PIPA5106710
PMS2/PMS2CL Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5106710-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA5106710 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
PMS2/PMS2CL
Classification
Polyclonal
Conjugate
Unconjugated
Gene
PMS2
Gene Alias
DNA mismatch repair protein PMS2; H_DJ0042M02.9; HNPCC4; mismatch repair endonuclease PMS2; MLH4; PMS1 homolog 2, mismatch repair protein; PMS1 homolog 2, mismatch repair system component; PMS1 protein homolog 2; PMS2; PMS2 C-terminal like pseudogene; PMS2 postmeiotic segregation increased 2; PMS2CL; PMS2P13; PMSL2; postmeiotic segregation increased 2 nirs variant 6
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
441194, 5395
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
P54278, Q68D20
Gene Symbols
PMS2, PMS2CL
Immunogen
A synthesized peptide derived from human PMS2CL(Accession Q68D20), corresponding to amino acid residues D124-C174.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of total PMS2/PMS2CL
- Mismatch DNA repair in bacteria is carried out by the MutL, MutH, and MutS proteins
- The MutS protein initially binds to mismatched DNA
- This is followed by binding of the MutH endonuclease and MutL to form a complex that carries out excision repair
- The hMSH2 gene specifies a MutS homologue and hMLH1, hPMS1, and hPMS2 encode MutL homologs
- Mutations in these genes are associated with hereditary nonpolyposis colon cancer (HNPCC), one of the most common hereditary diseases in man
- As with the bacterial system, HNPCC is characterized by frequent microsatellite mutations that arise by somatic mutation due to a replication error (RER+) phenotype
- Both hPMS1 and hPMS2 are mutated in the germline of HNPCC patients
- Although the exact function of MutL and its homologs has yet to be determined, it is known that a complex of PMS2 and MLH1 (MutLa) from HeLa cells can complement a deficiency of MLH1 in hypermutable H6 colorectal tumor cells.
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Antigen: PMS2/PMS2CL
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PMS2
Gene Alias: DNA mismatch repair protein PMS2; H_DJ0042M02.9; HNPCC4; mismatch repair endonuclease PMS2; MLH4; PMS1 homolog 2, mismatch repair protein; PMS1 homolog 2, mismatch repair system component; PMS1 protein homolog 2; PMS2; PMS2 C-terminal like pseudogene; PMS2 postmeiotic segregation increased 2; PMS2CL; PMS2P13; PMSL2; postmeiotic segregation increased 2 nirs variant 6
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 441194, 5395
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: P54278, Q68D20
Gene Symbols: PMS2, PMS2CL
Immunogen: A synthesized peptide derived from human PMS2CL(Accession Q68D20), corresponding to amino acid residues D124-C174.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
PMS2/PMS2CL
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PMS2
Gene Alias:
DNA mismatch repair protein PMS2; H_DJ0042M02.9; HNPCC4; mismatch repair endonuclease PMS2; MLH4; PMS1 homolog 2, mismatch repair protein; PMS1 homolog 2, mismatch repair system component; PMS1 protein homolog 2; PMS2; PMS2 C-terminal like pseudogene; PMS2 postmeiotic segregation increased 2; PMS2CL; PMS2P13; PMSL2; postmeiotic segregation increased 2 nirs variant 6
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
441194, 5395
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
P54278, Q68D20
Gene Symbols:
PMS2, PMS2CL
Immunogen:
A synthesized peptide derived from human PMS2CL(Accession Q68D20), corresponding to amino acid residues D124-C174.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: MOV10L1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MOV10L1
Gene Alias: Cardiac helicase activated by MEF2 protein; cardiac helicase activated by MEF2C protein; cardiac-specific RNA helicase; Champ; Csm; DJ402G11.8; Moloney leukemia virus 10-like 1; moloney leukemia virus 10-like protein 1; Moloney leukemia virus 10-like protein 1 homolog; Mov10 RISC complex RNA helicase like 1; Mov10l1; Mov10l1, Moloney leukemia virus 10-like 1, homolog; Mov10-like 1; MOV10-like protein 1; MOV10-like protein 1 homolog; putative helicase Mov10l1; RNA helicase Mov10l1
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 300141, 54456, 83456
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: Q99MV5, Q9BXT6
Gene Symbols: MOV10L1
Immunogen: A synthesized peptide derived from human MOV10L1(Accession Q9BXT6), corresponding to amino acid residues Q317-L367.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
MOV10L1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MOV10L1
Gene Alias:
Cardiac helicase activated by MEF2 protein; cardiac helicase activated by MEF2C protein; cardiac-specific RNA helicase; Champ; Csm; DJ402G11.8; Moloney leukemia virus 10-like 1; moloney leukemia virus 10-like protein 1; Moloney leukemia virus 10-like protein 1 homolog; Mov10 RISC complex RNA helicase like 1; Mov10l1; Mov10l1, Moloney leukemia virus 10-like 1, homolog; Mov10-like 1; MOV10-like protein 1; MOV10-like protein 1 homolog; putative helicase Mov10l1; RNA helicase Mov10l1
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
300141, 54456, 83456
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
Q99MV5, Q9BXT6
Gene Symbols:
MOV10L1
Immunogen:
A synthesized peptide derived from human MOV10L1(Accession Q9BXT6), corresponding to amino acid residues Q317-L367.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: PDK1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PDK1
Gene Alias: [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial; [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial; B830012B01; D530020C15Rik; isoenzyme 1; kinase isoenzyme 1; lipoamide; mitochondrial pyruvate dehydrogenase, lipoamide, kinase isoenzyme 1; PDH kinase 1; PDHK1; PDK p48; Pdk1; pyruvate dehydrogenase; pyruvate dehydrogenase kinase 1; Pyruvate dehydrogenase kinase isoform 1; pyruvate dehydrogenase kinase, isoenzyme 1; pyruvate dehydrogenase kinase, isozyme 1
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 116551, 228026, 5163
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: Q15118, Q63065, Q8BFP9
Gene Symbols: PDK1
Immunogen: A synthesized peptide derived from human PDK1(Accession Q15118), corresponding to amino acid residues L102-V152.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
PDK1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PDK1
Gene Alias:
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial; [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial; B830012B01; D530020C15Rik; isoenzyme 1; kinase isoenzyme 1; lipoamide; mitochondrial pyruvate dehydrogenase, lipoamide, kinase isoenzyme 1; PDH kinase 1; PDHK1; PDK p48; Pdk1; pyruvate dehydrogenase; pyruvate dehydrogenase kinase 1; Pyruvate dehydrogenase kinase isoform 1; pyruvate dehydrogenase kinase, isoenzyme 1; pyruvate dehydrogenase kinase, isozyme 1
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
116551, 228026, 5163
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
Q15118, Q63065, Q8BFP9
Gene Symbols:
PDK1
Immunogen:
A synthesized peptide derived from human PDK1(Accession Q15118), corresponding to amino acid residues L102-V152.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: RRAGB
Classification: Polyclonal
Conjugate: Unconjugated
Gene: RRAGB
Gene Alias: bA465E19.1, GTP-binding protein ragB, LOC100724885, Rag B, RAGB, Ras related GTP binding B, Ras-related GTP binding B, ras-related GTP-binding protein A, ras-related GTP-binding protein B, ras-related GTP-binding protein B, RGD:619805}, RRAGB, rragB {ECO:0000312
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 10325, 117043, 245670
Content And Storage: -20°C
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: Q5VZM2, Q63487, Q6NTA4
Gene Symbols: RRAGB
Immunogen: A synthesized peptide derived from human RRAGB(Accession Q5VZM2), corresponding to amino acid residues R79-T129.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
RRAGB
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
RRAGB
Gene Alias:
bA465E19.1, GTP-binding protein ragB, LOC100724885, Rag B, RAGB, Ras related GTP binding B, Ras-related GTP binding B, ras-related GTP-binding protein A, ras-related GTP-binding protein B, ras-related GTP-binding protein B, RGD:619805}, RRAGB, rragB {ECO:0000312
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
10325, 117043, 245670
Content And Storage:
-20°C
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
Q5VZM2, Q63487, Q6NTA4
Gene Symbols:
RRAGB
Immunogen:
A synthesized peptide derived from human RRAGB(Accession Q5VZM2), corresponding to amino acid residues R79-T129.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG