

A synthesized peptide derived from human VHL(Accession P40337), corresponding to amino acid residues around phosphorylated Ser68.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of VHL only when phosphorylated at Ser68
  • Von Hippel-Lindau syndrome (VHL) is a dominantly inherited familial cancer syndrome predisposing to a variety of malignant and benign tumors
  • A germline mutation of this gene is the basis of familial inheritance of VHL syndrome
  • The protein encoded by this gene is a component of the protein complex that includes elongin B, elongin C, and cullin-2, and possesses ubiquitin ligase E3 activity
  • This protein is involved in the ubiquitination and degradation of hypoxia-inducible-factor (HIF), which is a transcription factor that plays a central role in the regulation of gene expression by oxygen
  • RNA polymerase II subunit POLR2G/RPB7 is also reported to be a target of this protein
  • Alternatively spliced transcript variants encoding distinct isoforms have been observed.

Compare Similar Items

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Img

Thermo Scientific

PIPA5106055

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Antigen:
Phospho-VHL (Ser68)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
VHL

Gene Alias:
elongin binding protein; HRCA1; Protein G7; pVHL; RCA1; VHL; VHL1; VHL19; Vhlh; VHLp18(MEA); Von Hippel Lindau; von hippel-lindau; von Hippel-Lindau disease tumor suppressor; von Hippel-Lindau syndrome homolog; von Hippel-Lindau syndrome protein homolog; von Hippel-Lindau tumor suppressor; von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
22346, 24874, 7428

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P40337, P40338, Q64259

Gene Symbols:
VHL

Immunogen:
A synthesized peptide derived from human VHL(Accession P40337), corresponding to amino acid residues around phosphorylated Ser68.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5106060

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Antigen:
Phospho-ALK (Tyr1586)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ALK

Gene Alias:
Alk; ALK tyrosine kinase receptor; ALK/NPM1 fusion gene; anaplastic lymphoma kinase; Anaplastic lymphoma kinase Ki1; Anaplastic Lymphoma Kinase p80; anaplastic lymphoma receptor tyrosine kinase; CD246; CD246 antigen; EC 2.7.10.1; kinase ALK; mutant anaplastic lymphoma kinase; NBLST3; npm-alk; p80; Tcrz; TFG/ALK

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11682, 238

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P97793, Q9UM73

Gene Symbols:
ALK

Immunogen:
A synthesized peptide derived from human ALK(Accession Q9UM73), corresponding to amino acid residues around phosphorylated Tyr1586.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5106062

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Antigen:
Phospho-IP3 Receptor 1 (Tyr353)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Itpr1

Gene Alias:
ACV; CLA4; D6Pas2; ENSMUSG00000072853; Gm10429; I145TR; inositol 1,4,5-triphosphate receptor 1; inositol 1,4,5-triphosphate receptor, type 1; inositol 1,4,5-trisphosphate receptor 1; inositol 1,4,5-trisphosphate receptor type 1; inositol 1,4,5-trisphosphate receptor, type 1; inositol 1,4,5-trisphosphate-binding protein P400; InsP>3<R type I; Insp3r; InsP3R type I; insP3R1; IP3 receptor; IP3 receptor isoform 1; Ip3r; IP-3-R; IP3R 1; IP3R1; Itpr1; Itpr-1; opisthotonus; opt; P400; Pcd6; Pcp1; Pcp-1; PPP1R94; protein PCD-6; protein phosphatase 1, regulatory subunit 94; Purkinje cell protein 1; SCA15; SCA16; SCA29; SI-SIII-SIIA; Type 1 inositol 1,4,5-trisphosphate receptor; type 1 InsP3 receptor

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16438, 25262, 3708

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P11881, P29994, Q14643

Gene Symbols:
Itpr1

Immunogen:
A synthesized peptide derived from human ITPR1(Accession Q14643), corresponding to amino acid residues around phosphorylated Tyr353.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5106064

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Antigen:
Phospho-LRP6 (Ser1490)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
LRP6

Gene Alias:
ADCAD2; C030016K15Rik; Cd; crooked; FLJ90062; FLJ90421; Gw; LDL receptor related protein 6; low density lipoprotein receptor-related protein 6; low density lipoprotein receptor-related protein 6; low density lipoprotein-related protein 6; low density lipoprotein-related protein 6; low-density lipoprotein receptor-related protein 6; lpr6; LRP6; LRP-6; ska<m26Jus>; ska26; skax26; STHAG7

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16974, 4040

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O75581, O88572

Gene Symbols:
LRP6

Immunogen:
A synthesized peptide derived from human LRP6(Accession O75581), corresponding to amino acid residues around phosphorylated Ser1490.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG