PIPA5106711

MOV10L1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5106711-Each-of-1 In Stock ₹ 44,705.10

PIPA5106711 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

MOV10L1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

MOV10L1

Gene Alias

Cardiac helicase activated by MEF2 protein; cardiac helicase activated by MEF2C protein; cardiac-specific RNA helicase; Champ; Csm; DJ402G11.8; Moloney leukemia virus 10-like 1; moloney leukemia virus 10-like protein 1; Moloney leukemia virus 10-like protein 1 homolog; Mov10 RISC complex RNA helicase like 1; Mov10l1; Mov10l1, Moloney leukemia virus 10-like 1, homolog; Mov10-like 1; MOV10-like protein 1; MOV10-like protein 1 homolog; putative helicase Mov10l1; RNA helicase Mov10l1

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

300141, 54456, 83456

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

Q99MV5, Q9BXT6

Gene Symbols

MOV10L1

Immunogen

A synthesized peptide derived from human MOV10L1(Accession Q9BXT6), corresponding to amino acid residues Q317-L367.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total MOV10L1
  • Isoform 1: ATP-dependent RNA helicase required during spermatogenesis to repress transposable elements and prevent their mobilization, which is essential for germline integrity (PubMed:20534472, PubMed:20547853, PubMed:23166510, PubMed:25762440)
  • Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons (PubMed:20534472, PubMed:20547853, PubMed:23166510, PubMed:25762440)
  • Involved in the primary piRNA metabolic process (PubMed:20534472, PubMed:20547853, PubMed:23166510, PubMed:25762440)
  • Specifically binds to piRNA precursors and promotes the generation of intermediate piRNA processing fragments that are subsequently loaded to Piwi proteins (PubMed:25762440)
  • Acts via its ATP-dependent RNA helicase activity: displays 5'-3' RNA unwinding activity and probably mediates unwinding and funneling of single-stranded piRNA precursor transcripts to the endonuclease that catalyzes the first cleavage step of piRNA processing to generate piRNA intermediate fragments that are subsequently loaded to Piwi proteins (PubMed:25762440)
  • {ECO:0000269; PubMed:20534472, ECO:0000269; PubMed:20547853, ECO:0000269; PubMed:23166510, ECO:0000269; PubMed:25762440}.; Isoform 2: May act downstream of MEF2C during heart formation
  • Acts as a cardiac-specific suppressor of cardiomyocyte hypertrophy and cell cycle progression, suggesting that it may suppress these processes through the regulation of CDKN1A
  • Such results however require additional evidence
  • {ECO:0000305; PubMed:11854500}.

Compare Similar Items

Show Difference

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PIPA5106711

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Antigen:
MOV10L1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MOV10L1

Gene Alias:
Cardiac helicase activated by MEF2 protein; cardiac helicase activated by MEF2C protein; cardiac-specific RNA helicase; Champ; Csm; DJ402G11.8; Moloney leukemia virus 10-like 1; moloney leukemia virus 10-like protein 1; Moloney leukemia virus 10-like protein 1 homolog; Mov10 RISC complex RNA helicase like 1; Mov10l1; Mov10l1, Moloney leukemia virus 10-like 1, homolog; Mov10-like 1; MOV10-like protein 1; MOV10-like protein 1 homolog; putative helicase Mov10l1; RNA helicase Mov10l1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
300141, 54456, 83456

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q99MV5, Q9BXT6

Gene Symbols:
MOV10L1

Immunogen:
A synthesized peptide derived from human MOV10L1(Accession Q9BXT6), corresponding to amino acid residues Q317-L367.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5106712

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Antigen:
PDK1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PDK1

Gene Alias:
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial; [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial; B830012B01; D530020C15Rik; isoenzyme 1; kinase isoenzyme 1; lipoamide; mitochondrial pyruvate dehydrogenase, lipoamide, kinase isoenzyme 1; PDH kinase 1; PDHK1; PDK p48; Pdk1; pyruvate dehydrogenase; pyruvate dehydrogenase kinase 1; Pyruvate dehydrogenase kinase isoform 1; pyruvate dehydrogenase kinase, isoenzyme 1; pyruvate dehydrogenase kinase, isozyme 1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
116551, 228026, 5163

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q15118, Q63065, Q8BFP9

Gene Symbols:
PDK1

Immunogen:
A synthesized peptide derived from human PDK1(Accession Q15118), corresponding to amino acid residues L102-V152.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA5106716

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Antigen:
RRAGB

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RRAGB

Gene Alias:
bA465E19.1, GTP-binding protein ragB, LOC100724885, Rag B, RAGB, Ras related GTP binding B, Ras-related GTP binding B, ras-related GTP-binding protein A, ras-related GTP-binding protein B, ras-related GTP-binding protein B, RGD:619805}, RRAGB, rragB {ECO:0000312

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10325, 117043, 245670

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q5VZM2, Q63487, Q6NTA4

Gene Symbols:
RRAGB

Immunogen:
A synthesized peptide derived from human RRAGB(Accession Q5VZM2), corresponding to amino acid residues R79-T129.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA5106720

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Antigen:
RAB29

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RAB29

Gene Alias:
RAB29; RAB29, member RAS oncogene family; RAB7, member RAS oncogene family-like 1; RAB7L; RAB7L1; Rab-7-like protein 1; Ras-related GTP-binding protein Rab29; ras-related protein Rab-29; Ras-related protein Rab-7L1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
171122, 226422, 8934

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O14966, Q63481, Q91YQ1

Gene Symbols:
RAB29

Immunogen:
A synthesized peptide derived from human RAB29(Accession O14966), corresponding to amino acid residues N114-E164.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG