PIPA5115931

SMC5 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA5115931-Each-of-1 In Stock ₹ 43,678.38

PIPA5115931 - Each of 1

₹ 43,678.38

In Stock

Quantity

1

Base Price: ₹ 43,678.38

GST (18%): ₹ 7,862.108

Total Price: ₹ 51,540.488

Antigen

SMC5

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Smc5

Gene Alias

hSMC5; KIAA0594; mKIAA0594; MLZ-453; mSMC5; Protein expressed in male leptotene and zygotene spermatocytes 453; SMC protein 5; Smc5; SMC-5; SMC5 structural maintenance of chromosomes 5-like 1; Smc5l1; structural maintenance of chromosomes 5; structural maintenance of chromosomes protein 5

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

226026, 23137, 293967

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.

Q8CG46, Q8IY18

Gene Symbols

Smc5

Immunogen

A synthesized peptide derived from human SMC5(Accession Q8IY18), corresponding to amino acid residues E964-P1014.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total SMC5
  • Core component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination
  • The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks
  • The complex is required for telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines and mediates sumoylation of shelterin complex (telosome) components which is proposed to lead to shelterin complex disassembly in ALT-associated PML bodies (APBs)
  • Required for recruitment of telomeres to PML nuclear bodies
  • Required for sister chromatid cohesion during prometaphase and mitotic progression; the function seems to be independent of SMC6
  • SMC5-SMC6 complex may prevent transcription of episomal DNA, such as circular viral DNA genome.

Compare Similar Items

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Img

Thermo Scientific

PIPA5115931

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Antigen:
SMC5

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Smc5

Gene Alias:
hSMC5; KIAA0594; mKIAA0594; MLZ-453; mSMC5; Protein expressed in male leptotene and zygotene spermatocytes 453; SMC protein 5; Smc5; SMC-5; SMC5 structural maintenance of chromosomes 5-like 1; Smc5l1; structural maintenance of chromosomes 5; structural maintenance of chromosomes protein 5

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
226026, 23137, 293967

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q8CG46, Q8IY18

Gene Symbols:
Smc5

Immunogen:
A synthesized peptide derived from human SMC5(Accession Q8IY18), corresponding to amino acid residues E964-P1014.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5115932

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Antigen:
SMCHD1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SMCHD1

Gene Alias:
4931400A14Rik; AW554188; KIAA0650; mKIAA0650; MommeD1; RGD1307234; SMC hinge domain containing 1; SMC hinge domain-containing protein 1; Smchd1; structural maintenance of chromosomes flexible hinge domain containing 1; structural maintenance of chromosomes flexible hinge domain-containing protein 1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
23347, 316732, 74355

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.:
A6NHR9, Q6P5D8

Gene Symbols:
SMCHD1

Immunogen:
A synthesized peptide derived from human SMCHD1(Accession A6NHR9), corresponding to amino acid residues V1850-L1900.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5115935

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Antigen:
SMURF1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Smurf1

Gene Alias:
4930431E10Rik; E3 ubiquitin ligase SMURF1; E3 ubiquitin ligase SMURF2; E3 ubiquitin-protein ligase SMURF1; E3 ubiquitin-protein ligase SMURF2; HECT-type E3 ubiquitin transferase SMURF1; HECT-type E3 ubiquitin transferase SMURF2; hSMURF1; hSMURF2; KIAA1625; mKIAA1625; RGD1309707; SMAD specific E3 ubiquitin protein ligase 1; SMAD specific E3 ubiquitin protein ligase 2; Smad ubiquitination regulatory factor 1; SMAD ubiquitination regulatory factor 2; Smad-specific E3 ubiquitin ligase 1; SMAD-specific E3 ubiquitin-protein ligase 1; SMAD-specific E3 ubiquitin-protein ligase 2; SMURF1; SMURF2

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
57154, 75788

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q9CUN6, Q9HCE7

Gene Symbols:
Smurf1

Immunogen:
A synthesized peptide derived from human SMURF1(Accession Q9HCE7), corresponding to amino acid residues C174-P224.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5115937

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Antigen:
SMURF2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Smurf2

Gene Alias:
2810411E22Rik; AI558114; AI649275; E3 ubiquitin ligase SMURF2; E3 ubiquitin-protein ligase SMURF2; HECT-type E3 ubiquitin transferase SMURF2; hSMURF2; RGD1310067; SMAD specific E3 ubiquitin protein ligase 2; SMAD ubiquitination regulatory factor 2; SMAD-specific E3 ubiquitin-protein ligase 2; SMURF2

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
303614, 64750, 66313

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.:
A2A5Z6, Q9HAU4

Gene Symbols:
Smurf2

Immunogen:
A synthesized peptide derived from human SMURF2(Accession Q9HAU4), corresponding to amino acid residues G221-H271.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG