PIPA5114594

Phospho-JAK2 (Tyr1008) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5114594-Each-of-1 In Stock ₹ 44,705.10

PIPA5114594 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

Phospho-JAK2 (Tyr1008)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

JAK2

Gene Alias

EC 2.7.10.2; Fd17; JAK 2; JAK2; JAK-2; Janus kinase 2; Janus kinase 2 (a protein tyrosine kinase); JTK 10; JTK10; kinase Jak2; THCYT3; Tyrosine-protein kinase JAK2

Host Species

Rabbit

Purification Method

sequential chromatography

Regulatory Status

RUO

Gene ID (Entrez)

16452, 24514, 3717

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.

O60674, Q62120, Q62689

Gene Symbols

JAK2

Immunogen

A synthesized peptide derived from human Jak2 around the phosphorylation site of Tyr1008.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of Jak2 only when phosphorylated at Tyr1008
  • Janus kinase 2 (JAK2) is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways and is mutated in polycythemia vera
  • This kinase contains the catalytic domain (JH1) of JAK2
  • The activation of JAKs can lead to the phosphorylation of STAT (signal transducers and activatiors of transcription) proteins, which dimerize and translocate to the nucleus
  • Once translocated to the nucleus, the STAT proteins can modify transcription of numerous genes, including interferon-stimulated genes
  • JAK2 is required for the IFN gamma-receptor complex initiation and JAK1 functions as an amplifier
  • Some studies have suggested that the role of JAK2 might be performed by Tyk2 and JAK3, if they were positioned correctly within the IFN gamma-receptor complex
  • Mutations affecting JAK2 can cause Budd-Chiari syndrome, Polycythemia vera, Thrombocythemia 3, myelofibrosis, or Acute myelogenous leukemia.

Compare Similar Items

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Img

Thermo Scientific

PIPA5114594

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Antigen:
Phospho-JAK2 (Tyr1008)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
JAK2

Gene Alias:
EC 2.7.10.2; Fd17; JAK 2; JAK2; JAK-2; Janus kinase 2; Janus kinase 2 (a protein tyrosine kinase); JTK 10; JTK10; kinase Jak2; THCYT3; Tyrosine-protein kinase JAK2

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16452, 24514, 3717

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.:
O60674, Q62120, Q62689

Gene Symbols:
JAK2

Immunogen:
A synthesized peptide derived from human Jak2 around the phosphorylation site of Tyr1008.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5114595

--


Antigen:
Phospho-JIP1 (Thr205)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MAPK8IP1

Gene Alias:
C-Jun-amino-terminal kinase-interacting protein 1; Ib1; IB-1; Islet-brain 1; islet-brain-1; JIP1; JIP-1; JIP-1-related protein; JNK MAP kinase scaffold protein 1; JNK-interacting protein 1; JRP; Mapk8ip; Mapk8ip1; mitogen activated protein kinase 8 interacting protein; mitogen activated protein kinase 8 interacting protein 1; mitogen-activated protein kinase 8 interacting protein 1; mitogen-activated protein kinase 8-interacting protein 1; mjip-2a; PRKM8 interacting protein; PRKM8IP; protein kinase, mitogen-activated 8 interacting protein; Skip

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
116457, 19099, 9479

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q9R237, Q9UQF2, Q9WVI9

Gene Symbols:
MAPK8IP1

Immunogen:
A synthesized peptide derived from human JIP1 around the phosphorylation site of Thr205.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5114596

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Antigen:
Phospho-Lamin A/C (Ser390)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
LMNA

Gene Alias:
70 kDa lamin; cb948; CDCD1; CDDC; CMD1A; CMT2B1; Dhe; EMD2; FPL; FPLD; FPLD2; HGPS; I79_009616; IDC; lamin; lamin A; lamin A/C; lamin A/C L homeolog; lamin A/C-like 1; Lamin A+C mutant; Lamin AC; lamin a-c; lamin C; lamin C2; lamin-A; Lamin-A/C; LDP1; LFP; LGMD1B; LMN1; lmna; LMNA protein; lmna.L; lmna-A; LMNC; LMNL1; mutant 453W; Mutant lamin A/C; nuclear intermediate filament protein; nuclear lamin A; prelamin-A/C; PRO1; progerin mutant; Renal carcinoma antigen NY-REN-32; RP11-54H19.1; unnamed protein product; wu:fk66d12; XELAEV_18040808mg

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16905, 4000, 60374

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P02545, P48678, P48679

Gene Symbols:
LMNA

Immunogen:
A synthesized peptide derived from human Lamin A/C around the phosphorylation site of Ser390.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5114597

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Antigen:
Phospho-LETM1 (Thr192)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
LETM1

Gene Alias:
LETM1; LETM1 and EF-hand domain-containing protein 1, mitochondrial; leucine zipper and EF-hand containing transmembrane protein 1; leucine zipper-EF-hand containing transmembrane protein 1; leucine zipper-EF-hand-containing transmembrane protein 1; Mdm38 homolog; Mitochondrial proton/calcium exchanger protein

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3954, 56384

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.:
O95202, Q9Z2I0

Gene Symbols:
LETM1

Immunogen:
A synthesized peptide derived from human LETM1 around the phosphorylation site of Thr192.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG