PIPA5117251

Phospho-TSC2 (Ser1387) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA5117251-Each-of-1 In Stock ₹ 45,560.70

PIPA5117251 - Each of 1

₹ 45,560.70

In Stock

Quantity

1

Base Price: ₹ 45,560.70

GST (18%): ₹ 8,200.926

Total Price: ₹ 53,761.626

Antigen

Phospho-TSC2 (Ser1387)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

TSC2

Gene Alias

LAM; Nafld; OTTHUMP00000198394; PPP1R160; protein phosphatase 1, regulatory subunit 160; Rc; renal carcinoma; Tcs2; Tsc2; TSC4; Tuberin; tuberous sclerosis 2; tuberous sclerosis 2 homolog protein; tuberous sclerosis 2 protein; Tuberous sclerosis 2 protein homolog

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

22084, 24855, 7249

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

0.68 mg/mL

Formulation

PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.

P49815, P49816, Q61037

Gene Symbols

TSC2

Immunogen

A synthetic phosphorylated peptide around S1387 of human Tuberin/TSC2 (NP_0005392)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Positive Samples: C2C12 Immunogen sequence: SSSSP TSC2 (Tuberin, Tuberous sclerosis complex, TSC Complex Subunit 2), is implicated as a tumor suppressor and may function in vesicular transport, play a role in the regulation of cell growth arrest and in the regulation of transcription mediated by steroid receptors
  • TSC2 associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin
  • Phosphorylation of tuberin on Ser 939 and Thr 1462 regulates its interaction with hamartin, and is stimulated by various growth factors through the phosphoinositide 3-kinase/Akt pathway
  • TSC2 may have a function in vesicular transport, but may also play a role in the regulation of cell growth arrest and in the regulation of transcription mediated by steroid receptors
  • Interaction between TSC1 and TSC2 may facilitate vesicular docking
  • TSC2 specifically stimulates the intrinsic GTPase activity of the Ras related protein RAP1A and RAB5, suggesting a possible mechanism for its role in regulating cellular growth
  • Mutations in TSC2 lead to constitutive activation of RAP1A in tumors and are involved in diseases such as lymphangioleiomyomatosis and TSC2 angiomyolipoma
  • Alternative splicing results in transcript variants of three different isoforms of TSC2.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA5117251

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Antigen:
Phospho-TSC2 (Ser1387)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TSC2

Gene Alias:
LAM; Nafld; OTTHUMP00000198394; PPP1R160; protein phosphatase 1, regulatory subunit 160; Rc; renal carcinoma; Tcs2; Tsc2; TSC4; Tuberin; tuberous sclerosis 2; tuberous sclerosis 2 homolog protein; tuberous sclerosis 2 protein; Tuberous sclerosis 2 protein homolog

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
22084, 24855, 7249

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.68 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.:
P49815, P49816, Q61037

Gene Symbols:
TSC2

Immunogen:
A synthetic phosphorylated peptide around S1387 of human Tuberin/TSC2 (NP_0005392)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5117253

--


Antigen:
Phospho-Ezrin/Radixin/Moesin (Thr558, Thr567, Thr564)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RDX

Gene Alias:
AA516625; AW146364; C78546; CVIL; CVL; cytovillin; cytovillin 2; DFNB24; epididymis luminal protein 70; epididymis secretory protein Li 105; ESP10; EZR; Ezrin; HEL70; HEL-S-105; membrane-organizing extension spike protein; Moesin; MSN; p81; R75297; radixin; radixin isoform; RDX; VIL2; villin 2; villin 2 (ezrin); villin-2

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
315655, 4478, 54319, 5962, 7430, 81521

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.17 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.:
O35763, P15311, P26038, P31977, P35241

Gene Symbols:
Ezr, MSN, RDX

Immunogen:
A synthetic phosphorylated peptide around T567 of human EZR/RDX/MSNEZR (NP_0033702)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5117254

--


Antigen:
Phospho-BRD4 (Thr204)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
BRD4

Gene Alias:
Brd4; BRD4-NUT FUSION; Brd5; bromodomain containing 4; bromodomain-containing 4; bromodomain-containing 5; bromodomain-containing protein 4; bromodomain-containing protein 4; LOW QUALITY PROTEIN: bromodomain-containing protein 4; CAP; chromosome-associated protein; fsh-like protein; HUNK1; HUNKI; Mcap; mitotic chromosome-associated protein; Protein HUNK1; WI-11513

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
23476, 362844, 57261

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.97 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.:
O60885, Q9ESU6

Gene Symbols:
BRD4

Immunogen:
A synthetic phosphorylated peptide around T204 of human BRD4 (NP_4905971)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5117255

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Antigen:
Phospho-Cdc25A (Ser76)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CDC25A

Gene Alias:
CDC25 isoform A1-CAG; CDC25A; CDC25A2; CDC25A2-CAG isoform; Cdc25m3; cell division cycle 25A; D9Ertd393e; dual specificity phosphatase Cdc25A; EC 3.1.3.48; M-phase inducer phosphatase 1; MPIP1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12530, 171102, 993

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1.51 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.:
P30304, P48964, P48965

Gene Symbols:
CDC25A

Immunogen:
A synthetic phosphorylated peptide around S76 of human CDC25A (NP_0017802)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG