PIPA5115530

MACC1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5115530-Each-of-1 In Stock ₹ 44,705.10

PIPA5115530 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

MACC1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

MACC1

Gene Alias

4732474O15Rik; 7A5; Gm267; MACC1; metastasis associated in colon cancer 1; metastasis-associated in colon cancer protein 1; putative binding protein 7a5; RGD1309838; SH3 domain-containing protein 7a5; SH3BP4L

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

238455, 314539, 346389

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.

Q6ZN28

Gene Symbols

MACC1

Immunogen

A synthesized peptide derived from human MACC1(Accession Q6ZN28), corresponding to amino acid residues N86-R136.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total MACC1
  • MACC1 (Metastasis associated in colon cancer 1) is a key regulator of the hepatocyte growth factor (HGF)-HGF receptor (MET) pathway, which is involved in cellular growth, epithelial-mesenchymal transition, angiogenesis, cell motility, invasiveness, and metastasis
  • MACC1 protein consists of four domains: ZU5, SH3, and two C-terminal death domains (DD)
  • Expression of MACC1 was found significantly upregulated in malignant tissues (colon cancer of all stages as well as liver and lung metastases) compared to normal tissues or adenomas
  • MACC1 represents an early and crucial prognostic indicator for colon cancer metastasis that is independent of age, sex, tumor infiltration, nodal status, and lymph vessel invasion
  • Besides its involvement in signal transduction with the MET receptor, MACC1 also links MET signaling and apoptosis
  • MACC1 may also be an important therapeutic target for colorectal cancer treatment
  • At least two isoforms of MACC1 are known to exist.

Compare Similar Items

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Img

Thermo Scientific

PIPA5115530

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Antigen:
MACC1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MACC1

Gene Alias:
4732474O15Rik; 7A5; Gm267; MACC1; metastasis associated in colon cancer 1; metastasis-associated in colon cancer protein 1; putative binding protein 7a5; RGD1309838; SH3 domain-containing protein 7a5; SH3BP4L

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
238455, 314539, 346389

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q6ZN28

Gene Symbols:
MACC1

Immunogen:
A synthesized peptide derived from human MACC1(Accession Q6ZN28), corresponding to amino acid residues N86-R136.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5115531

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Antigen:
H2AFY2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
H2AFY2

Gene Alias:
Core histone macro-H2A.2; core histone macroH2A2.2; H2A histone family member Y2; H2A histone family, member Y2; H2AFY2; H2afy3; Histone macroH2A2; histone mH2A2; macroH2A2; mH2A2; RGD1561371

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
361844, 404634, 55506

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q8CCK0, Q9P0M6

Gene Symbols:
H2AFY2

Immunogen:
A synthesized peptide derived from human H2AFY2(Accession Q9P0M6), corresponding to amino acid residues E288-F338.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5115532

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Antigen:
Histone Macro-H2A.1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MACROH2A1

Gene Alias:
Core histone macro-H2A.1; H2A histone family member Y; H2A histone family, member Y; H2A.y; H2A/y; H2AF12M; H2AFY; Histone H2A.y; histone macroH2A1; histone macroH2A1.1; histone macroH2A1.2; macroH2A1; MACROH2A1.1; macroH2A1.2; medulloblastoma antigen MU-MB-50.205; mH2A1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
26914, 29384, 9555

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.:
O75367, Q02874, Q9QZQ8

Gene Symbols:
MACROH2A1

Immunogen:
A synthesized peptide derived from human H2AFY(Accession O75367), corresponding to amino acid residues K292-M342.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5115534

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Antigen:
MAFK

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MAFK

Gene Alias:
AW061068; basic-leucine zipper transcription factor MafK; erythroid transcription factor NF-E2 p18 subunit; FLJ32205; MAF bZIP transcription factor K; Mafk; MGC71717; NF-E2; Nfe2u; nuclear factor erythroid-2, ubiquitous (p18); nuclear factor, erythroid derived 2, ubiquitous; P18; p18 NF-E2; transcription factor MafK; v-maf avian musculoaponeurotic fibrosarcoma oncogene family, protein K; v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K; v-maf musculoaponeurotic fibrosarcoma oncogene family, protein K; v-maf musculoaponeurotic fibrosarcoma oncogene family, protein K (avian); v-maf musculoaponeurotic fibrosarcoma oncogene homolog K

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
17135, 246760, 7975

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.:
O60675, Q61827

Gene Symbols:
MAFK

Immunogen:
A synthesized peptide derived from human MAFK(Accession O60675), corresponding to amino acid residues M1-K46.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG