p14ARF Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5115701-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA5115701 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
p14ARF
Classification
Polyclonal
Conjugate
Unconjugated
Gene
CDKN2A
Gene Alias
Alternative reading frame; ARF; ARF-INK4a; CDK4 inhibitor p16-INK4; CDK4I; CDKN2; CDKN2A; cdkn2a {ECO:0000312; cell cycle inhibitor; cell cycle negative regulator beta; cell cycle regulator; CMM2; cyclin dependent kinase inhibitor 2A; Cyclin dependent kinase inhibitor 2A (p16, inhibits CDK4); cyclin-dependent kinase 4 inhibitor A; Cyclin-dependent kinase inhibitor 2A; cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4); cyclin-dependent kinase inhibitor 2A (p16, inhibits CDK4); cyclin-dependent kinase inhibitor 2a p16Ink4a; cyclin-dependent kinase inhibitor 2a p19Arf; cyclin-dependent kinase inhibitor 2A, isoform 1; cyclin-dependent kinase inhibitor 2A, isoform 2; cyclin-dependent kinase inhibitor 2A, isoform 3; cyclin-dependent kinase inhibitor 2A, isoforms 1/2; cyclin-dependent kinase inhibitor protein; EMBL:AAL76336.1, ECO:0000312; EMBL:AAL76338.1, ECO:0000312; inhibits CDK4; INK4; INK4A; Ink4a/Arf; INK4a-ARF; mitochondrial smARF; MLM; MTS1; MTS-1; Multiple tumor suppressor 1; P14; p14 p16; P14ARF; p16; p16(INK4a); p16Cdkn2a; P16INK4; p16-INK4; P16INK4A; P16-INK4A; P19; P19 TP16; p19<ARF>; P19ARF; Pctr1; RGD:2323}; TP16; Tumor suppressor ARF
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
1029, 25163
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.
P42771, Q8QZZ9
Gene Symbols
CDKN2A
Immunogen
A synthesized peptide derived from human CDKN2A(Accession Q8N726), corresponding to amino acid residues L50-G74.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of total p14 ARF
- The INK4a locus on chromosome 9p21 is frequently affected in human tumors
- It encodes two structurally distinct tumor suppressor proteins, p16INK4a and the alternative reading frame protein, ARF (p14ARF in human and P19ARF in mouse)
- These two proteins interact with the upstream proteins: retinoblastoma protein and p53 tumor suppressors, respectively
- Each of these proteins has a role in the senescence of primary cells, activates pathways for cell cycle control and tumor suppression
- The p14ARF (or P19ARF in mouse) proteins can induce both G1 and G2 phase arrest in a manner that depends on functional p53
- The mouse and human ARF proteins have different functions in tumor suppression; this distinction may contribute to the different levels of tumor proneness of these species.
Compare Similar Items
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Antigen: p14ARF
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CDKN2A
Gene Alias: Alternative reading frame; ARF; ARF-INK4a; CDK4 inhibitor p16-INK4; CDK4I; CDKN2; CDKN2A; cdkn2a {ECO:0000312; cell cycle inhibitor; cell cycle negative regulator beta; cell cycle regulator; CMM2; cyclin dependent kinase inhibitor 2A; Cyclin dependent kinase inhibitor 2A (p16, inhibits CDK4); cyclin-dependent kinase 4 inhibitor A; Cyclin-dependent kinase inhibitor 2A; cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4); cyclin-dependent kinase inhibitor 2A (p16, inhibits CDK4); cyclin-dependent kinase inhibitor 2a p16Ink4a; cyclin-dependent kinase inhibitor 2a p19Arf; cyclin-dependent kinase inhibitor 2A, isoform 1; cyclin-dependent kinase inhibitor 2A, isoform 2; cyclin-dependent kinase inhibitor 2A, isoform 3; cyclin-dependent kinase inhibitor 2A, isoforms 1/2; cyclin-dependent kinase inhibitor protein; EMBL:AAL76336.1, ECO:0000312; EMBL:AAL76338.1, ECO:0000312; inhibits CDK4; INK4; INK4A; Ink4a/Arf; INK4a-ARF; mitochondrial smARF; MLM; MTS1; MTS-1; Multiple tumor suppressor 1; P14; p14 p16; P14ARF; p16; p16(INK4a); p16Cdkn2a; P16INK4; p16-INK4; P16INK4A; P16-INK4A; P19; P19 TP16; p19<ARF>; P19ARF; Pctr1; RGD:2323}; TP16; Tumor suppressor ARF
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 1029, 25163
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.: P42771, Q8QZZ9
Gene Symbols: CDKN2A
Immunogen: A synthesized peptide derived from human CDKN2A(Accession Q8N726), corresponding to amino acid residues L50-G74.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Rat
Product Type: Antibody
Isotype: IgG
Antigen: p27 Kip1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Cdkn1b
Gene Alias: AA408329; AI843786; Cdki1b; CDKN1B; CDKN4; CDN1B; cyclin dependent kinase inhibitor 1B; cyclin-dependent kinase inhibitor 1B; Cyclin-dependent kinase inhibitor 1B (p27 Kip1); Cyclin-dependent kinase inhibitor 1B (p27, Kip1); cyclin-dependent kinase inhibitor p27; Cyclin-dependent kinase inhibitor p27 Kip1; cyclin-dependent kinase inhibitor p27/Kip1; KIP1; MEN1B; MEN4; p27; P27 CDKN1B; p27(KIP1); p27Kip1
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 1027, 12576, 83571
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (PFA fixed), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.: P46414, P46527
Gene Symbols: Cdkn1b
Immunogen: A synthesized peptide derived from human CDKN1B(Accession P46527), corresponding to amino acid residues P133-S183.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen: P2X2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: P2RX2
Gene Alias: ATP receptor; DFNA41; MGC129601; P2RX2; P2X purinoceptor 2; P2X Receptor, subunit 2; P2X2; P2X2 purinoceptor; P2X2 receptor splice variant P2X2-1; P2X2 receptor splice variant P2X2-2; P2X2 receptor splice variant P2X2-3; P2X2a; Purinergic receptor; purinergic receptor P2X 2; purinergic receptor P2X, ligand gated ion channel, 2; purinergic receptor P2X, ligand-gated ion channel, 2; purinergic receptor P2X2
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 22953, 231602
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.: Q8K3P1, Q9UBL9
Gene Symbols: P2RX2
Immunogen: A synthesized peptide derived from human P2RX2(Accession Q9UBL9), corresponding to amino acid residues H408-Q458.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
