PIPA5106252

ARK5 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5106252-Each-of-1 In Stock ₹ 44,705.10

PIPA5106252 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

ARK5

Classification

Polyclonal

Conjugate

Unconjugated

Gene

NUAK1

Gene Alias

AMP-activated protein kinase family member 5; AMPK-related protein kinase 5; ARK5; AU014801; AW494241; B230104P22Rik; I79_017442; KIAA0537; NUAK family kinase 1; NUAK family SNF1-like kinase 1; NUAK family, SNF1-like kinase, 1; Nuak1; Omphalocele kinase 1; Omphk1; RGD1309956; ZNUAK family, SNF1-like kinase, 1

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

299694, 77976, 9891

Content And Storage

-20°C

Form

Liquid

Applications

Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

O60285, Q641K5

Gene Symbols

NUAK1

Immunogen

A synthesized peptide derived from human NUAK1(Accession O60285), corresponding to amino acid residues D575-L625.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total NuaK1
  • NUAK1 (ARK5) is a serine/threonine kinase that plays a role in many cellular functions
  • The overexpression of this kinase has been associated with tumor invasion and metastasis (colorectal neoplasm)
  • Acts as a regulator of cellular senescence and cellular ploidy by mediating phosphorylation of 'Ser-464' of LATS1, thereby controlling its stability
  • Controls cell adhesion by regulating activity of the myosin protein phosphatase 1 (PP1) complex
  • Acts by mediating phosphorylation of PPP1R12A subunit of myosin PP1: phosphorylated PPP1R12A then interacts with 14-3-3, leading to reduced dephosphorylation of myosin MLC2 by myosin PP1
  • May be involved in DNA damage response: phosphorylates p53/TP53 at 'Ser-15' and 'Ser-392' and is recruited to the CDKN1A/WAF1 promoter to participate in transcription activation by p53/TP53
  • May also act as a tumor malignancy-associated factor by promoting tumor invasion and metastasis under regulation and phosphorylation by AKT1
  • Suppresses Fas-induced apoptosis by mediating phosphorylation of CASP6, thereby suppressing the activation of the caspase and the subsequent cleavage of CFLAR
  • Regulates UV radiation-induced DNA damage response mediated by CDKN1A
  • In association with STK11, phosphorylates CDKN1A in response to UV radiation and contributes to its degradation which is necessary for optimal DNA repair.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA5106252

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Antigen:
ARK5

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NUAK1

Gene Alias:
AMP-activated protein kinase family member 5; AMPK-related protein kinase 5; ARK5; AU014801; AW494241; B230104P22Rik; I79_017442; KIAA0537; NUAK family kinase 1; NUAK family SNF1-like kinase 1; NUAK family, SNF1-like kinase, 1; Nuak1; Omphalocele kinase 1; Omphk1; RGD1309956; ZNUAK family, SNF1-like kinase, 1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
299694, 77976, 9891

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O60285, Q641K5

Gene Symbols:
NUAK1

Immunogen:
A synthesized peptide derived from human NUAK1(Accession O60285), corresponding to amino acid residues D575-L625.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5106253

--


Antigen:
p38 MAPK gamma/delta

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MAPK12

Gene Alias:
AW123708; ERK3; ERK6; ERK-6; Exon skip; extracellular signal-regulated kinase 6; MAP kinase 12; MAP kinase 13; MAP kinase p38 delta; MAP kinase p38 gamma; MAPK 12; MAPK 13; MAPK12; MAPK13; MAPK-13; mitogen activated protein kinase 12; mitogen activated protein kinase 13; mitogen-activated protein kinase 12; Mitogen-activated protein kinase 13; mitogen-activated protein kinase 3; mitogen-activated protein kinase p38 delta; Mitogen-activated protein kinase p38 gamma; p38 delta MAP kinase; p38delta; P38GAMMA; PRKM12; Prkm13; SAP kinase-3; SAPK/Erk/kinase 4; SAPK3; SAPK-3; SAPK4; Serk4; stress activated protein kinase 3; stress-activated protein kinase 3; Stress-activated protein kinase 4

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
26415, 29857, 5603, 6300

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O08911, O15264, P53778, Q9Z1B7

Gene Symbols:
MAPK12, MAPK13

Immunogen:
A synthesized peptide derived from human MAPK12(Accession P53778), corresponding to amino acid residues N162-V212.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5106254

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Antigen:
SIK1/SIK2/SIK3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SIK1

Gene Alias:
QIK, QSK

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
150094, 17691, 23235, 23387, 235344, 315649, 59329, 684112, 70661

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P57059, Q60670, Q6P4S6, Q8CFH6, Q9H0K1, Q9R1U5, Q9Y2K2

Gene Symbols:
SIK1, SIK2, SIK3

Immunogen:
A synthesized peptide derived from human SIK1(Accession P57059), corresponding to amino acid residues K164-L214.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5106255

--


Antigen:
ROS1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ROS1

Gene Alias:
c-ros; c-ros oncogene 1 , receptor tyrosine kinase; c-Ros receptor tyrosine kinase; c-ros-1; heart - derived c - ros - 1 proto - oncogene; MCF3; Proto-oncogene c-Ros; proto-oncogene c-Ros-1; Proto-oncogene tyrosine-protein kinase ROS; receptor tyrosine kinase c-ros oncogene 1; ROS; ROS proto-oncogene 1 , receptor tyrosine kinase; ROS proto-oncogene 1, receptor tyrosine kinase; Ros1; Ros-1; Ros1 proto-oncogene; ROS1C; RP1-179P9.1; transmembrane tyrosine-specific protein kinase; v-ros avian UR2 sarcoma virus oncogene homolog 1; v-ros UR2 sarcoma virus oncogene homolog 1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
25346, 6098

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P08922, Q63132

Gene Symbols:
ROS1

Immunogen:
A synthesized peptide derived from human ROS1(Accession P08922), corresponding to amino acid residues D2249-S2299.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG