PIPA5117230

Phospho-Tau (Thr231) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA5117230-Each-of-1 In Stock ₹ 45,560.70

PIPA5117230 - Each of 1

₹ 45,560.70

In Stock

Quantity

1

Base Price: ₹ 45,560.70

GST (18%): ₹ 8,200.926

Total Price: ₹ 53,761.626

Antigen

Phospho-Tau (Thr231)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

MAPT

Gene Alias

AI413597; AW045860; DDPAC; FLJ31424; FTDP17; FTDP-17; G protein beta1/gamma2 subunit-interacting factor 1; map tau; Mapt; MAPTL; MGC138549; microtubule associated protein tau; microtubule-associated protein tau; microtubule-associated protein tau, isoform 4; microtubules; MSTD; Mtapt; MTBT1; MTBT2; Neurofibrillary tangle protein; neurofibrillary tangles; Neuronal Marker; paired helical filament-tau; PHFtau; PHF-tau; PPND; PPP1R103; protein phosphatase 1, regulatory subunit 103; pTau; RNPTAU; Tau; Tau microtubule-associated protein; tau protein; Tau-4; Tau5; Unknown (protein for MGC:134287)

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

17762

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

1.56 mg/mL

Formulation

PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.

P10637

Gene Symbols

MAPT

Immunogen

A synthetic phosphorylated peptide around T548 of human Tau (NP_0585193?)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Positive Samples: Mouse brain Immunogen sequence: VRTPP Tau is a neuronal microtubule-associated protein found predominantly on axons
  • The function of Tau is to promote tubulin polymerization and stabilize microtubules
  • The C-terminus binds axonal microtubules while the N- terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both
  • Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome
  • The short isoforms allow plasticity of the cytoskeleton while the longer isoforms may preferentially play a role in its stabilization
  • In its hyper-phosphorylated form, Tau is the major component of paired helical filaments (PHF), the building block of neurofibrillary lesions in Alzheimer's diseases (AD) brain
  • Hyper-phosphorylation impairs the microtubule binding function of Tau, resulting in the destabilization of microtubules in AD brains, μgtimately leading to the degeneration of the affected neurons
  • Numerous serine/threonine kinases phosphorylate Tau, including GSK-3beta, protein kinase A (PKA), cyclin-dependent kinase 5 (cdk5) and casein kinase II
  • Hyper-phosphorylated Tau is found in neurofibrillary lesions in a range and other central nervous system disorders such as Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA5117230

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Antigen:
Phospho-Tau (Thr231)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MAPT

Gene Alias:
AI413597; AW045860; DDPAC; FLJ31424; FTDP17; FTDP-17; G protein beta1/gamma2 subunit-interacting factor 1; map tau; Mapt; MAPTL; MGC138549; microtubule associated protein tau; microtubule-associated protein tau; microtubule-associated protein tau, isoform 4; microtubules; MSTD; Mtapt; MTBT1; MTBT2; Neurofibrillary tangle protein; neurofibrillary tangles; Neuronal Marker; paired helical filament-tau; PHFtau; PHF-tau; PPND; PPP1R103; protein phosphatase 1, regulatory subunit 103; pTau; RNPTAU; Tau; Tau microtubule-associated protein; tau protein; Tau-4; Tau5; Unknown (protein for MGC:134287)

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
17762

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1.56 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.:
P10637

Gene Symbols:
MAPT

Immunogen:
A synthetic phosphorylated peptide around T548 of human Tau (NP_0585193?)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG

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PIPA5117233

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Antigen:
Phospho-Aurora A/B/C (Thr288, Thr232, Thr198)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Aurka

Gene Alias:
Aik; Aik2; AIM1; AIM-1; Airk; AIRK1; AIRK2; AL022959; ARK1; ARK-1; ARK2; ARK-2; AU019385; AURA; AurB; AURKA; AURKB; aurkb-sv1; aurkb-sv2; Aurora 1; aurora 2; aurora A; aurora- and Ipl1-like midbody-associated protein 1; aurora B; aurora family kinase 1; Aurora kinase A; aurora kinase B; aurora kinase B-Sv1; aurora kinase B-Sv2; aurora/IPL1-like kinase; aurora/IPL1-related kinase 1; Aurora/IPL1-related kinase 2; aurora-1; aurora-A; aurora-B; aurora-related kinase 1; aurora-related kinase 2; AW539821; Ayk1; Breast tumor-amplified kinase; Btak; IAK; IAK1; IPL1; ipl1- and aurora-related kinase 1; PPP1R47; PPP1R48; protein phosphatase 1, regulatory subunit 47; protein phosphatase 1, regulatory subunit 48; ratAurA; serine/threonine kinase 12; serine/threonine kinase 5; serine/threonine kinase 6; serine/threonine protein kinase 15; serine/threonine protein kinase 6; serine/threonine-protein kinase 12; Serine/threonine-protein kinase 15; Serine/threonine-protein kinase 5; serine/threonine-prot

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
114592, 261730, 292554, 6790, 6795, 9212

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
2.33 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.:
O14965, O55099, P59241, Q96GD4, Q9UQB9

Gene Symbols:
Aurka, Aurkb, AURKC

Immunogen:
A synthetic phosphorylated peptide around T288 of human AURKA/AURKB/AURKCAURKA (NP_0035912)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5117235

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Antigen:
Phospho-p53 (Ser6)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Tp53

Gene Alias:
Antigen NY-CO-13; bbl; BCC7; bfy; bhy; cellular tumor antigen p53; Cys 51 Stop; EGK_08142; FLJ92943; HGNC11998; I79_002739; LFS1; Li-Fraumeni syndrome; mutant p53; mutant tumor protein 53; OTTMUSP00000006194; p44; p53; p53 cellular tumor antigen; p53 protein; p53 tumor suppressor; p53 tumor suppressor phosphoprotein; phosphoprotein p53; Tp53; tp53.L; transformation related protein 53; transformation-related protein 53; Trp248; Trp53; tumor protein 53; tumor protein p53; tumor protein p53 (Li-Fraumeni syndrome); tumor protein p53 L homeolog; tumor suppressor p53; tumor suppressor p53 phosphoprotein; tumor suppressor protein p53; tumor supressor p53; Tumour Protein p53; XELAEV_180196761mg; Xp53; Xrel3

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
7157

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.22 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.:
P04637

Gene Symbols:
Tp53

Immunogen:
A synthetic phosphorylated peptide around S6 of human p53 (NP_0005373)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5117236

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Antigen:
Phospho-MYL9 (Thr18, Ser19)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MYL9

Gene Alias:
20 kDa myosin light chain; AI327049; DTNB; G1; Isoform L20-A; LC20; light polypeptide 9; MGC3505; MLC2; MLC-2; MLC20; MLC-2C; MRLC1; myl9; myl9.L; myl9b; myl9l; Mylc2c; myosin light chain 2; myosin light chain 9; myosin light chain 9 L homeolog; myosin light chain, regulatory C; myosin regulatory light chain; myosin regulatory light chain 1; myosin regulatory light chain 2, smooth muscle isoform; Myosin regulatory light chain 2, smooth muscle major isoform; myosin regulatory light chain 9; Myosin regulatory light chain MRLC1; myosin regulatory light polypeptide 9; myosin regulatory light polypeptide 9b; myosin RLC; myosin, light chain 9, regulatory; myosin, light chain 9b, regulatory; myosin, light polypeptide 9, regulatory; Myrl2; RLC-C; smooth muscle major isoform; unnamed protein product; XELAEV_18003093mg; zgc:77916

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10398, 296313, 98932

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.93 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.:
P24844, Q64122, Q9CQ19

Gene Symbols:
MYL9

Immunogen:
A synthetic phosphorylated peptide around T18 & S19 of human MYL9 (NP_0060882)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG