PIPA5109304
MCU Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5109304-Each-of-1 | In Stock | ₹ 45,646.26 |
PIPA5109304 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,646.26
GST (18%): ₹ 8,216.327
Total Price: ₹ 53,862.587
Antigen
MCU
Classification
Polyclonal
Conjugate
Unconjugated
Gene
MCU
Gene Alias
2010012O16Rik; AV064928; C10orf42; Calcium uniporter protein, mitochondrial; Ccdc109a; coiled-coil domain containing 109A; coiled-coil domain-containing protein 109A; D130073L02Rik; Gm64; HsMCU; MCU; mitochondrial calcium uniporter
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
90550
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles, store in dark
Form
Liquid
Applications
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.
Q8NE86
Gene Symbols
MCU
Immunogen
Recombinant protein within Human MCU aa 51-225
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Positive Control: A549, HL-60, mouse spleen tissue lysates, mouse brain tissue lysates, A431, HT-29, rat cerebellum tissue, human lung cancer tissue, mouse brain tissue, human colon tissue, human esophagus tissue
- Mitochondrial inner membrane calcium uniporter that mediates calcium uptake into mitochondria
- Constitutes the pore-forming and calcium-conducting subunit of the uniporter complex (uniplex)
- Activity is regulated by MICU1 and MICU2
- At low Ca(2+) levels MCU activity is down-regulated by MICU1 and MICU2; at higher Ca(2+) levels MICU1 increases MCU activity
- Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways
- Involved in buffering the amplitude of systolic calcium rises in cardiomyocytes
- While dispensable for baseline homeostatic cardiac function, acts as a key regulator of short-term mitochondrial calcium loading underlying a 'fight-or-flight' response during acute stress: acts by mediating a rapid increase of mitochondrial calcium in pacemaker cells
- participates in mitochondrial permeability transition during ischemia-reperfusion injury
- Regulates glucose-dependent insulin secretion in pancreatic beta-cells by regulating mitochondrial calcium uptake
- Mitochondrial calcium uptake in skeletal muscle cells is involved in muscle size in adults
- Regulates synaptic vesicle endocytosis kinetics in central nerve terminal
- Involved in antigen processing and presentation.
Compare Similar Items
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Antigen: MCU
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MCU
Gene Alias: 2010012O16Rik; AV064928; C10orf42; Calcium uniporter protein, mitochondrial; Ccdc109a; coiled-coil domain containing 109A; coiled-coil domain-containing protein 109A; D130073L02Rik; Gm64; HsMCU; MCU; mitochondrial calcium uniporter
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 90550
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles, store in dark
Form: Liquid
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.: Q8NE86
Gene Symbols: MCU
Immunogen: Recombinant protein within Human MCU aa 51-225
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
MCU
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MCU
Gene Alias:
2010012O16Rik; AV064928; C10orf42; Calcium uniporter protein, mitochondrial; Ccdc109a; coiled-coil domain containing 109A; coiled-coil domain-containing protein 109A; D130073L02Rik; Gm64; HsMCU; MCU; mitochondrial calcium uniporter
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
90550
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles, store in dark
Form:
Liquid
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.:
Q8NE86
Gene Symbols:
MCU
Immunogen:
Recombinant protein within Human MCU aa 51-225
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: gamma-ENaC
Classification: Polyclonal
Conjugate: Unconjugated
Gene: SCNN1G
Gene Alias: [g]ENaC; amiloride sensitive sodium channel gamma1 subunit; amiloride-sensitive epithelial sodium channel gamma subunit; amiloride-sensitive sodium channel gamma-subunit; amiloride-sensitive sodium channel subunit gamma; BESC3; ENaC; ENaC gamma; ENaC gamma subunit; ENaCG; ENaCgamma; epithelial Na(+) channel subunit gamma; epithelial sodium channel gamma subunit; Gamma ENaC; Gamma NaCH; gamma-ENaC; Gamma-NaCH; nonvoltage-gated sodium channel 1 subunit gamma; PHA 1; PHA1; SCNEG; SCNN 1G; Scnn1g; sodium channe epithelial 1 gamma subunit; sodium channel epithelial 1 gamma subunit; Sodium channel nonvoltage-gated 1 gamma (epithelial); sodium channel, non voltage gated 1 gamma subunit; sodium channel, nonvoltage-gated 1 gamma; sodium channel, nonvoltage-gated 1, gamma; Sodium channel, nonvoltage-gated 1, gamma (epithelial); sodium channel, non-voltage-gated 1, gamma subunit; sodium channel, nonvoltage-gated, type I, gamma
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 6340
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles, store in dark
Form: Liquid
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.: P51170
Gene Symbols: SCNN1G
Immunogen: Recombinant protein within Human SCNN1G aa 160-342
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
gamma-ENaC
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
SCNN1G
Gene Alias:
[g]ENaC; amiloride sensitive sodium channel gamma1 subunit; amiloride-sensitive epithelial sodium channel gamma subunit; amiloride-sensitive sodium channel gamma-subunit; amiloride-sensitive sodium channel subunit gamma; BESC3; ENaC; ENaC gamma; ENaC gamma subunit; ENaCG; ENaCgamma; epithelial Na(+) channel subunit gamma; epithelial sodium channel gamma subunit; Gamma ENaC; Gamma NaCH; gamma-ENaC; Gamma-NaCH; nonvoltage-gated sodium channel 1 subunit gamma; PHA 1; PHA1; SCNEG; SCNN 1G; Scnn1g; sodium channe epithelial 1 gamma subunit; sodium channel epithelial 1 gamma subunit; Sodium channel nonvoltage-gated 1 gamma (epithelial); sodium channel, non voltage gated 1 gamma subunit; sodium channel, nonvoltage-gated 1 gamma; sodium channel, nonvoltage-gated 1, gamma; Sodium channel, nonvoltage-gated 1, gamma (epithelial); sodium channel, non-voltage-gated 1, gamma subunit; sodium channel, nonvoltage-gated, type I, gamma
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
6340
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles, store in dark
Form:
Liquid
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.:
P51170
Gene Symbols:
SCNN1G
Immunogen:
Recombinant protein within Human SCNN1G aa 160-342
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: FNDC3A
Classification: Polyclonal
Conjugate: Unconjugated
Gene: FNDC3A
Gene Alias: 1700094E19Rik; bA203I16.1; bA203I16.5; D14Ertd453e; F730017H24Rik; fibronectin domain-containing protein 3a; fibronectin type III domain containing 3a; fibronectin type-III domain-containing protein 3A; FNDC3; fndc3a; HUGO; Human gene expressed in odontoblasts; KIAA0970; sys; wu:fk65b04; zmp:0000001126
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 100333097
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles, store in dark
Form: Liquid
Applications: Immunohistochemistry (Paraffin)
Concentration: 1 mg/mL
Formulation: PBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.: 0
Gene Symbols: FNDC3A
Immunogen: Recombinant protein within zebrafish FNDC3A aa 97-329
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Zebrafish
Product Type: Antibody
Isotype: IgG
Antigen:
FNDC3A
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
FNDC3A
Gene Alias:
1700094E19Rik; bA203I16.1; bA203I16.5; D14Ertd453e; F730017H24Rik; fibronectin domain-containing protein 3a; fibronectin type III domain containing 3a; fibronectin type-III domain-containing protein 3A; FNDC3; fndc3a; HUGO; Human gene expressed in odontoblasts; KIAA0970; sys; wu:fk65b04; zmp:0000001126
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
100333097
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles, store in dark
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin)
Concentration:
1 mg/mL
Formulation:
PBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.:
0
Gene Symbols:
FNDC3A
Immunogen:
Recombinant protein within zebrafish FNDC3A aa 97-329
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Zebrafish
Product Type:
Antibody
Isotype:
IgG
Antigen: Nephrin
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Nphs1
Gene Alias: CNF; Nephrin; nephrin 1; NephrinB; nephrosis 1 homolog, nephrin; nephrosis 1, congenital, Finnish type (nephrin); nephrosis 1, nephrin; NPHN; NPHS1; NPHS1 nephrin; NPHS1, nephrin; renal glomerulus-specific cell adhesion receptor
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 4868
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles, store in dark
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.: O60500
Gene Symbols: Nphs1
Immunogen: Recombinant protein within Human Nephrin aa 1,042-1,241
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
Nephrin
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Nphs1
Gene Alias:
CNF; Nephrin; nephrin 1; NephrinB; nephrosis 1 homolog, nephrin; nephrosis 1, congenital, Finnish type (nephrin); nephrosis 1, nephrin; NPHN; NPHS1; NPHS1 nephrin; NPHS1, nephrin; renal glomerulus-specific cell adhesion receptor
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
4868
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles, store in dark
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.:
O60500
Gene Symbols:
Nphs1
Immunogen:
Recombinant protein within Human Nephrin aa 1,042-1,241
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG