PIPA5116132

XAF1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5116132-Each-of-1 In Stock ₹ 44,705.10

PIPA5116132 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

XAF1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

XAF1

Gene Alias

BIRC4 binding protein; BIRC4-binding protein; Birc4bp; F-box protein 39; Fbox39; HSXIAPAF1; novel TRAF-type zinc finger protein; XAF1; XIAP associated factor 1; XIAP associated factor-1; Xiapaf1; XIAP-associated factor 1

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

327959, 54739, 679600

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.

Q5NBU8, Q6GPH4

Gene Symbols

XAF1

Immunogen

A synthesized peptide derived from human XAF1(Accession Q6GPH4), corresponding to amino acid residues H223-L273.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total XAF1
  • The inhibitors of apoptosis (IAP) proteins prevent cell death both in vitro and in vivo by virtue of inhibition of distinct caspases
  • The X-linked Inhibitor of Apoptosis, XIAP, is a key member of the IAP family of proteins
  • The caspase inhibiting activity of XIAP is negatively regulated by at least two XIAP-interacting proteins, XIAP-associated factor 1 (XAF1) and Smac/DIABLO
  • XAF1 binds to XIAP and antagonizes caspase inhibitory activities of XIAP
  • Expression of XAF1 triggers a redistribution of XIAP from the cytosol to the nucleus
  • XAF1 is ubiquitously expressed in normal tissues, but is present at low or undetectable levels in many different cancer cell lines.

Compare Similar Items

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Img

Thermo Scientific

PIPA5116132

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Antigen:
XAF1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
XAF1

Gene Alias:
BIRC4 binding protein; BIRC4-binding protein; Birc4bp; F-box protein 39; Fbox39; HSXIAPAF1; novel TRAF-type zinc finger protein; XAF1; XIAP associated factor 1; XIAP associated factor-1; Xiapaf1; XIAP-associated factor 1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
327959, 54739, 679600

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q5NBU8, Q6GPH4

Gene Symbols:
XAF1

Immunogen:
A synthesized peptide derived from human XAF1(Accession Q6GPH4), corresponding to amino acid residues H223-L273.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5116134

--


Antigen:
SLC7A11

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SLC7A11

Gene Alias:
9930009M05Rik; AI451155; Amino acid transport system xc-; calcium channel blocker resistance protein CCBR1; CCBR1; cysteine/glutamate transporter; cystine/glutamate transporter; SLC7A11; sodium independent anionic amino acid transport system; solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11; solute carrier family 7 (cationic amino acid transporter, y+ system), member 11; solute carrier family 7 member 11; solute carrier family 7, (cationic amino acid transporter, y+ system) member 11; sut; xCT

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
23657, 26570, 310392

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q9UPY5, Q9WTR6

Gene Symbols:
SLC7A11

Immunogen:
A synthesized peptide derived from human SLC7A11(Accession Q9UPY5), corresponding to amino acid residues T195-A245.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5116135

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Antigen:
XLF

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NHEJ1

Gene Alias:
1700029B21Rik; cernunnos; FLJ12610; Nhej1; non-homologous end joining factor 1; non-homologous end-joining factor 1; nonhomologous end-joining factor 1; protein cernunnos; Xlf; XRCC4-like factor

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
79840

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q9H9Q4

Gene Symbols:
NHEJ1

Immunogen:
A synthesized peptide derived from human NHEJ1(Accession Q9H9Q4), corresponding to amino acid residues M212-S262.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5116136

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Antigen:
XPA

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
XPA

Gene Alias:
AI573865; DNA repair protein complementing XP-A cells; DNA repair protein complementing XP-A cells homolog; excision repair-controlling; mutant xeroderma pigmentosum complementation group A; xeroderma pigmentosum group A-complementing protein; Xeroderma pigmentosum group A-complementing protein homolog; xeroderma pigmentosum, complementation group A; XP1; XPA; XPA, DNA damage recognition and repair factor; Xpac

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
22590, 7507

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P23025, Q64267

Gene Symbols:
XPA

Immunogen:
A synthesized peptide derived from human XPA(Accession P23025), corresponding to amino acid residues H171-K221.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG