PIPA5114995

CD86 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5114995-Each-of-1 In Stock ₹ 44,705.10

PIPA5114995 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

CD86

Classification

Polyclonal

Conjugate

Unconjugated

Gene

CD86

Gene Alias

activation B7-2 antigen; B lymphocyte activation antigen B72; B7; B7.2; B70; B7-2; B-lymphocyte activation antigen B7-2; BU63; CD28 antigen ligand 2; Cd28l2; CD28LG2; CD86; CD86 antigen; CD86 antigen (CD28 antigen ligand 2, B7-2 antigen); CD86 antigen precursor; CD86 molecule; CLS1; CTLA-4 counter-receptor B7.2; early T cell costimulatory molecule-1; early T-cell costimulatory molecule 1; Early T-cell co-stimulatory molecule 1; ETC-1; FUN-1; LAB72; Ly58; Ly-58; MB7; MB7-2; membrane glycoprotein; MGC34413; T-lymphocyte activation antigen CD86; TS/A-2

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

12524, 942

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (PFA fixed), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.

P42081, P42082

Gene Symbols

CD86

Immunogen

A synthesized peptide derived from human CD86(Accession P42081), corresponding to amino acid residues E52-I102.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total CD86
  • CD86 is one of two ligands (the other CD80) for CTLA4 and CD28
  • CD86 acts as costimulatory molecule in eliciting T-cell help during antigen presentation
  • Antigen presentation in the absence of sufficient co-stimulation involving CD86/CD80 can induce tolerance
  • CD80 appears to play a role distinct from CD80 in T helper cell differentiation
  • CD86 is a type I membrane protein that is a member of the immunoglobulin superfamily
  • The CD86 protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4
  • Binding of CD86 with CD28 antigen is a costimulatory signal for activation of the T-cell
  • Binding of CD86 with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response
  • Alternative splicing results in two transcript variants encoding different isoforms of CD86
  • Additional transcript variants have been described for CD86, but their full-length sequences have not been determined
  • Diseases associated with CD86 dysfunction include gallbladder squamous cell carcinoma and myocarditis.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA5114995

--


Antigen:
CD86

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CD86

Gene Alias:
activation B7-2 antigen; B lymphocyte activation antigen B72; B7; B7.2; B70; B7-2; B-lymphocyte activation antigen B7-2; BU63; CD28 antigen ligand 2; Cd28l2; CD28LG2; CD86; CD86 antigen; CD86 antigen (CD28 antigen ligand 2, B7-2 antigen); CD86 antigen precursor; CD86 molecule; CLS1; CTLA-4 counter-receptor B7.2; early T cell costimulatory molecule-1; early T-cell costimulatory molecule 1; Early T-cell co-stimulatory molecule 1; ETC-1; FUN-1; LAB72; Ly58; Ly-58; MB7; MB7-2; membrane glycoprotein; MGC34413; T-lymphocyte activation antigen CD86; TS/A-2

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12524, 942

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (PFA fixed), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P42081, P42082

Gene Symbols:
CD86

Immunogen:
A synthesized peptide derived from human CD86(Accession P42081), corresponding to amino acid residues E52-I102.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5114997

--


Antigen:
Cdc5L

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CDC5L

Gene Alias:
1200002I02Rik; AA408004; CDC5; CDC5 cell division cycle 5-like; CDC5 cell division cycle 5-like (S. pombe); CDC5L; CDC5-LIKE; Cdc5-like protein; Cdc5-related protein; CEF1; cell division cycle 5 like; cell division cycle 5-like; cell division cycle 5-like (S. pombe); cell division cycle 5-like protein; cell division cycle 5-related protein; dJ319D22.1; dJ319D22.1 (CDC5-like protein); hCDC5; KIAA0432; Pcdc5rp; Pombe cdc5-related protein; Unknown (protein for MGC:128482); zgc:55853

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
71702, 85434, 988

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (PFA fixed), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.:
O08837, Q6A068, Q99459

Gene Symbols:
CDC5L

Immunogen:
A synthesized peptide derived from human CDC5L(Accession Q99459), corresponding to amino acid residues G207-G257.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5114998

--


Antigen:
H-cadherin

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CDH13

Gene Alias:
4932416G01Rik; CAD13; cadherin 13; cadherin 13, H-cadherin (heart); cadherin-13; CD39 antigen-like 3; CD39L3; CD39-like 3; CDH13; CDHH; Cdht; ecto-apyrase 3; ecto-ATPase 3; ecto-ATPDase 3; HB6; H-cadherin; H-cadherin (heart); heart cadherin; heart-cadherin; NTPDase 3; NTPDase-3; P105; T cad; T Cadherin; Tcad; T-cad; T-cadherin; Truncated cadherin; truncated-cadherin

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1012, 12554

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P55290, Q9WTR5

Gene Symbols:
CDH13

Immunogen:
A synthesized peptide derived from human CDH13(Accession P55290), corresponding to amino acid residues P144-T194.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5114999

--


Antigen:
Cdk3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Cdk3

Gene Alias:
2310050O10Rik; Cdk3; Cdk3-ps; CDKN3; Cell division protein kinase 3; cyclin dependent kinase 3; cyclin-dependent kinase 3; cyclin-dependent kinase 3, pseudogene

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1018, 69681

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q00526

Gene Symbols:
Cdk3

Immunogen:
A synthesized peptide derived from human CDK3(Accession Q00526), corresponding to amino acid residues D261-H305.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG