PIPA5115793

PSEN2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA5115793-Each-of-1 In Stock ₹ 44,705.10

PIPA5115793 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

PSEN2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

PSEN2

Gene Alias

AD3L; AD3LP; AD4; Ad4h; AD5; Alg3; ALG-3; Alzheimer disease 4; CMD1V; E5-1; presenilin 2; presenilin-2; Presenilin-2 CTF subunit; Presenilin-2 NTF subunit; PS2; Ps-2; PSEN 2; PSEN2; Psnl2; STM2; STM-2

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

19165, 5664, 81751

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (PFA fixed), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.

O88777, P49810, Q61144

Gene Symbols

PSEN2

Immunogen

A synthesized peptide derived from human PSEN2(Accession P49810), corresponding to amino acid residues K306-E356.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total Presenilin 2
  • Alzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1 or PSEN2) or the amyloid precursor protein (APP)
  • These disease-linked mutations result in increased production of the longer form of amyloid-beta (main component of amyloid deposits found in AD brains)
  • Presenilins are postulated to regulate APP processing through their effects on gamma-secretase, an enzyme that cleaves APP
  • Also, it is thought that the presenilins are involved in the cleavage of the Notch receptor such that, they either directly regulate gamma-secretase activity, or themselves act are protease enzymes
  • Two alternatively spliced transcript variants encoding different isoforms of PSEN2 have been identified.

Compare Similar Items

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Thermo Scientific

PIPA5115793

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Antigen:
PSEN2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PSEN2

Gene Alias:
AD3L; AD3LP; AD4; Ad4h; AD5; Alg3; ALG-3; Alzheimer disease 4; CMD1V; E5-1; presenilin 2; presenilin-2; Presenilin-2 CTF subunit; Presenilin-2 NTF subunit; PS2; Ps-2; PSEN 2; PSEN2; Psnl2; STM2; STM-2

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
19165, 5664, 81751

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (PFA fixed), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.:
O88777, P49810, Q61144

Gene Symbols:
PSEN2

Immunogen:
A synthesized peptide derived from human PSEN2(Accession P49810), corresponding to amino acid residues K306-E356.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5115795

--


Antigen:
PRMT3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Prmt3

Gene Alias:
2010005E20Rik; 2410018A17Rik; AL033309; heterogeneous nuclear ribonucleoprotein methyltransferase-like 3; heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 3; HMT1 hnRNP methyltransferase-like 3; Hrmt1l3; PRMT3; protein arginine methyltransferase 3; protein arginine N-methyltransferase 3; protein arginine N-methyltransferase 3(hnRNP methyltransferase S. cerevisiae)-like 3

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10196, 71974, 89820

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.:
O60678, O70467, Q922H1

Gene Symbols:
Prmt3

Immunogen:
A synthesized peptide derived from human PRMT3(Accession O60678), corresponding to amino acid residues M331-A381.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5115798

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Antigen:
PREP

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PREP

Gene Alias:
AI047692; AI450383; D10Wsu136e; dJ355L5.1 (prolyl endopeptidase); EC 3.4.21.26; MGC16060; PE; PE {ECO:0000250; PEP; Pop; post-proline cleaving enzyme; post-proline cleaving enzyme {ECO:0000250; Prep; prep {ECO:0000312; Prolyl endopeptidase; prolyl endopeptidase {ECO:0000250; prolyl oligopeptidase; RGD:620841}; rPop; UniProtKB:P23687}

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
19072, 5550, 83471

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.:
O70196, P48147, Q9QUR6

Gene Symbols:
PREP

Immunogen:
A synthesized peptide derived from human PREP(Accession P48147), corresponding to amino acid residues L168-D218.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5115799

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Antigen:
PSCA

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PSCA

Gene Alias:
2210408B04Rik; caldesmon; CDM; HCAD; H-CAD; LCAD; L-CAD; NAG22; PRO232; prostate stem cell antigen; PSCA; UNQ206; UNQ206/PRO232

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
680210, 72373, 8000

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.:
O43653, P57096

Gene Symbols:
PSCA

Immunogen:
A synthesized peptide derived from human PSCA(Accession O43653), corresponding to amino acid residues A51-Q101.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG