PIPA5117229

Phospho-JAK2 (Tyr1007, Tyr1008) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5117229-Each-of-1 In Stock ₹ 45,560.70

PIPA5117229 - Each of 1

₹ 45,560.70

In Stock

Quantity

1

Base Price: ₹ 45,560.70

GST (18%): ₹ 8,200.926

Total Price: ₹ 53,761.626

Antigen

Phospho-JAK2 (Tyr1007, Tyr1008)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

JAK2

Gene Alias

EC 2.7.10.2; Fd17; JAK 2; JAK2; JAK-2; Janus kinase 2; Janus kinase 2 (a protein tyrosine kinase); JTK 10; JTK10; kinase Jak2; THCYT3; Tyrosine-protein kinase JAK2

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

16452, 3717

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

2.48 mg/mL

Formulation

PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3

Gene Accession No.

O60674, Q62120

Gene Symbols

JAK2

Immunogen

A synthetic phosphorylated peptide around Y1007 of human JAK2 (NP_0049631)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Positive Samples: NIH/3T3 Immunogen sequence: KEYYK Janus kinase 2 (JAK2) is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways and is mutated in polycythemia vera
  • This kinase contains the catalytic domain (JH1) of JAK2
  • The activation of JAKs can lead to the phosphorylation of STAT (signal transducers and activatiors of transcription) proteins, which dimerize and translocate to the nucleus
  • Once translocated to the nucleus, the STAT proteins can modify transcription of numerous genes, including interferon-stimulated genes
  • JAK2 is required for the IFN gamma-receptor complex initiation and JAK1 functions as an amplifier
  • Some studies have suggested that the role of JAK2 might be performed by Tyk2 and JAK3, if they were positioned correctly within the IFN gamma-receptor complex
  • Mutations affecting JAK2 can cause Budd-Chiari syndrome, Polycythemia vera, Thrombocythemia 3, myelofibrosis, or Acute myelogenous leukemia.

Compare Similar Items

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Thermo Scientific

PIPA5117229

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Antigen:
Phospho-JAK2 (Tyr1007, Tyr1008)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
JAK2

Gene Alias:
EC 2.7.10.2; Fd17; JAK 2; JAK2; JAK-2; Janus kinase 2; Janus kinase 2 (a protein tyrosine kinase); JTK 10; JTK10; kinase Jak2; THCYT3; Tyrosine-protein kinase JAK2

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16452, 3717

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
2.48 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3

Gene Accession No.:
O60674, Q62120

Gene Symbols:
JAK2

Immunogen:
A synthetic phosphorylated peptide around Y1007 of human JAK2 (NP_0049631)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA511723

--


Antigen:
PDGF-B

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PDGFB

Gene Alias:
becaplermin; c-sis; I79_017626; IBGC5; PDGF; pdgf protein; PDGF subunit B; PDGF, B chain; PDGF2; PDGF-2; Pdgfb; PDGF-B; platelet derived growth factor subunit B; platelet derived growth factor, B polypeptide; platelet-derived growth factor 2; platelet-derived growth factor B; platelet-derived growth factor B chain; platelet-derived growth factor B subunit; platelet-derived growth factor beta; platelet-derived growth factor beta isoform 1, preproprotein; platelet-derived growth factor beta polypeptide; platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog); Platelet-derived growth factor subunit B; platelet-derived growth factor, beta polypeptide (oncogene SIS); Platelet-derived growth factor, same as Sis (Simian sarcoma viral oncogene homologue, c-sis); proto-oncogene c-Sis; Sis; SSV; v-sis platelet-derived growth factor beta polypeptide (simian sarcoma viral oncogene homolog)

Host Species:
Rabbit

Purification Method:
Ammonium sulfate precipitation, Size-exclusion - Dialysis

Regulatory Status:
RUO

Gene ID (Entrez):
5155

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
2 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
P01127

Gene Symbols:
PDGFB

Immunogen:
KLH conjugated synthetic peptide between 212-241 amino acids from the C-terminal region of human PDGFB

Quantity:
400 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA5117230

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Antigen:
Phospho-Tau (Thr231)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MAPT

Gene Alias:
AI413597; AW045860; DDPAC; FLJ31424; FTDP17; FTDP-17; G protein beta1/gamma2 subunit-interacting factor 1; map tau; Mapt; MAPTL; MGC138549; microtubule associated protein tau; microtubule-associated protein tau; microtubule-associated protein tau, isoform 4; microtubules; MSTD; Mtapt; MTBT1; MTBT2; Neurofibrillary tangle protein; neurofibrillary tangles; Neuronal Marker; paired helical filament-tau; PHFtau; PHF-tau; PPND; PPP1R103; protein phosphatase 1, regulatory subunit 103; pTau; RNPTAU; Tau; Tau microtubule-associated protein; tau protein; Tau-4; Tau5; Unknown (protein for MGC:134287)

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
17762

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1.56 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.:
P10637

Gene Symbols:
MAPT

Immunogen:
A synthetic phosphorylated peptide around T548 of human Tau (NP_0585193?)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG

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PIPA5117233

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Antigen:
Phospho-Aurora A/B/C (Thr288, Thr232, Thr198)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Aurka

Gene Alias:
Aik; Aik2; AIM1; AIM-1; Airk; AIRK1; AIRK2; AL022959; ARK1; ARK-1; ARK2; ARK-2; AU019385; AURA; AurB; AURKA; AURKB; aurkb-sv1; aurkb-sv2; Aurora 1; aurora 2; aurora A; aurora- and Ipl1-like midbody-associated protein 1; aurora B; aurora family kinase 1; Aurora kinase A; aurora kinase B; aurora kinase B-Sv1; aurora kinase B-Sv2; aurora/IPL1-like kinase; aurora/IPL1-related kinase 1; Aurora/IPL1-related kinase 2; aurora-1; aurora-A; aurora-B; aurora-related kinase 1; aurora-related kinase 2; AW539821; Ayk1; Breast tumor-amplified kinase; Btak; IAK; IAK1; IPL1; ipl1- and aurora-related kinase 1; PPP1R47; PPP1R48; protein phosphatase 1, regulatory subunit 47; protein phosphatase 1, regulatory subunit 48; ratAurA; serine/threonine kinase 12; serine/threonine kinase 5; serine/threonine kinase 6; serine/threonine protein kinase 15; serine/threonine protein kinase 6; serine/threonine-protein kinase 12; Serine/threonine-protein kinase 15; Serine/threonine-protein kinase 5; serine/threonine-prot

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
114592, 261730, 292554, 6790, 6795, 9212

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
2.33 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.:
O14965, O55099, P59241, Q96GD4, Q9UQB9

Gene Symbols:
Aurka, Aurkb, AURKC

Immunogen:
A synthetic phosphorylated peptide around T288 of human AURKA/AURKB/AURKCAURKA (NP_0035912)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG