PIPA511592

TLR2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA511592-Each-of-1 In Stock ₹ 47,015.22

PIPA511592 - Each of 1

₹ 47,015.22

In Stock

Quantity

1

Base Price: ₹ 47,015.22

GST (18%): ₹ 8,462.74

Total Price: ₹ 55,477.96

Antigen

TLR2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Tlr2

Gene Alias

CD282; Ly105; TIL4; Tlr2; TLR-2; toll like receptor 2; toll/interleukin-1 receptor-like protein 4; Toll-like receptor; toll-like receptor 2; toll-like receptor 2 variant 1; toll-like receptor 2 variant 2; toll-like-receptor 2, exon 1a_; Toll-like-receptor, exon 1b; Toll-like-receptor, exon 1b_; Toll-like-receptor2, exon 1a

Host Species

Rabbit

Purification Method

Ammonium sulfate precipitation, Size-exclusion - Dialysis

Regulatory Status

RUO

Gene ID (Entrez)

24088

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

2 mg/mL

Formulation

PBS with 0.09% sodium azide

Gene Accession No.

Q9QUN7

Gene Symbols

Tlr2

Immunogen

KLH conjugated synthetic peptide between 720-749 amino acids from the C-terminal region of mouse TLR2

Quantity

400 μL

Primary or Secondary

Primary

Target Species

Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • TLR2 is a member of the Toll-like receptor (TLR) family which play a fundamental role in pathogen recognition and activation of innate immunity
  • TLR proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors such as Protein Kinase C (PKC) alpha/beta and NF-kappa-B
  • TLR2 can form heterodimers with either TLR1 or TLR6, and as a heterodimer, can recognize a variety of bacterial and mycoplasma lipoproteins respectively
  • TLRs are highly conserved from Drosophila to humans and share structural and functional similarities
  • The various TLRs exhibit different patterns of expression
  • TLR2 is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB
  • TLR2 aids in the recognition of pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity
  • Ten human homologs of TLRs (TLR1-10) have been described
  • TLR2 is expressed in human cells such as tonsils, microglia, lymph nodes, and appendices, activated B-cells in germinal centers
  • CD14+ monocytes express the highest level of TLR2 followed by CD15+ granulocytes, CD19+ B-cells, and CD3+ T-cells
  • The expression of TLR2 on different cell types are regulated by different immune response modifiers
  • For example, LPS, GM-CSF, IL-1, and IL-10 up regulates TLR2 whereas IL-4, IFN-gamma, and TNF down regulate TLR2 expression in monocytes.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA511592

--


Antigen:
TLR2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Tlr2

Gene Alias:
CD282; Ly105; TIL4; Tlr2; TLR-2; toll like receptor 2; toll/interleukin-1 receptor-like protein 4; Toll-like receptor; toll-like receptor 2; toll-like receptor 2 variant 1; toll-like receptor 2 variant 2; toll-like-receptor 2, exon 1a_; Toll-like-receptor, exon 1b; Toll-like-receptor, exon 1b_; Toll-like-receptor2, exon 1a

Host Species:
Rabbit

Purification Method:
Ammonium sulfate precipitation, Size-exclusion - Dialysis

Regulatory Status:
RUO

Gene ID (Entrez):
24088

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
2 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
Q9QUN7

Gene Symbols:
Tlr2

Immunogen:
KLH conjugated synthetic peptide between 720-749 amino acids from the C-terminal region of mouse TLR2

Quantity:
400 μL

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5115920

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Antigen:
SLFN11

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SLFN11

Gene Alias:
schlafen family member 11; SLFN11; SLFN8/9

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
91607

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q7Z7L1

Gene Symbols:
SLFN11

Immunogen:
A synthesized peptide derived from human SLFN11(Accession Q7Z7L1), corresponding to amino acid residues I160-S210.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5115921

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Antigen:
SLFN14

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SLFN14

Gene Alias:
BDPLT20; C-terminally truncated SLFN14 endoribonuclease; Gm20; LRRGT00163; Protein SLFN14; schlafen 14; schlafen family member 14; schlafen family member 14, pseudogene; SLFN14; Slfn14-ps

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
342618

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P0C7P3

Gene Symbols:
SLFN14

Immunogen:
A synthesized peptide derived from human SLFN14(Accession P0C7P3), corresponding to amino acid residues G731-G781.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5115924

--


Antigen:
SLIT2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SLIT2

Gene Alias:
downregulated during adipocyte differentiation-1; Drad-1; E030015M03Rik; E130320P19Rik; mKIAA4141; neurogenic extracellular slit protein; SLIL3; Slit; slit guidance ligand 2; slit homolog 2 (Drosophila); slit homolog 2 protein; Slit homolog 2 protein C-product; Slit homolog 2 protein N-product; SLIT2; Slit-2; Slit2 protein

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
360272, 9353

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.:
O94813, Q9WVC1

Gene Symbols:
SLIT2

Immunogen:
A synthesized peptide derived from human SLIT2(Accession O94813), corresponding to amino acid residues N465-T515.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG