PIPA5114554

Phospho-BID (Ser78) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA5114554-Each-of-1 In Stock ₹ 44,705.10

PIPA5114554 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

Phospho-BID (Ser78)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

BID

Gene Alias

2700049M22Rik; AI875481; apoptic d; apoptic death agonist; apoptotic death agonist BID; AU022477; BH3 interacting domain death agonist; BH3-interacting domain death agonist; BH3-interacting domain death agonist p11; BH3-interacting domain death agonist p13; BH3-interacting domain death agonist p15; Bid; BID isoform ES(1b); BID isoform L(2); BID isoform Si6; desmocollin type 4; FP497; HGNC:1050; Human BID coding sequence; MGC15319; MGC42355; OTTHUMP00000196197; p11 BID; p13 BID; p15 BID; p22 BID

Host Species

Rabbit

Purification Method

sequential chromatography

Regulatory Status

RUO

Gene ID (Entrez)

637, 64625

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.

P55957, Q9JLT6

Gene Symbols

BID

Immunogen

A synthesized peptide derived from human BID around the phosphorylation site of Ser78.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of BID only when phosphorylated at Ser78
  • BID is a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2
  • Bid is a member of the BCL-2 family of cell death regulators
  • BID is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release
  • BID is also a pro-apoptotic member of the Bcl 2 family
  • BID usually exists in an inactive form in the cytosolic fraction of living cells and becomes cleaved and activated by caspase 8 in response to TNF alpha or Fas ligand
  • Once BID is cleaved, the C-terminal 15 kDa fragment of BID (p15) translocates onto mitochondria and is sufficient to trigger cytochrome c release, resulting in cell apoptosis
  • BID serves as a direct molecular link between caspase 8 activation and mitochondrial death machinery.

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Thermo Scientific

PIPA5114554

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Antigen:
Phospho-BID (Ser78)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
BID

Gene Alias:
2700049M22Rik; AI875481; apoptic d; apoptic death agonist; apoptotic death agonist BID; AU022477; BH3 interacting domain death agonist; BH3-interacting domain death agonist; BH3-interacting domain death agonist p11; BH3-interacting domain death agonist p13; BH3-interacting domain death agonist p15; Bid; BID isoform ES(1b); BID isoform L(2); BID isoform Si6; desmocollin type 4; FP497; HGNC:1050; Human BID coding sequence; MGC15319; MGC42355; OTTHUMP00000196197; p11 BID; p13 BID; p15 BID; p22 BID

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
637, 64625

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P55957, Q9JLT6

Gene Symbols:
BID

Immunogen:
A synthesized peptide derived from human BID around the phosphorylation site of Ser78.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5114555

--


Antigen:
Phospho-c-Abl (Tyr226)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ABL1

Gene Alias:
Abelson murine leukemia oncogene; Abelson murine leukemia viral (v-abl) oncogene homolog 1; abelson murine leukemia viral oncogene homolog 1; Abelson tyrosine-protein kinase 1; Abl; Abl 1 antib; ABL proto-oncogene 1, non-receptor tyrosine kinase; Abl1; ABL2; ABLL; AI325092; ARG; B30; bcr/abl; bcr/c-abl oncogene protein; c-ABL; c-abl oncogene 1, non-receptor tyrosine kinase; c-abl oncogene 1, receptor tyrosine kinase; c-ABL1; E430008G22Rik; JTK7; p150; Proto-oncogene c-Abl; proto-oncogene tyrosine-protein kinase ABL1; RP11-83J21.1; Tyrosine kinase ARG; tyrosine-protein kinase ABL1; v-abl; v-abl Abelson murine leukemia oncogene 1; v-abl Abelson murine leukemia viral oncogene 1; v-abl Abelson murine leukemia viral oncogene homolog 1

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11350, 25, 311860

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P00519, P00520

Gene Symbols:
ABL1

Immunogen:
A synthesized peptide derived from human ABL1(Accession P00519), corresponding to amino acid residues around phosphorylated Tyr226.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5114556

--


Antigen:
Phospho-Caspase 8 (Tyr380)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Casp8

Gene Alias:
ALPS2B; apoptosis-related cysteine peptidase; apoptotic cysteine protease; Apoptotic protease Mch-5; CAP4; CASP8; CASP-8; caspase 8; caspase 8, apoptosis-related cysteine peptidase; caspase 8, apoptosis-related cysteine protease; Caspase8; caspase-8; Caspase-8 precursor; Caspase-8 subunit p10; Caspase-8 subunit p18; EC 3.4.22.61; FADD-homologous ICE/ced-3-like protease; FADD-like ICE; Fas-linked ICE-like protease; FLICE; FLJ17672; ICE8; ICE-like apoptotic protease 5; MACH; MACH-alpha-1/2/3 protein; MACH-beta-1/2/3/4 protein; MCH5; MGC78473; MORT1-associated ced-3 homolog; OTTHUMP00000163720; OTTHUMP00000165063; OTTHUMP00000206557; OTTHUMP00000206581

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12370, 64044, 841

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.:
O89110, Q14790, Q9JHX4

Gene Symbols:
Casp8

Immunogen:
A synthesized peptide derived from human Caspase 8 around the phosphorylation site of Tyr380.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5114557

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Antigen:
Phospho-Caspase 9 (Ser196)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CASP9

Gene Alias:
25 kDa caspase-9 dominant negative protein; AI115399; APAF3; APAF-3; apoptotic protease activating factor 3; apoptotic protease MCH-6; Apoptotic protease-activating factor 3; AW493809; cas9; CASP 9; CASP9; CASP-9; Casp9_v1; Casp-9-CTD; caspase 9; caspase 9, apoptosis-related cysteine peptidase; caspase 9, apoptosis-related cysteine protease; Caspase9; caspase-9; caspase-9 dominant negative form; Caspase-9 precursor; Caspase-9 subunit p10; Caspase-9 subunit p35; CASPASE-9c; caspase-9-carboxyl-terminal divergent; CTD; Ice-Lap6; ICE-like apoptotic protease 6; Mch6; OTTHUMP00000002324; PPP1R56; protein phosphatase 1, regulatory subunit 56; RNCASP9; RP11-265F14.3

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12371, 842

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P55211, Q8C3Q9

Gene Symbols:
CASP9

Immunogen:
A synthesized peptide derived from human Caspase 9 around the phosphorylation site of Ser196.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG