PIPA5114560
Phospho-CDK4 (Thr172) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5114560-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA5114560 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
Phospho-CDK4 (Thr172)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Cdk4
Gene Alias
Cdk4; Cell division protein kinase 4; CMM3; Crk3; cyclin dependent kinase 4; cyclin-dependent kinase 4; MGC14458; p34<PSK-J3>/cdk4; PSK-J3; serine/threonine kinase; Unknown (protein for MGC:133903)
Host Species
Rabbit
Purification Method
sequential chromatography
Regulatory Status
RUO
Gene ID (Entrez)
1019, 12567, 94201
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.
P11802, P30285, P35426
Gene Symbols
Cdk4
Immunogen
A synthesized peptide derived from human CDK4(Accession P11802), corresponding to amino acid residues around phosphorylated Thr172.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of CDK4 only when phosphorylated at Thr172
- CDK4/cyclin D3 serine/threonine kinase is dimeric protein complex
- CDK4 is a member of the cyclin-dependent protein kinase family and is involved in the control of cell proliferation during the G1 phase of cell cycle
- CDK4 forms a complex with the D-type cyclins and is inhibited by p16 (cyclin-dependent kinase inhibitor-2)
- CDK4 can mediate phosphorylation of the C-terminal region of Rb protein leading to an active transcriptional repression of E2F complex
- CDC37 and HSP90 can preferentially associate with the fraction of CDK4 not bound to D-type cyclins
- SMAD3 is a major physiologic substrate of the G1 cyclin-dependent kinases CDK4 and CDK2
- Although CDK6 and CDK4 can both phosphorylate multiple residues in the Rb protein, they do so with different residue selectivity in vitro; CDK6 phosphorylates Thr821 while CDK4 phosphorylates Thr826 on Rb protein.
Compare Similar Items
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Antigen: Phospho-CDK4 (Thr172)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Cdk4
Gene Alias: Cdk4; Cell division protein kinase 4; CMM3; Crk3; cyclin dependent kinase 4; cyclin-dependent kinase 4; MGC14458; p34<PSK-J3>/cdk4; PSK-J3; serine/threonine kinase; Unknown (protein for MGC:133903)
Host Species: Rabbit
Purification Method: sequential chromatography
Regulatory Status: RUO
Gene ID (Entrez): 1019, 12567, 94201
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.: P11802, P30285, P35426
Gene Symbols: Cdk4
Immunogen: A synthesized peptide derived from human CDK4(Accession P11802), corresponding to amino acid residues around phosphorylated Thr172.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-CDK4 (Thr172)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Cdk4
Gene Alias:
Cdk4; Cell division protein kinase 4; CMM3; Crk3; cyclin dependent kinase 4; cyclin-dependent kinase 4; MGC14458; p34<PSK-J3>/cdk4; PSK-J3; serine/threonine kinase; Unknown (protein for MGC:133903)
Host Species:
Rabbit
Purification Method:
sequential chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
1019, 12567, 94201
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P11802, P30285, P35426
Gene Symbols:
Cdk4
Immunogen:
A synthesized peptide derived from human CDK4(Accession P11802), corresponding to amino acid residues around phosphorylated Thr172.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-C-Jun (Ser73)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: JUN
Gene Alias: Activator protein 1, AH119, AP1, AP-1, Avian sarcoma virus 17 (v-jun) oncogene homolog, cjun, c-Jun, c-jun transcription factor, enhancer-binding protein AP1, I79_009953, immediate early, JUN, Jun A, Jun activation domain binding protein, Jun oncogene, jun proto-oncogene, Jun proto-oncogene, AP-1 transcription factor subunit, Junc, JUND, p39, proto-oncogene c-Jun, Rjg-9, transcription factor, transcription factor AP-1, V-jun avian sarcoma virus 17 oncogene homolog, v-jun sarcoma virus 17 oncogene homolog
Host Species: Rabbit
Purification Method: sequential chromatography
Regulatory Status: RUO
Gene ID (Entrez): 16476, 24516, 335916, 3725
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.: P05412, P05627, P17325
Gene Symbols: JUN
Immunogen: A synthesized peptide derived from human JUN(Accession P05412), corresponding to amino acid residues around phosphorylated Ser73.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat, Zebrafish
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-C-Jun (Ser73)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
JUN
Gene Alias:
Activator protein 1, AH119, AP1, AP-1, Avian sarcoma virus 17 (v-jun) oncogene homolog, cjun, c-Jun, c-jun transcription factor, enhancer-binding protein AP1, I79_009953, immediate early, JUN, Jun A, Jun activation domain binding protein, Jun oncogene, jun proto-oncogene, Jun proto-oncogene, AP-1 transcription factor subunit, Junc, JUND, p39, proto-oncogene c-Jun, Rjg-9, transcription factor, transcription factor AP-1, V-jun avian sarcoma virus 17 oncogene homolog, v-jun sarcoma virus 17 oncogene homolog
Host Species:
Rabbit
Purification Method:
sequential chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
16476, 24516, 335916, 3725
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P05412, P05627, P17325
Gene Symbols:
JUN
Immunogen:
A synthesized peptide derived from human JUN(Accession P05412), corresponding to amino acid residues around phosphorylated Ser73.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat, Zebrafish
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-COX4 (Ser58)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: COX4I1
Gene Alias: AL024441; C16orf2; C16orf4; COX; cox iv; COX IV-1; Cox IV-2; Cox4; COX4 neighbor; Cox4-1; COX4-2; Cox4a; COX4AL; Cox4b; COX4I1; cox4i1.S; Cox4i2; COX4L2; COX4NB; coxiv; COXIV-1; CoxIV-2; cytochrome c oxidase polypeptide IV; Cytochrome c oxidase subunit 4 isoform 1, mitochondrial; cytochrome c oxidase subunit 4 isoform 2, mitochondrial; cytochrome c oxidase subunit 4I1; cytochrome c oxidase subunit 4I2; cytochrome c oxidase subunit IV; cytochrome c oxidase subunit IV isoform 1; cytochrome c oxidase subunit IV isoform 1 precursor; cytochrome c oxidase subunit IV isoform 1 S homeolog; cytochrome c oxidase subunit IV isoform 2; cytochrome c oxidase subunit IV isoform 2 (lung); cytochrome c oxidase subunit IV precursor EC 1.9.3.1; cytochrome c oxidase subunit IV-like 2; cytochrome c oxidase, subunit 4a; cytochrome c oxidase, subunit 4b; cytochrome c oxidase, subunit IV; cytochrome c oxidase, subunit IVa; cytochrome c oxidase, subunit IVb; cytochrome c oxydase subunit 4; dJ857M17.2; EMC8; ER
Host Species: Rabbit
Purification Method: sequential chromatography
Regulatory Status: RUO
Gene ID (Entrez): 12857, 1327, 29445
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.: P10888, P13073, P19783
Gene Symbols: COX4I1
Immunogen: A synthesized peptide derived from human COX IV around the phosphorylation site of Ser58.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-COX4 (Ser58)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
COX4I1
Gene Alias:
AL024441; C16orf2; C16orf4; COX; cox iv; COX IV-1; Cox IV-2; Cox4; COX4 neighbor; Cox4-1; COX4-2; Cox4a; COX4AL; Cox4b; COX4I1; cox4i1.S; Cox4i2; COX4L2; COX4NB; coxiv; COXIV-1; CoxIV-2; cytochrome c oxidase polypeptide IV; Cytochrome c oxidase subunit 4 isoform 1, mitochondrial; cytochrome c oxidase subunit 4 isoform 2, mitochondrial; cytochrome c oxidase subunit 4I1; cytochrome c oxidase subunit 4I2; cytochrome c oxidase subunit IV; cytochrome c oxidase subunit IV isoform 1; cytochrome c oxidase subunit IV isoform 1 precursor; cytochrome c oxidase subunit IV isoform 1 S homeolog; cytochrome c oxidase subunit IV isoform 2; cytochrome c oxidase subunit IV isoform 2 (lung); cytochrome c oxidase subunit IV precursor EC 1.9.3.1; cytochrome c oxidase subunit IV-like 2; cytochrome c oxidase, subunit 4a; cytochrome c oxidase, subunit 4b; cytochrome c oxidase, subunit IV; cytochrome c oxidase, subunit IVa; cytochrome c oxidase, subunit IVb; cytochrome c oxydase subunit 4; dJ857M17.2; EMC8; ER
Host Species:
Rabbit
Purification Method:
sequential chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
12857, 1327, 29445
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P10888, P13073, P19783
Gene Symbols:
COX4I1
Immunogen:
A synthesized peptide derived from human COX IV around the phosphorylation site of Ser58.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-Cytokeratin 18 (Ser51)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: KRT18
Gene Alias: cb83; Cell proliferation-inducing gene 46 protein; CK 18; CK18; CK-18; CYK18; cytokeratin 18; cytokeratin endo B; cytokeratin type -1; DAPK-1; Cytokeratin18; cytokeratin-18; dapk1; dorsal aorta proneprin kinesin-1; DreK18; Endo B; I79_023185; K 18; K18; keratin 18; keratin 18, type I; keratin 18a, tandem duplicate 1; keratin complex 1, acidic, gene 18; keratin D; Keratin, type I cytoskeletal 18; Keratin18; keratin-18; Kerd; KRT 18; Krt1-18; KRT18; krt18 {ECO:0000250; krt18a.1; LOC100008885; PIG46; sb:cb83; type I cytoskeletal 18; UniProtKB:P05783}; wu:fa13f02; wu:fb36b04
Host Species: Rabbit
Purification Method: sequential chromatography
Regulatory Status: RUO
Gene ID (Entrez): 16668, 3875
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.: P05783, P05784
Gene Symbols: KRT18
Immunogen: A synthesized peptide derived from human Cytokeratin 18 around the phosphorylation site of Ser51.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-Cytokeratin 18 (Ser51)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
KRT18
Gene Alias:
cb83; Cell proliferation-inducing gene 46 protein; CK 18; CK18; CK-18; CYK18; cytokeratin 18; cytokeratin endo B; cytokeratin type -1; DAPK-1; Cytokeratin18; cytokeratin-18; dapk1; dorsal aorta proneprin kinesin-1; DreK18; Endo B; I79_023185; K 18; K18; keratin 18; keratin 18, type I; keratin 18a, tandem duplicate 1; keratin complex 1, acidic, gene 18; keratin D; Keratin, type I cytoskeletal 18; Keratin18; keratin-18; Kerd; KRT 18; Krt1-18; KRT18; krt18 {ECO:0000250; krt18a.1; LOC100008885; PIG46; sb:cb83; type I cytoskeletal 18; UniProtKB:P05783}; wu:fa13f02; wu:fb36b04
Host Species:
Rabbit
Purification Method:
sequential chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
16668, 3875
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P05783, P05784
Gene Symbols:
KRT18
Immunogen:
A synthesized peptide derived from human Cytokeratin 18 around the phosphorylation site of Ser51.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG