PIPA5106248

JAK2/JAK3 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5106248-Each-of-1 In Stock ₹ 39,999.30

PIPA5106248 - Each of 1

₹ 39,999.30

In Stock

Quantity

1

Base Price: ₹ 39,999.30

GST (18%): ₹ 7,199.874

Total Price: ₹ 47,199.174

Antigen

JAK2/JAK3

Classification

Polyclonal

Conjugate

Unconjugated

Gene

JAK2

Gene Alias

Breast-JAK3; fae; Fd17; JAK2; JAK-2; JAK3; JAK-3; JAK3_HUMAN; JAK3B; JAKL; Janus kinase 2; Janus kinase 2 (a protein tyrosine kinase); Janus kinase 3; Janus kinase 3 (a protein tyrosine kinase, leukocyte); Janus kinase 3 protein-tyrosine kinase; Janus kinase 3, protein-tyrosine kinase; JTK10; Leukocyte janus kinase; LJAK; L-JAK; RATJAK3; THCYT3; tyrosine-protein kinase JAK2; Tyrosine-protein kinase JAK3; wil

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

16452, 16453, 24514, 25326, 3717, 3718

Content And Storage

-20°C

Form

Liquid

Applications

Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

O60674, P52333, Q62120, Q62137, Q62689, Q63272

Gene Symbols

JAK2, JAK3

Immunogen

A synthesized peptide derived from human JAK2(Accession O60674), corresponding to amino acid residues Y940-V990.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Related Products

Img

Thermo Scientific

PIPA5105891

--

Img

Thermo Scientific

PIPA5105892

--

Img

Thermo Scientific

PIPA5105871

--

Img

Thermo Scientific

PIPA5105534

--

Img

Thermo Scientific

PIPA5105867

--

Img

Thermo Scientific

PIPA5105566

--

Img

Thermo Scientific

PIPA5106238

--

Img

Thermo Scientific

PIPA5105885

--

Description

  • Antibody detects endogenous levels of total JAK2/3
  • Janus Activating Kinase 2 and 3 (JAK2/JAK3) is one of a number of related tyrosine kinases involved in cytoplasmic signal transduction
  • In response to a varitety of cytokine or related factors (e.g., interferon, interleukins), JAKs are activated via phosphorylation at 2 adjacent tyrosine residues
  • The activation of JAKs can lead to the phosphorylation of STAT (signal transducers and activatiors of transcription) proteins, which dimerize and translocate to the nucleus
  • Once translocated to the nucleus, the STAT proteins can modify transcription of numerous genes, including interferon-stimulated genes
  • JAK2 is required for the IFN gamma-receptor complex initiation and JAK1 functions as an amplifier
  • However, active JAK1 may be required for complex responses
  • Some studies have suggested that the role of JAK2 might be performed by Tyk2 and JAK3, if they were positioned correctly within the IFN gamma-receptor complex.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA5106248

--


Antigen:
JAK2/JAK3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
JAK2

Gene Alias:
Breast-JAK3; fae; Fd17; JAK2; JAK-2; JAK3; JAK-3; JAK3_HUMAN; JAK3B; JAKL; Janus kinase 2; Janus kinase 2 (a protein tyrosine kinase); Janus kinase 3; Janus kinase 3 (a protein tyrosine kinase, leukocyte); Janus kinase 3 protein-tyrosine kinase; Janus kinase 3, protein-tyrosine kinase; JTK10; Leukocyte janus kinase; LJAK; L-JAK; RATJAK3; THCYT3; tyrosine-protein kinase JAK2; Tyrosine-protein kinase JAK3; wil

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16452, 16453, 24514, 25326, 3717, 3718

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O60674, P52333, Q62120, Q62137, Q62689, Q63272

Gene Symbols:
JAK2, JAK3

Immunogen:
A synthesized peptide derived from human JAK2(Accession O60674), corresponding to amino acid residues Y940-V990.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5106249

--


Antigen:
MEKK2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Map3k2

Gene Alias:
2.7.11.25; 9630061B06Rik; AI585793; MAP/ERK kinase kinase 2; MAP3K2; MAPK/ERK kinase kinase 2; MAPKKK2; MEK kinase 2; MEKK 2; MEKK2; MEKK2B; mitogen activated protein kinase kinase kinase 2; mitogen-activated protein kinase kinase kinase 2; protein kinase MEKK2b

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10746, 171492, 26405

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q61083, Q9Y2U5

Gene Symbols:
Map3k2

Immunogen:
A synthesized peptide derived from human MAP3K2(Accession Q9Y2U5), corresponding to amino acid residues S493-D543.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5106250

--


Antigen:
MSK2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Rps6ka4

Gene Alias:
1110069D02Rik; 90 kDa ribosomal protein S6 kinase 4; 90kDa; AI848992; Ccdc88b; coiled-coil domain containing 88B; EC 2.7.11.1; kinase MSK2; KS6A4; mitogen- and stress-activated protein kinase 2; mitogen- and stress-activated protein kinase-2; mMSK2; MSK2; Nuclear mitogen- and stress-activated protein kinase 2; ribosomal protein kinase B; ribosomal protein S6 kinase A4; ribosomal protein S6 kinase alpha 4; ribosomal protein S6 kinase alpha-4; ribosomal protein S6 kinase, 90kD, polypeptide 4; ribosomal protein S6 kinase, 90kDa, polypeptide 4; ribosomal protein S6 kinase, polypeptide 4; RLSK; RPS6KA4; RSKB; RSK-B; RSK-like protein kinase; S6K-alpha-4

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
361715, 56613, 8986

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O75676, Q9Z2B9

Gene Symbols:
Rps6ka4

Immunogen:
A synthesized peptide derived from human RPS6KA4(Accession O75676), corresponding to amino acid residues D170-D220.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5106251

--


Antigen:
STK38/STK38L

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Stk38

Gene Alias:
4930473A22Rik; 5830476G13Rik; 9530097A09Rik; AA617404; B230328I19; KIAA0965; NDR; Ndr Ser/Thr kinase-like protein; NDR1; NDR1 protein kinase; NDR2; NDR2 protein kinase; Ndr54; nuclear Dbf2-related 2; nuclear Dbf2-related kinase 1; Nuclear Dbf2-related kinase 2; RGD1564793; serine/threonine kinase 38; serine/threonine kinase 38 like; serine/threonine kinase 38-like; serine/threonine-protein kinase 38; Serine/threonine-protein kinase 38-like; stk38; Stk38l

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
106504, 11329, 23012, 232533, 361813, 691337

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q15208, Q7TSE6, Q91VJ4, Q9Y2H1

Gene Symbols:
Stk38, STK38L

Immunogen:
A synthesized peptide derived from human STK38(Accession Q15208), corresponding to amino acid residues V423-K465.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG