PIPA5115715

PAI1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5115715-Each-of-1 In Stock ₹ 44,705.10

PIPA5115715 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

PAI1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Serpine1

Gene Alias

Endothelial plasminogen activator inhibitor; nexin, plasminogen activator inhibitor type 1; PAI; PAI1; PAI-1; PAI1 protein; PAI1A; Pai1aa; Planh; Planh1; plas; plasminogen activator inhibitor; plasminogen activator inhibitor 1; plasminogen activator inhibitor I; plasminogen activator inhibitor, type I; plasminogen activator inhibitor-1; Plasminogen activator inhibitor-1 precursor (PAI-1) (Endothelial plasminogen activator inhibitor) (PAI); putative plasminogen activator inhibitor-1; RATPAI1A; serine (or cysteine) peptidase inhibitor, clade E, member 1; serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; serine (or cysteine) proteinase inhibitor, clade E, member 1; serine (or cysteine) proteinase inhibitor, member 1; serpin E1; serpin family E member 1; serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; SERPINE1; SERPINE-1

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

5054

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.

P05121

Gene Symbols

Serpine1

Immunogen

A synthesized peptide derived from human SERPINE1(Accession P05121), corresponding to amino acid residues I282-L332.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total PAI 1
  • PAI1 (plasminogen activator inhibitor 1) belongs to serine protease inhibitor superfamily, and is the principal inhibitor of tissue-type and urokinase-type plasminogen activators (tPA and uPA)
  • Platelets are the main source of the circulating PAI11, but it is synthesized and secreted by many tissue and cell types, including fibroblasts, smooth muscle cells, endothelial cells, hepatocytes, and inflammatory cells
  • Expression of PAI11 can be regulated at the transcriptional level by many factors including growth factors, cytokines, hormones, inflammatory factors, glucose or lipid metabolites, vascular tone regulating factors, chemicals, and other environmental or physical factors
  • PAI1 is present at increased levels in various disease states, and has been linked to an increased occurrence of thrombosis in obesity, thrombophilia and the metabolic syndrome
  • Defects in PAI-1 are characterized by abnormal bleeding
  • PAI1 mediates inhibition of fibrinolysis by inhibiting the activity of plasminogen activator, and may promote neuronal survival
  • Other defects in PAI1 are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency)
  • Alternatively spliced transcript variants encoding different isoforms of PAI1 have been found.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA5115715

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Antigen:
PAI1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Serpine1

Gene Alias:
Endothelial plasminogen activator inhibitor; nexin, plasminogen activator inhibitor type 1; PAI; PAI1; PAI-1; PAI1 protein; PAI1A; Pai1aa; Planh; Planh1; plas; plasminogen activator inhibitor; plasminogen activator inhibitor 1; plasminogen activator inhibitor I; plasminogen activator inhibitor, type I; plasminogen activator inhibitor-1; Plasminogen activator inhibitor-1 precursor (PAI-1) (Endothelial plasminogen activator inhibitor) (PAI); putative plasminogen activator inhibitor-1; RATPAI1A; serine (or cysteine) peptidase inhibitor, clade E, member 1; serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; serine (or cysteine) proteinase inhibitor, clade E, member 1; serine (or cysteine) proteinase inhibitor, member 1; serpin E1; serpin family E member 1; serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; SERPINE1; SERPINE-1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5054

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P05121

Gene Symbols:
Serpine1

Immunogen:
A synthesized peptide derived from human SERPINE1(Accession P05121), corresponding to amino acid residues I282-L332.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5115716

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Antigen:
PAK5/PAK6

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PAK5

Gene Alias:
2900083L08Rik; 4732456M09; 6430627N20; KIAA1142; KIAA1264; p21 (CDKN1A)-activated kinase 6; p21 (CDKN1A)-activated kinase 7; p21 (RAC1) activated kinase 5; p21 (RAC1) activated kinase 6; p21 (RAC1) activated kinase 7; p21 protein (Cdc42/Rac)-activated kinase 6; p21 protein (Cdc42/Rac)-activated kinase 7; p21(CDKN1A)-activated kinase 6; p21(CDKN1A)-activated kinase 7; p21-activated kinase 5; p21-activated kinase 6; p21-activated kinase 7; p21CDKN1A-activated kinase 7; PAK4; PAK-4; PAK5; PAK-5; Pak6; PAK-6; Pak7; PAK-7; protein kinase PAK5; Serine/threonine-protein kinase PAK 5; Serine/threonine-protein kinase PAK 6; serine/threonine-protein kinase PAK 7; serine/threonine-protein kinase PAK7

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
214230, 241656, 296078, 311450, 56924, 57144

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.:
D4A280, Q3ULB5, Q8C015, Q9NQU5, Q9P286

Gene Symbols:
PAK5, PAK6, Pak7

Immunogen:
A synthesized peptide derived from human PAK5/6.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5115717

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Antigen:
PAK5

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PAK5

Gene Alias:
2900083L08Rik; 6430627N20; KIAA1264; p21 (CDKN1A)-activated kinase 7; p21 (RAC1) activated kinase 5; p21 (RAC1) activated kinase 7; p21 protein (Cdc42/Rac)-activated kinase 7; p21(CDKN1A)-activated kinase 7; p21-activated kinase 5; p21-activated kinase 7; p21CDKN1A-activated kinase 7; PAK5; PAK-5; Pak7; PAK-7; protein kinase PAK5; RP5-1119D9.3; Serine/threonine-protein kinase PAK 5; serine/threonine-protein kinase PAK 7; serine/threonine-protein kinase PAK7

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
241656, 311450, 57144

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.:
D4A280, Q8C015, Q9P286

Gene Symbols:
PAK5, Pak7

Immunogen:
A synthesized peptide derived from human PAK5(Accession Q9P286), corresponding to amino acid residues S286-A336.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA5115718

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Antigen:
Methylated Lysine

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
__

Gene Alias:
Dimethylysine; Methyl lysine; Trimethyl lysine

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
A synthesized peptide derived from human Pan Methylated Lysine, corresponding to a region within C-terminal amino acids.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Chemical

Product Type:
Antibody

Isotype:
IgG