PIPA5115885

PEDF Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5115885-Each-of-1 In Stock ₹ 44,705.10

PIPA5115885 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

PEDF

Classification

Polyclonal

Conjugate

Unconjugated

Gene

SERPINF1

Gene Alias

AI195227; alpha-2 antiplasmin; caspin; Cell proliferation-inducing gene 35 protein; Dmrs91; EPC 1; EPC1; EPC-1; OI12; OI6; PEDF; Pedfl; PIG 35; PIG35; pigment epithelium derived factor; pigment epithelium-derived factor; Sdf3; SDF-3; serine (or cysteine) peptidase inhibitor, clade F, member 1; serine (or cysteine) proteinase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1; serine (or cysteine) proteinase inhibitor, clade F), member 1; serine (or cysteine) proteinase inhibitor, clade F, member 1; serpin F1; serpin family F member 1; serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1; serpin peptidase inhibitor, clade F, member 1; SERPINF 1; Serpinf1; serpin-F1; sserpin family F member 1; stromal cell derived factor 3; stromal cell-derived factor 3; testis tissue sperm-binding protein Li 70n

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

20317, 287526, 5176

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (PFA fixed), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.

P36955, P97298

Gene Symbols

SERPINF1

Immunogen

A synthesized peptide derived from human SERPINF1(Accession P36955), corresponding to amino acid residues V325-P375.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total SERPINF1
  • PEDF is a noninhibitory serpin with neurotrophic, anti-angiogenic, and anti-tumorigenic properties
  • It is a 50 kDa glycoprotein produced and secreted in many tissues throughout the body
  • A major component of the anti-angiogenic action of PEDF is the induction of apoptosis in proliferating endothelial cells
  • In addition, PEDF is able to inhibit the activity of angiogenic factors, such as VEGF and FGF-2
  • The neuroprotective effects of PEDF are achieved through suppression of neuronal apoptosis induced by peroxide, glutamate, or other neurotoxins
  • The recent identification of a lipase-linked cell membrane receptor for PEDF (PEDF-R) that binds to PEDF with high affinity (1) should facilitate further elucidation of the underlying mechanisms of this pluripotent serpin
  • To date, PEDF-R is the only signaling receptor known to be used by a serpin family member
  • The unique range of PEDF activities implicate it as a potential therapeutic agent for the treatment of vasculature-related neurodegenerative diseases, such as age-related macular degeneration (AMD) and proliferative diabetic retinopathy (PDR)
  • PEDF also has the potential to be useful in the treatment of various angiogenesis-related diseases including a number of cancers.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA5115885

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Antigen:
PEDF

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SERPINF1

Gene Alias:
AI195227; alpha-2 antiplasmin; caspin; Cell proliferation-inducing gene 35 protein; Dmrs91; EPC 1; EPC1; EPC-1; OI12; OI6; PEDF; Pedfl; PIG 35; PIG35; pigment epithelium derived factor; pigment epithelium-derived factor; Sdf3; SDF-3; serine (or cysteine) peptidase inhibitor, clade F, member 1; serine (or cysteine) proteinase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1; serine (or cysteine) proteinase inhibitor, clade F), member 1; serine (or cysteine) proteinase inhibitor, clade F, member 1; serpin F1; serpin family F member 1; serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1; serpin peptidase inhibitor, clade F, member 1; SERPINF 1; Serpinf1; serpin-F1; sserpin family F member 1; stromal cell derived factor 3; stromal cell-derived factor 3; testis tissue sperm-binding protein Li 70n

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20317, 287526, 5176

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (PFA fixed), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P36955, P97298

Gene Symbols:
SERPINF1

Immunogen:
A synthesized peptide derived from human SERPINF1(Accession P36955), corresponding to amino acid residues V325-P375.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5115889

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Antigen:
SFRS12

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SREK1

Gene Alias:
8430401B01; AI450757; AI462342; serine/arginine-rich splicing factor 12; serine/arginine-rich-splicing regulatory protein 86; serine-arginine-rich splicing regulatory protein 508; serine-arginine-rich splicing regulatory protein 86; serine-arginine-rich-splicing regulatory protein 86; SFRS12; Splicing factor, arginine/serine-rich 12; splicing regulatory glutamic acid and lysine rich protein 1; splicing regulatory glutamic acid/lysine-rich protein 1; splicing regulatory glutamine/lysine-rich protein 1; Splicing regulatory protein 508; Srek1; SR-related protein of 86 kDa; SRrp508; Srrp86; Srsf12

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
140890, 218543, 56763

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q8BZX4, Q8WXA9, Q9JKL7

Gene Symbols:
SREK1

Immunogen:
A synthesized peptide derived from human SREK1(Accession Q8WXA9), corresponding to amino acid residues S192-R242.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5115893

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Antigen:
SHANK3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Shank3

Gene Alias:
AI841104; DEL22q13.3; Kiaa1650; proline rich synapse associated protein 2; proline-rich synapse-associated protein 2; PROSAP2; PSAP2; SCZD15; SH3 and multiple ankyrin repeat domains 3; SH3 and multiple ankyrin repeat domains protein 3; SH3 and multiple ankyrin repeat domains protein 3 variant c-3; SH3 and multiple ankyrin repeat domains protein 3 variant c-4; SH3 and multiple ankyrin repeat domains-like protein 3 variant 1; SH3 and multiple ankyrin repeat domains-like protein 3 variant 2; SH3 and multiple ankyrin repeat domains-like protein 3 variant 3; SH3 and multiple ankyrin repeat domains-like protein 3 variant c-1; SH3 and multiple ankyrin repeat domains-like protein 3 variant c-2; SH3 and multiple ankyrin repeat domains-like protein 3 variant d-1; SH3 and multiple ankyrin repeat domains-like protein 3 variant d-2; SH3 and multiple ankyrin repeat domains-like protein 3 variant d-3; SH3 and multiple ankyrin repeat domains-like protein 3 variant e-1; SH3 and multiple ankyrin repeat domains-like protein 3 variant e-2; SH3/ankyrin domain gene 3; shank postsynaptic density protein; Shank postsynaptic density protein 3a; SHANK3; shank3 splice variant II; shank3 splice variant III; shank3 splice variant IV; Shank3b; SHANK3c-3; SHANK3c-4; shank3e splice variant III; shank3e splice variant IV; SPANK 2; SPANK2; SPANK-2

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
58234, 59312, 85358

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q4ACU6, Q9BYB0, Q9JLU4

Gene Symbols:
Shank3

Immunogen:
A synthesized peptide derived from human SHANK3(Accession Q9BYB0), corresponding to amino acid residues T750-S800.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5115894

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Antigen:
SHIP1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
INPP5D

Gene Alias:
7a33; hp51CN; Inositol polyphosphate-5-phosphatase 145 kDa; inositol polyphosphate-5-phosphatase D; Inositol polyphosphate-5-phosphatase of 145 kDa; inositol polyphosphate-5-phosphatase, 145 kDa; inositol polyphosphate-5-phosphatase, 145kD; inositol polyphosphate-5-phosphatase, 145kDa; Inpp5d; MGC104855; MGC142140; MGC142142; OTTHUMP00000165069; OTTHUMP00000165070; OTTHUMP00000165071; OTTHUMP00000165072; OTTHUMP00000203442; p150Ship; phosphatidylin; Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1; Phosphatidylinositol 4,5-bisphosphate 5-phosphatase; phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1; Phosphatidylinositol-4,5-bisphosphate 5-phosphatase; SH2 domain-containing inositol 5'-phosphatase 1; SH2 domain-containing inositol phosphatase 1; SH2 domain-containing inositol-5'-phosphatase 1; SH2-containing inositol phosphatase SHIP; SHIP; SHIP1; SHIP-1; signaling inositol polyphosphate 5 phosphatase SIP-145; signaling inositol polyphosphate phosphatase SHIP II; SIP-145; Src homology 2 domain-containing inositol-5-phosphatase; s-SHIP

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16331, 3635

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q92835, Q9ES52

Gene Symbols:
INPP5D

Immunogen:
A synthesized peptide derived from human INPP5D(Accession Q92835), corresponding to amino acid residues H839-P889.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG