PIPA5117275

Phospho-IkB alpha (Ser32) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA5117275-Each-of-1 In Stock ₹ 45,560.70

PIPA5117275 - Each of 1

₹ 45,560.70

In Stock

Quantity

1

Base Price: ₹ 45,560.70

GST (18%): ₹ 8,200.926

Total Price: ₹ 53,761.626

Antigen

Phospho-IkB alpha (Ser32)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

NFKBIA

Gene Alias

AI462015; ECI-6; ECI-6/IKBA; I kappa B-alpha; I(Kappa)B(alpha); I79_018146; IkappaB alpha; IkappaBalpha; I-kappaBalpha; I-kappa-B-alpha; Ikba; IKBalpha; IKB-alpha; Inhibitor of nuclear factor of kappa light chain gene enhancer in B-cells alpha; Inhibitor of nuclear factor of kappa light chain gene enhancer in B-cells, alpha; MAD3; MAD-3; Major histocompatibility complex enhancer-binding protein MAD3; NF kappa B inhibitor alpha; NF-kappaB inhibitor alpha; NF-kappa-B inhibitor alpha; NFKB inhibitor alpha; NFKBI; Nfkbia; nuclear factor of kappa light chain gene enhancer in B-cells; nuclear factor of kappa light chain gene enhancer in B-cells inhibitor, alpha; nuclear factor of kappa light polyp gene enhancer in B-cell 1; nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha; Rel-associated pp40; REL-associated protein pp40; RL/IF-1

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

18035, 4792

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

0.63 mg/mL

Formulation

PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.

P25963, Q9Z1E3

Gene Symbols

NFKBIA

Immunogen

A synthetic phosphorylated peptide around S32 of human NFKBIA (NP_0653901)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Positive Samples: HeLa, NIH/3T3 Immunogen sequence: HDSGL IkB-alpha is a 40 kDa protein that functions to inhibit NF- kappaB activity
  • The inhibition occurs via protein-protein interaction between I kappaB proteins and NF- kappaB dimers in the cytosol
  • The interaction of I kappa B-alpha with NF- kappaB masks the nuclear localization sequence of NF- kappaB, preventing NF- kappaB translocation to the nucleus
  • A variety of stimuli can activate gene expression by liberating NF- kappaB through the degradation of I kappaB alpha
  • These stimuli include the proinflammatory cytokines TNF- alpha and IL-1 beta, chemokines, PMA, growth factors, LPS, UV irradiation, viral infection, as well as various chemical and physical stresses
  • In humans, the gene is located on the q arm of chromosome 14
  • Activation of NFkB requires that IkB be phosphorylated on specific serine residues, which results in targeted degradation of IkB
  • IkB kinase alpha (IKK alpha), previously designated CHUK, interacts with IkB-alpha and specifically phosphorylates IkB-alpha on the sites that trigger its degradation Serines 32 and 36
  • IKK alpha appears to be critical for NFkB activation in response to proinflammatory cytokines
  • Phosphorylation of IkB by IKK alpha is stimulated by the NFkB inducing kinase (NIK), which itself is a central regulator for NFkB activation in response to TNF and IL-1
  • The functional IKK complex contains three subunits, IKK alpha, IKK beta and IKK gamma, and each appear to make essential contributions to IkB phosphorylation.

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Thermo Scientific

PIPA5117275

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Antigen:
Phospho-IkB alpha (Ser32)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NFKBIA

Gene Alias:
AI462015; ECI-6; ECI-6/IKBA; I kappa B-alpha; I(Kappa)B(alpha); I79_018146; IkappaB alpha; IkappaBalpha; I-kappaBalpha; I-kappa-B-alpha; Ikba; IKBalpha; IKB-alpha; Inhibitor of nuclear factor of kappa light chain gene enhancer in B-cells alpha; Inhibitor of nuclear factor of kappa light chain gene enhancer in B-cells, alpha; MAD3; MAD-3; Major histocompatibility complex enhancer-binding protein MAD3; NF kappa B inhibitor alpha; NF-kappaB inhibitor alpha; NF-kappa-B inhibitor alpha; NFKB inhibitor alpha; NFKBI; Nfkbia; nuclear factor of kappa light chain gene enhancer in B-cells; nuclear factor of kappa light chain gene enhancer in B-cells inhibitor, alpha; nuclear factor of kappa light polyp gene enhancer in B-cell 1; nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha; Rel-associated pp40; REL-associated protein pp40; RL/IF-1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18035, 4792

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.63 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.:
P25963, Q9Z1E3

Gene Symbols:
NFKBIA

Immunogen:
A synthetic phosphorylated peptide around S32 of human NFKBIA (NP_0653901)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5117276

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Antigen:
Phospho-STING (Ser366)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TMEM173

Gene Alias:
2610307O08Rik; endoplasmic reticulum IFN stimulator; endoplasmic reticulum interferon stimulator; ERIS; hMITA; hSTING; hypothetical LOC533661; mediator of IRF3 activation; Mita; mitochondrial mediator of IRF3 activation; mitochondrial transmembrane protein 173; MMITA; Mpys; mSTING; NET23; N-terminal methionine-proline-tyrosine-serine plasma membrane tetraspanner; poSTING; RGD1562552; rSTING; SAVI; Stimulator of interferon genes protein; stimulator of interferon response cGAMP interactor 1; STING; STING1; tm173; Tmem173; Transmembrane protein 173

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
340061

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.4 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3

Gene Accession No.:
Q86WV6

Gene Symbols:
TMEM173

Immunogen:
A synthetic phosphorylated peptide around S366 of human STING/TMEM173 (NP_9380231)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5117277

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Antigen:
BRDT

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
BRDT

Gene Alias:
7420412D09Rik; BRD6; Brdt; bromodomain testis associated; bromodomain testis-specific protein; bromodomain, testis-specific; bromodomain-containing female sterile homeotic-like protein; Cancer/testis antigen 9; CT9; female sterile homeotic-related gene 3; fi25h02; Fsrg3; LOW QUALITY PROTEIN: bromodomain testis-specific protein; RING3-like protein; si:dkeyp-85h7.3; testis-specific bromodomain protein; wu:fi25h02; wu:fi25h02 protein

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
114642, 676

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
Q58F21, Q91Y44

Gene Symbols:
BRDT

Immunogen:
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human BRDT. The exact sequence is proprietary.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5117279

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Antigen:
TMPRSS2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TMPRSS2

Gene Alias:
D16Ertd61e; EC 3.4.219; epitheliasin; FLJ41954; MGC6821; Plasmic transmembrane protein X; PP9284; PRSS10; Serine protease 10; Tmprss2; TMPS2; Transmembrane protease serine 2; Transmembrane protease serine 2 catalytic chain; Transmembrane protease serine 2 non-catalytic chain; transmembrane protease, serine 2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
7113

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1.01 mg/mL

Formulation:
PBS with 20% glycerol and 0.025% ProClin 300; pH 7

Gene Accession No.:
O15393

Gene Symbols:
TMPRSS2

Immunogen:
Recombinant protein encompassing a sequence within the center region of human TMPRSS2. The exact sequence is proprietary.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG