PIPA5110047

ARK5 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA5110047-Each-of-1 In Stock ₹ 44,705.10

PIPA5110047 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

ARK5

Classification

Polyclonal

Conjugate

Unconjugated

Gene

NUAK1

Gene Alias

AMP-activated protein kinase family member 5; AMPK-related protein kinase 5; ARK5; AU014801; AW494241; B230104P22Rik; I79_017442; KIAA0537; NUAK family kinase 1; NUAK family SNF1-like kinase 1; NUAK family, SNF1-like kinase, 1; Nuak1; Omphalocele kinase 1; Omphk1; RGD1309956; ZNUAK family, SNF1-like kinase, 1

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

299694, 9891

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

1.4 mg/mL

Formulation

PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.

O60285

Gene Symbols

NUAK1

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 362-661 of human NUAK1 (NP_055655.1).

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: LERQRSLKKS KKENDFAQSG QDAVPESPSK LSSKRPKGIL KKRSNSEHRS HSTGFIEGVV GPALPSTFKM EQDLCRTGVL LPSSPEAEVP GKLSPKQSAT MPKKGILKKT QQRESGYYSS PERSESSELL DSNDVMGSSI PSPSPPDPAR VTSHSLSCRR KGILKHSSKY SAGTMDPALV SPEMPTLESL SEPGVPAEGL SRSYSRPSSV ISDDSVLSSD SFDLLDLQEN RPARQRIRSC VSAENFLQIQ DFEGLQNRPR PQYLKRYRNR LADSSFSLLT DMDDVTQVYK QALEICSKLN NUAK1 (ARK5) is a serine/threonine kinase that plays a role in many cellular functions
  • The overexpression of this kinase has been associated with tumor invasion and metastasis (colorectal neoplasm)
  • Acts as a regulator of cellular senescence and cellular ploidy by mediating phosphorylation of 'Ser-464' of LATS1, thereby controlling its stability
  • Controls cell adhesion by regulating activity of the myosin protein phosphatase 1 (PP1) complex
  • Acts by mediating phosphorylation of PPP1R12A subunit of myosin PP1: phosphorylated PPP1R12A then interacts with 14-3-3, leading to reduced dephosphorylation of myosin MLC2 by myosin PP1
  • May be involved in DNA damage response: phosphorylates p53/TP53 at 'Ser-15' and 'Ser-392' and is recruited to the CDKN1A/WAF1 promoter to participate in transcription activation by p53/TP53
  • May also act as a tumor malignancy-associated factor by promoting tumor invasion and metastasis under regulation and phosphorylation by AKT1
  • Suppresses Fas-induced apoptosis by mediating phosphorylation of CASP6, thereby suppressing the activation of the caspase and the subsequent cleavage of CFLAR
  • Regulates UV radiation-induced DNA damage response mediated by CDKN1A
  • In association with STK11, phosphorylates CDKN1A in response to UV radiation and contributes to its degradation which is necessary for optimal DNA repair.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA5110047

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Antigen:
ARK5

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NUAK1

Gene Alias:
AMP-activated protein kinase family member 5; AMPK-related protein kinase 5; ARK5; AU014801; AW494241; B230104P22Rik; I79_017442; KIAA0537; NUAK family kinase 1; NUAK family SNF1-like kinase 1; NUAK family, SNF1-like kinase, 1; Nuak1; Omphalocele kinase 1; Omphk1; RGD1309956; ZNUAK family, SNF1-like kinase, 1

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
299694, 9891

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1.4 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.:
O60285

Gene Symbols:
NUAK1

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 362-661 of human NUAK1 (NP_055655.1).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5110048

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Antigen:
NUBP1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NUBP1

Gene Alias:
cytosolic Fe-S cluster assembly factor NUBP1; cytosolic Fe-S cluster assembly factor NUBP1 {ECO:0000255; EMBL:AAH88221.1}; HAMAP-Rule:MF_03038}; NBP; NBP 1; NBP 1 {ECO:0000255; NBP1; NBP35; NUBP1; nubp1 {ECO:0000312; nucleotide binding protein (e.coli MinD like); nucleotide binding protein 1; nucleotide binding protein 1 (E.coli MinD like); nucleotide binding protein 1 (MinD homolog, E. coli); nucleotide-binding protein 1; nucleotide-binding protein 1 {ECO:0000255

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
26425, 287042, 4682

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.91 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.:
P53384, Q5I0L4, Q9R060

Gene Symbols:
NUBP1

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 201-320 of human NUBP1 (NP_002475.2).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5110049

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Antigen:
NUDT16

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NUDT16

Gene Alias:
2310041H06Rik; 2810047L04Rik; 2900006H04Rik; AI851783; IDP phosphatase; IDPase; inosine diphosphate phosphatase; LOC100718706; m7GpppN-mRNA hydrolase; nucleoside diphosphate-linked moiety X motif 16; nudix; nudix (nucleoside diphosphate linked moiety X)-type motif 16; nudix hydrolase 16; Nudix motif 16; nudix-type motif 16; NUDT16; RGD1311387; testicular tissue protein Li 129; U8 snoRNA-binding protein H29K; U8 snoRNA-decapping enzyme

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
131870, 75686

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1.56 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.:
Q6P3D0, Q96DE0

Gene Symbols:
NUDT16

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 60-130 of human NUDT16 (NP_689608.2).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5110050

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Antigen:
NUFIP2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Nufip2

Gene Alias:
1110001M19Rik; 182-FIP; 82 kDa FMRP-interacting protein; 82-FIP; 82-kD FMRP Interacting Protein; 9530056D24Rik; AI256692; AI461731; Cell proliferation-inducing gene 1 protein; FIP-82; FMRP-interacting protein 2; Fragile X Mental Retardation Protein; im:7136583; KIAA1321; LOW QUALITY PROTEIN: nuclear fragile X mental retardation-interacting protein 2; mKIAA1321; nuclear FMR1 interacting protein 2; nuclear FMR1 interacting protein 2; nuclear fragile X mental retardation-interacting protein 2; nuclear fragile X mental retardation protein interacting protein 2; nuclear fragile X mental retardation-interacting protein 2; NUFIP2; NUFIP2, FMR1 interacting protein 2; PIG1; proliferation-inducing gene 1

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
57532, 681371, 68564

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
3.76 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.:
Q5F2E7, Q7Z417

Gene Symbols:
Nufip2

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 456-695 of human NUFIP2 (NP_065823.1).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG