PIPA5106064

Phospho-LRP6 (Ser1490) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA5106064-Each-of-1 In Stock ₹ 43,592.82

PIPA5106064 - Each of 1

₹ 43,592.82

In Stock

Quantity

1

Base Price: ₹ 43,592.82

GST (18%): ₹ 7,846.708

Total Price: ₹ 51,439.528

Antigen

Phospho-LRP6 (Ser1490)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

LRP6

Gene Alias

ADCAD2; C030016K15Rik; Cd; crooked; FLJ90062; FLJ90421; Gw; LDL receptor related protein 6; low density lipoprotein receptor-related protein 6; low density lipoprotein receptor-related protein 6; low density lipoprotein-related protein 6; low density lipoprotein-related protein 6; low-density lipoprotein receptor-related protein 6; lpr6; LRP6; LRP-6; ska<m26Jus>; ska26; skax26; STHAG7

Host Species

Rabbit

Purification Method

sequential chromatography

Regulatory Status

RUO

Gene ID (Entrez)

16974, 4040

Content And Storage

-20°C

Form

Liquid

Applications

Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

O75581, O88572

Gene Symbols

LRP6

Immunogen

A synthesized peptide derived from human LRP6(Accession O75581), corresponding to amino acid residues around phosphorylated Ser1490.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of LRP6 only when phosphorylated at Ser1490
  • LRP6 is essential for the Wnt/beta catenin signaling pathway, probably by acting as a coreceptor together with Frizzled for Wnt
  • It is a specific, high-affinity receptor for DKK1 and DKK2, but not DKK3
  • The interaction with DKK1 blocks LRP6-mediated Wnt/beta catenin signaling via LRP6 removal via Kremen proteins-mediated endocytosis.

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PIPA5106064

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Antigen:
Phospho-LRP6 (Ser1490)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
LRP6

Gene Alias:
ADCAD2; C030016K15Rik; Cd; crooked; FLJ90062; FLJ90421; Gw; LDL receptor related protein 6; low density lipoprotein receptor-related protein 6; low density lipoprotein receptor-related protein 6; low density lipoprotein-related protein 6; low density lipoprotein-related protein 6; low-density lipoprotein receptor-related protein 6; lpr6; LRP6; LRP-6; ska<m26Jus>; ska26; skax26; STHAG7

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16974, 4040

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O75581, O88572

Gene Symbols:
LRP6

Immunogen:
A synthesized peptide derived from human LRP6(Accession O75581), corresponding to amino acid residues around phosphorylated Ser1490.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

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PIPA5106066

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Antigen:
Phospho-PFKFB2 (Ser466)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Pfkfb2

Gene Alias:
4930568D07Rik; 6PF-2-K/Fru-2,6-P2ase 2; 6PF-2-K/Fru-2,6-P2ase heart-type isozyme; 6-phosphofructo-2-kinase; 6-phosphofructo-2-kinase /fructose-2,6-bisphosphatase; 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase; 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2; 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2; 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2; 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2; 6-Phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 (heart); 6-phosphofructo-2-kinase/fructose2,6-bisphosphatase isoenzyme 2; fructose 6-P,2-kinase:fructose 2,6-bisphosphatase; fructose 6-phosphate 2-kinase/fructose 2,6-bisphosphatase; fructose 6-phosphate, 2-kinase:fructose 2,6-bisphosphatase; fructose 6-phosphate,2-kinase:fructose 2, 6-bisphosphatase; Fructose-2,6-bisphosphatase; fructose-2,6-bisphosphatase, cardiac isozyme; PFK/FBPase 2; PFK-2 car; PFK-2 cardiac; PFK-2/FBPase-2; PFK-2/FBPase-2 gene B; PFKFB, cardiac; PFKFB2; RH2K

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18640, 24640, 5208

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O60825, P70265, Q9JJH5

Gene Symbols:
Pfkfb2

Immunogen:
A synthesized peptide derived from human PFKFB2(Accession O60825), corresponding to amino acid residues around phosphorylated Ser466.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA5106067

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Antigen:
Phospho-POLR2A (Ser1616)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
POLR2A

Gene Alias:
220kDa; DNA polymerase epsilon catalytic subunit; DNA polymerase epsilon catalytic subunit A; DNA polymerase II subunit A; DNA-directeced RNA polymerase II polypeptide A; DNA-directed RNA polymerase II largest subunit, RNA polymerase II 220 kd subunit; DNA-directed RNA polymerase II subunit A; DNA-directed RNA polymerase II subunit RPB1; DNA-directed RNA polymerase III largest subunit; DUN2; EC 2.7.7.6; hRPB220; hsRPB1; MGC75453; N0825; Pol II S2p; POL2; POLR2; Polr2a; POLRA; Polymerase (RNA II (DNA directed), large polypeptide; polymerase (RNA) II (DNA directed) polypeptide A; polymerase (RNA) II (DNA directed) polypeptide A (220kD); polymerase (RNA) II (DNA directed) polypeptide A, 220kDa; polymerase (RNA) II subunit A; POLYMERASE II; RNA; RNA POL2; RNA polymerase II 1; RNA polymerase II subunit A; RNA polymerase II subunit B1; RNA-directed RNA polymerase II subunit RPB1; RP02; RPB1; RPB220; RPBh1; Rpii215; RpIILS; RPO2; RPO21; Rpo2-1; RPOL2; SUA8; YNL262W

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20020, 363633, 5430

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P08775, P24928

Gene Symbols:
POLR2A

Immunogen:
A synthesized peptide derived from human POLR2A(Accession P24928), corresponding to amino acid residues around phosphorylated Ser1616.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA5106070

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Antigen:
Phospho-Cardiac Troponin I (Ser23, Ser24)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TNNI3

Gene Alias:
alternatively spliced; cardiac ankyrin repeat kinase; Cardiac muscle troponin T; cardiac troponin I; cardiac troponin I isoform; cardiac troponin I-interacting kinase; cardiac troponin T; cardiac troponin T isoform 1; cardiac troponin T isoform 2; cardiac troponin T2; cardiomyopathy, dilated 1D (autosomal dominant); cardiomyopathy, dilated 2A (autosomal recessive); cardiomyopathy, hypertrophic 2; CARK; CCDD; CMD1D; CMD1FF; CMD2A; CMH2; CMH7; CMPD2; cTnI; cTnT; Ctt; CTTG; D830019J24Rik; LVNC6; MGC116817; RATCTTG; RCM1; RCM3; Serine/threonine-protein kinase TNNI3K; Tn1; TnI; TNNC1; Tnni3; TNNI3 interacting kinase; TNNI3-interacting kinase; TNNI3K; tnni3k {ECO:0000250; TNNT2; Tnnt3; TnTc; Tpn1; troponin 1, type 3; troponin I type 3 (cardiac); troponin I, cardiac 3; troponin I, cardiac muscle; troponin I, cardiac muscle-like; troponin I3, cardiac type; Troponin T cardiac; troponin T cardiac isoform; troponin T isoform 1; troponin T isoform 2; troponin T splicing mutant isoform 1; troponin

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
21954, 29248, 7137

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P19429, P23693, P48787

Gene Symbols:
TNNI3

Immunogen:
A synthesized peptide derived from human TNNI3(Accession P19429), corresponding to amino acid residues around phosphorylated Ser23.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG