PIPA5118543

Phospho-PLCG2 (Tyr753) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5118543-Each-of-1 In Stock ₹ 41,539.38

PIPA5118543 - Each of 1

₹ 41,539.38

In Stock

Quantity

1

Base Price: ₹ 41,539.38

GST (18%): ₹ 7,477.088

Total Price: ₹ 49,016.468

Antigen

Phospho-PLCG2 (Tyr753)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Plcg2

Gene Alias

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2; APLAID; FCAS3; phosphoinositide phospholipase C; phosphoinositide phospholipase C-gamma-2; phospholipase C gamma 2; phospholipase C, gamma 2; phospholipase C, gamma 2 (phosphatidylinositol-specific); phospholipase C-gamma-2; Phospholipase C-IV; PLC gamma 2; PLC gamma2; PLC- gamma2; PLC gamma-2; PLCG2; Plcg-2; PLC-gamma; PLCgamma2; PLC-gamma-2; PLC-IV

Host Species

Rabbit

Purification Method

sequential chromatography

Regulatory Status

RUO

Gene ID (Entrez)

234779, 29337, 5336

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

P16885, P24135, Q8CIH5

Gene Symbols

Plcg2

Immunogen

A synthesized peptide derived from human PLCG2(Accession P16885), corresponding to amino acid residues around phosphorylated Tyr753.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Related Products

Img

Thermo Scientific

PIPA5119344

--

Img

Thermo Scientific

PIPA5119929

--

Img

Thermo Scientific

PIPA5118887

--

Img

Thermo Scientific

PIPA5118523

--

Img

Thermo Scientific

PIPA5118872

--

Img

Thermo Scientific

PIPA5119828

--

Img

Thermo Scientific

PIPA5118748

--

Img

Thermo Scientific

PIPA5118747

--

Description

  • Antibody detects endogenous levels of PLCG2 only when phosphorylated at Tyrosine 753
  • Phosphoinositide-specific phospholipase C (PLC) plays a crucial role in the initiation of receptor mediated signal transduction through the generation of the two second messengers, inositol 1,4,5-triphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate
  • There are many mammalian PLC isozymes, including PLC beta1, PLC beta2, PLC beta3, PLC beta4, PLC gamma1, PLC gamma2, PLC delta1, PLC delta2 and PLCe
  • PLC delta exists as four different isoforms
  • PLC delta1, a calcium signal amplifier, is activated by an atypical GTP-binding protein
  • In addition, PLC delta1 is an effector for GTP-binding protein transglutaminase II-mediated oxytocin receptor and alpha1B-adrenoreceptor signaling
  • Mouse PLC delta1 is highly expressed in brain, heart, lung and testis
  • PLC delta is abnormally accumulated in autopsied brains with Alzheimer's disease (AD), suggesting that it may play a role in the pathology of AD
  • PLC delta2 is markedly expressed in type II intestinal metaplasia and in the adenocarcinoma
  • When PLC delta2 is expressed in type I intestinal metaplasia, the metaplasia is generally considered benignant, yet evolves toward neoplastic transformation
  • Thus, PLC delta2 expression may be a possible marker of gastric malignant transformation.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA5118543

--


Antigen:
Phospho-PLCG2 (Tyr753)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Plcg2

Gene Alias:
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2; APLAID; FCAS3; phosphoinositide phospholipase C; phosphoinositide phospholipase C-gamma-2; phospholipase C gamma 2; phospholipase C, gamma 2; phospholipase C, gamma 2 (phosphatidylinositol-specific); phospholipase C-gamma-2; Phospholipase C-IV; PLC gamma 2; PLC gamma2; PLC- gamma2; PLC gamma-2; PLCG2; Plcg-2; PLC-gamma; PLCgamma2; PLC-gamma-2; PLC-IV

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
234779, 29337, 5336

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P16885, P24135, Q8CIH5

Gene Symbols:
Plcg2

Immunogen:
A synthesized peptide derived from human PLCG2(Accession P16885), corresponding to amino acid residues around phosphorylated Tyr753.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5118546

--


Antigen:
Phospho-Synaptotagmin 1/2 (Thr202)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SYT1

Gene Alias:
AW124717; CMS7; FLJ42519; G630098F17Rik; Inositol polyphosphate-binding protein; IP4-binding protein; mKIAA4194; MYSPC; p65; R74640; RATSYNII; SVP65; synaptotagmin 1; synaptotagmin 2; synaptotagmin I; Synaptotagmin II; synaptotagmin-1; Synaptotagmin-2; SYNII; SYT; SYT1; SYT2; SytI; sytII

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
127833, 20979, 20980, 24805, 25716, 6857

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P21579, P21707, P29101, P46096, P46097, Q8N9I0

Gene Symbols:
SYT1, SYT2

Immunogen:
A synthesized peptide derived from human SYT1(Accession P21579), corresponding to amino acid residues around phosphorylated Thr202.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5118547

--


Antigen:
Phospho-Cyclin D1 (Ser90)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CCND1

Gene Alias:
AI327039; B-cell CLL/lymphoma 1; B-cell lymphoma 1 protein; BCL1; BCL-1; BCL-1 oncogene; CCND1; CCND1 protein; cD1; cDNA; CycD1; cyclin D1; Cyl-1; D11S287E; FLJ93625; G1/S-specific cyclin-D1; mRNA; PRAD1; PRAD-1; PRAD1 oncogene; U21B31

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12443, 58919, 595

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P24385, P25322, P39948

Gene Symbols:
CCND1

Immunogen:
A synthesized peptide derived from human CCND1(Accession P24385), corresponding to amino acid residues around phosphorylated Ser90.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5118556

--


Antigen:
Phospho-JNK1/JNK2/JNK3 (Thr183, Tyr185)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MAPK8

Gene Alias:
AI849689; AI851083; C230008H04Rik; c-Jun kinase 2; c-Jun N-terminal kinase 1; c-Jun N-terminal kinase 2; c-Jun N-terminal kinase 3; FLJ12099; FLJ33785; hypothetical protein LOC569698; janus kinase 1; janus kinase 2; JNK; JNK 46; JNK 55; JNK/SAPK alpha; JNK1; JNK1 beta1 protein kinase; JNK1A2; Jnk2; JNK21B1/2; JNK2A; JNK2ALPHA; JNK2B; JNK2BETA; Jnk3; JNK3 alpha protein kinase; JNK3 beta1 protein kinase; JNK3 beta2 protein kinase; JNK3A; JNK3B1; JNK3B2; JNK-46; JNK-55; Jun kinase; JUN N-terminal kinase; MAP kinase 10; MAP kinase 8; MAP kinase 9; MAP kinase p49 3F12; MAPK 10; MAPK 8; MAPK 9; Mapk10; Mapk8; Mapk9; MGC137545 protein; MGC50974; Mi; mitogen activated protein kinase 10; mitogen activated protein kinase 8; mitogen activated protein kinase 9; mitogen-activated protein kinase 10; Mitogen-activated protein kinase 8; mitogen-activated protein kinase 8 isoform JNK1 alpha1; mitogen-activated protein kinase 8 isoform JNK1 beta2; mitogen-activated protein kinase 9; MK10; p493F12; p54 gamma; p54a; p54-alpha; p54aSAPK; p54-beta; p54bSAPK; Phospho-JNK; PRKM10; Prkm8; PRKM9; protein kinase mitogen-activated 8; protein kinase, mitogen-activated 9; SAPb; SAPK; SAPK gamma; SAPK(beta); SAPK/Erk/kinase 2; SAPK1; SAPK1a; SAPK1B; SAPK1c; SAPK-alpha; SAPK-beta; SAPKC; Serk2; si:ch211-247j9.2; stress activated protein kinase alpha II; Stress activated protein kinase beta; stress-activated protein kinase 1; stress-activated protein kinase 1a; Stress-activated protein kinase 1b; stress-activated protein kinase 1c; Stress-activated protein kinase JNK1; stress-activated protein kinase JNK2; Stress-activated protein kinase JNK3; zgc:123234

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
116554, 25272, 26414, 26419, 26420, 50658, 5599, 5601, 5602

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P45983, P45984, P49185, P49186, P49187, P53779, Q61831, Q91Y86, Q9WTU6

Gene Symbols:
MAPK10, MAPK8, MAPK9

Immunogen:
A synthesized peptide derived from human MAPK8(Accession P45983), corresponding to amino acid residues around phosphorylated Thr183.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG