PIPA5116693
ADARB1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5116693-Each-of-1 | In Stock | ₹ 44,191.74 |
PIPA5116693 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,191.74
GST (18%): ₹ 7,954.513
Total Price: ₹ 52,146.253
Antigen
ADARB1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
ADARB1
Gene Alias
1700057H01Rik; Adar2; Adarb1; adenosine deaminase, RNA specific B1; adenosine deaminase, RNA-specific, B1; adenosine deaminase, RNA-specific, B1 (homolog of rat RED1); adenosine deaminase, RNA-specific, B1 (RED1 homolog rat); AW124433; AW558573; BB220382; D10Bwg0447e; Double-stranded RNA-specific editase 1; DRABA2; DRADA2; dsRNA adenosine deaminase; dsRNA adenosine deaminase DRADA2; Red1; RED1 homolog; RNA editase; RNA editing deaminase 1; RNA editing deaminase of glutamate receptors; RNA-editing deaminase 1; RNA-editing enzyme 1
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
104, 110532, 25367
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Concentration
0.94 mg/mL
Formulation
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.
P51400, P78563, Q91ZS8
Gene Symbols
ADARB1
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 180-380 of human ADARB1 (NP_0011031)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Positive Samples: U-251MG, HeLa, Jurkat, HepG2, mouse brain, mouse lung, mouse testis, rat brain Immunogen sequence: FETPDKAEPP FYVGSNGDDS FSSSGDLSLS ASPVPASLAQ PPLPVLPPFP PPSGKNPVMI LNELRPGLKY DFLSESGESH AKSFVMSVVV DGQFFEGSGR NKKLAKARAA QSALAAIFNL HLDQTPSRQP IPSEGLQLHL PQVLADAVSR LVLGKFGDLT DNFSSPHARR KVLAGVVMTT GTDVKDAKVI SVSTGTKCIN G Catalyzes the hydrolytic deamination of adenosine to inosine in double-stranded RNA (dsRNA) referred to as A-to-I RNA editing
- This may affect gene expression and function in a number of ways that include mRNA translation by changing codons and hence the amino acid sequence of proteins; pre-mRNA splicing by altering splice site recognition sequences; RNA stability by changing sequences involved in nuclease recognition; genetic stability in the case of RNA virus genomes by changing sequences during viral RNA replication; and RNA structure-dependent activities such as microRNA production or targeting or protein-RNA interactions
- Can edit both viral and cellular RNAs and can edit RNAs at multiple sites (hyper-editing) or at specific sites (site-specific editing)
- Its cellular RNA substrates include: bladder cancer-associated protein (BLCAP), neurotransmitter receptors for glutamate (GRIA2 and GRIK2) and serotonin (HTR2C), GABA receptor (GABRA3) and potassium voltage-gated channel (KCNA1)
- Site-specific RNA editing of transcripts encoding these proteins results in amino acid substitutions which consequently alter their functional activities
- Edits GRIA2 at both the Q/R and R/G sites efficiently but converts the adenosine in hotspot1 much less efficiently
- Can exert a proviral effect towards human immunodeficiency virus type 1 (HIV-1) and enhances its replication via both an editing-dependent and editing-independent mechanism
- The former involves editing of adenosines in the 5'UTR while the latter occurs via suppression of EIF2AK2/PKR activation and function
- Can inhibit cell proliferation and migration and can stimulate exocytosis.
Compare Similar Items
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Antigen: ADARB1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ADARB1
Gene Alias: 1700057H01Rik; Adar2; Adarb1; adenosine deaminase, RNA specific B1; adenosine deaminase, RNA-specific, B1; adenosine deaminase, RNA-specific, B1 (homolog of rat RED1); adenosine deaminase, RNA-specific, B1 (RED1 homolog rat); AW124433; AW558573; BB220382; D10Bwg0447e; Double-stranded RNA-specific editase 1; DRABA2; DRADA2; dsRNA adenosine deaminase; dsRNA adenosine deaminase DRADA2; Red1; RED1 homolog; RNA editase; RNA editing deaminase 1; RNA editing deaminase of glutamate receptors; RNA-editing deaminase 1; RNA-editing enzyme 1
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 104, 110532, 25367
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 0.94 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.: P51400, P78563, Q91ZS8
Gene Symbols: ADARB1
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 180-380 of human ADARB1 (NP_0011031)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
ADARB1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ADARB1
Gene Alias:
1700057H01Rik; Adar2; Adarb1; adenosine deaminase, RNA specific B1; adenosine deaminase, RNA-specific, B1; adenosine deaminase, RNA-specific, B1 (homolog of rat RED1); adenosine deaminase, RNA-specific, B1 (RED1 homolog rat); AW124433; AW558573; BB220382; D10Bwg0447e; Double-stranded RNA-specific editase 1; DRABA2; DRADA2; dsRNA adenosine deaminase; dsRNA adenosine deaminase DRADA2; Red1; RED1 homolog; RNA editase; RNA editing deaminase 1; RNA editing deaminase of glutamate receptors; RNA-editing deaminase 1; RNA-editing enzyme 1
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
104, 110532, 25367
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
0.94 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.:
P51400, P78563, Q91ZS8
Gene Symbols:
ADARB1
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 180-380 of human ADARB1 (NP_0011031)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: ASS1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ASS1
Gene Alias: AA408052; arginino succinate synthetase; argininosuccinate synthase; argininosuccinate synthase 1; argininosuccinate synthetase; argininosuccinate synthetase 1; arginosuccinate synthetase 1; ASS; Ass1; Ass-1; ASSA; citrulline-aspartate ligase; citrulline--aspartate ligase; citrullinemia; CN; CTLN1; fold; mutant arginino succinate synthetase; RP11-618A20.2
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 11898, 25698, 445
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 1.01 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.: P00966, P09034, P16460
Gene Symbols: ASS1
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-412 of human ASS1 (NP_4464641)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
ASS1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ASS1
Gene Alias:
AA408052; arginino succinate synthetase; argininosuccinate synthase; argininosuccinate synthase 1; argininosuccinate synthetase; argininosuccinate synthetase 1; arginosuccinate synthetase 1; ASS; Ass1; Ass-1; ASSA; citrulline-aspartate ligase; citrulline--aspartate ligase; citrullinemia; CN; CTLN1; fold; mutant arginino succinate synthetase; RP11-618A20.2
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
11898, 25698, 445
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
1.01 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.:
P00966, P09034, P16460
Gene Symbols:
ASS1
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-412 of human ASS1 (NP_4464641)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: ATP5I
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Atp5me
Gene Alias: 2610008D24Rik; ATP synthase e chain, mitochondrial; ATP synthase membrane subunit e; ATP synthase subunit e, mitochondrial; ATP synthase subunit e, mitochondrial, N-terminally processed; ATP synthase, H+ transporting, mitochondrial F0 complex, subunit E; ATP synthase, H+ transporting, mitochondrial F1F0 complex, subunit e; ATP synthase, H+ transporting, mitochondrial Fo complex subunit E; ATP synthase, H+ transporting, mitochondrial Fo complex, subunit E; Atp5i; Atp5k; Atp5me; ATPase subunit e; F1F0-ATP synthase, murine e subunit; Lfm1; Lfm-1
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 11958, 140608, 521
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.49 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.: P29419, P56385, Q06185
Gene Symbols: Atp5me
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-69 of human ATP5I (NP_0090311)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
ATP5I
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Atp5me
Gene Alias:
2610008D24Rik; ATP synthase e chain, mitochondrial; ATP synthase membrane subunit e; ATP synthase subunit e, mitochondrial; ATP synthase subunit e, mitochondrial, N-terminally processed; ATP synthase, H+ transporting, mitochondrial F0 complex, subunit E; ATP synthase, H+ transporting, mitochondrial F1F0 complex, subunit e; ATP synthase, H+ transporting, mitochondrial Fo complex subunit E; ATP synthase, H+ transporting, mitochondrial Fo complex, subunit E; Atp5i; Atp5k; Atp5me; ATPase subunit e; F1F0-ATP synthase, murine e subunit; Lfm1; Lfm-1
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
11958, 140608, 521
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.49 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.:
P29419, P56385, Q06185
Gene Symbols:
Atp5me
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-69 of human ATP5I (NP_0090311)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: CD52
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CD52
Gene Alias: AI463198; B7; B7-Ag; cambridge pathology 1 antigen; CAMPATH-1; CAMPATH-1 antigen; Cd52; CD52 antigen; CD52 antigen (CAMPATH-1 antigen); CD52 molecule; CDW52; CDW52 antigen (CAMPATH-1 antigen); CLS1; Epididymal secretory protein E5; epididymis secretory sperm binding protein Li 171mP; he5; HEL-S-171mP; human epididymis-specific protein 5; Lymphocyte differentiation antigen B7; Mb7
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 1043, 23833
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.42 mg/mL
Formulation: PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
Gene Accession No.: P31358, Q64389
Gene Symbols: CD52
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-61 of human CD52 (NP_0017942)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
CD52
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CD52
Gene Alias:
AI463198; B7; B7-Ag; cambridge pathology 1 antigen; CAMPATH-1; CAMPATH-1 antigen; Cd52; CD52 antigen; CD52 antigen (CAMPATH-1 antigen); CD52 molecule; CDW52; CDW52 antigen (CAMPATH-1 antigen); CLS1; Epididymal secretory protein E5; epididymis secretory sperm binding protein Li 171mP; he5; HEL-S-171mP; human epididymis-specific protein 5; Lymphocyte differentiation antigen B7; Mb7
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
1043, 23833
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.42 mg/mL
Formulation:
PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
Gene Accession No.:
P31358, Q64389
Gene Symbols:
CD52
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-61 of human CD52 (NP_0017942)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG